Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mark D Krailo"'
Autor:
Michael J Monument, Kirsten M Johnson, Elizabeth McIlvaine, Lisa Abegglen, W Scott Watkins, Lynn B Jorde, Richard B Womer, Natalie Beeler, Laura Monovich, Elizabeth R Lawlor, Julia A Bridge, Joshua D Schiffman, Mark D Krailo, R Lor Randall, Stephen L Lessnick
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104378 (2014)
The genetics involved in Ewing sarcoma susceptibility and prognosis are poorly understood. EWS/FLI and related EWS/ETS chimeras upregulate numerous gene targets via promoter-based GGAA-microsatellite response elements. These microsatellites are highl
Externí odkaz:
https://doaj.org/article/4751ee6c02754a9b8aa6e02b50c6dade
Autor:
Lin Xu, Joshua L. Pierce, Angelica Sanchez, Kenneth S. Chen, Abhay A. Shukla, Nicholas J. Fustino, Sarai H. Stuart, Aditya Bagrodia, Xue Xiao, Lei Guo, Mark D. Krailo, Furqan Shaikh, Deborah F. Billmire, Farzana Pashankar, Jessica Bestrashniy, J. Wolter Oosterhuis, Ad J. M. Gillis, Yang Xie, Lisa Teot, Jaume Mora, Jenny N. Poynter, Dinesh Rakheja, Leendert H. J. Looijenga, Bruce W. Draper, A. Lindsay Frazier, James F. Amatruda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Germ cell tumors (GCTs) are neoplasms of the testis, ovary and extragonadal sites that occur in infants, children, adolescents and adults. Post-pubertal (type II) malignant GCTs may present as seminoma, non-seminoma or mixed histologies. In
Externí odkaz:
https://doaj.org/article/7de0ec00eddb4344af90c7a9512816da
Autor:
Lisa M. Kopp, Richard B. Womer, Cindy L. Schwartz, David H. Ebb, Vivian I. Franco, David Hall, Donald A. Barkauskas, Mark D. Krailo, Holcombe E. Grier, Paul A. Meyers, Leonard H. Wexler, Neyssa M. Marina, Katherine A. Janeway, Richard Gorlick, Mark L. Bernstein, Steven E. Lipshultz, for the Children’s Oncology Group
Publikováno v:
Cardio-Oncology, Vol 5, Iss 1, Pp 1-12 (2019)
Abstract Background Dexrazoxane protects from lower-cumulative-dose doxorubicin cardiotoxicity, but the effect of dexrazoxane in children with sarcoma treated with higher-cumulative-dose doxorubicin is unknown. Methods We evaluated children with oste
Externí odkaz:
https://doaj.org/article/c1df26e926ca40859f1f7499883d65cd
Autor:
Samuel Abbou, Kelly Klega, Junko Tsuji, Mohammad Tanhaemami, David Hall, Donald A. Barkauskas, Mark D. Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R. Thorner, Samuel Pollock, Alma Imamovic-Tuco, Jack F. Shern, Steven G. DuBois, Rajkumar Venkatramani, Douglas S. Hawkins, Brian D. Crompton
Publikováno v:
Journal of Clinical Oncology. 41:2382-2393
PURPOSE Novel biomarkers are needed to differentiate outcomes in intermediate-risk rhabdomyosarcoma (IR RMS). We sought to evaluate strategies for identifying circulating tumor DNA (ctDNA) in IR RMS and to determine whether ctDNA detection before the
Autor:
Steven G. DuBois, Mark D. Krailo, Julia Glade-Bender, Allen Buxton, Nadia Laack, R. Lor Randall, Helen X. Chen, Nita L. Seibel, Matthew Boron, Stephanie Terezakis, Christine Hill-Kayser, Andrea Hayes, Joel M. Reid, Lisa Teot, Dinesh Rakheja, Richard Womer, Carola Arndt, Stephen L. Lessnick, Brian D. Crompton, E. Anders Kolb, Heike Daldrup-Link, Eric Eutsler, Damon R. Reed, Katherine A. Janeway, Richard G. Gorlick
Publikováno v:
Journal of Clinical Oncology. 41:2098-2107
PURPOSE Monoclonal antibodies directed against insulin-like growth factor-1 receptor (IGF-1R) have shown activity in patients with relapsed Ewing sarcoma. The primary objective of Children's Oncology Group trial AEWS1221 was to determine if the addit
Autor:
Sanjeev A Vasudevan, Rebecka L Meyers, Milton J Finegold, Dolores López-Terrada, Sarangarajan Ranganathan, Stephen P Dunn, Max R Langham, Eugene D McGahren, Greg M Tiao, Christopher B Weldon, Marcio H Malogolowkin, Mark D Krailo, Jin Piao, Jessica Randazzo, Alexander J Towbin, M. BethMcCarville, Allison F O'Neill, Wayne L Furman, Carlos Rodriguez-Galindo, Howard M Katzenstein
Publikováno v:
Journal of Pediatric Surgery. 57:251-256
Hepatoblastoma (HB) requires surgical resection for cure, but only 20-30% of patients have resectable disease at diagnosis. Patients who undergo partial hepatectomy at diagnosis have historically received 4-6 cycles of adjuvant chemotherapy; however,
Autor:
Patrick A. Thompson, Marcio H. Malogolowkin, Wayne L. Furman, Jin Piao, Mark D. Krailo, Nadia Chung, Lindsay Brock, Alexander J. Towbin, Elizabeth B. McCarville, Milton J. Finegold, Sarangarajan Ranganathan, Stephen P. Dunn, Max R. Langham, Eugene D. McGahren, Gregory M. Tiao, Christopher B. Weldon, Allison F. O'Neill, Carlos Rodriguez‐Galindo, Rebecka L. Meyers, Howard M. Katzenstein
Publikováno v:
Pediatric Blood & Cancer. 70
Autor:
Steven G. DuBois, Crystal L. Mackall, Stephen L. Lessnick, Richard G. Gorlick, Richard B. Womer, Katherine K. Matthay, Donald A. Barkauskas, Mark D. Krailo, Elizabeth McIlvaine, Phillip Barnette, Katherine A. Janeway, Holcombe E. Grier, Douglas S. Hawkins, Elizabeth Sinclair, C. Lorrie Epling, Jeremy V. Edwards, Kieuhoa T. Vo
Supplemental Table 1. Association of clinical features with BM micrometastatic cell burden (CD99+CD45- percent) in flow cytometry cohort. Supplemental Table 2. Total CD99+CD45- percent burden in Ewing sarcoma patients with clinically evident BM metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231c81b01ab283631b8f4ce8da780d85
https://doi.org/10.1158/1078-0432.22457171
https://doi.org/10.1158/1078-0432.22457171
Autor:
Steven G. DuBois, Crystal L. Mackall, Stephen L. Lessnick, Richard G. Gorlick, Richard B. Womer, Katherine K. Matthay, Donald A. Barkauskas, Mark D. Krailo, Elizabeth McIlvaine, Phillip Barnette, Katherine A. Janeway, Holcombe E. Grier, Douglas S. Hawkins, Elizabeth Sinclair, C. Lorrie Epling, Jeremy V. Edwards, Kieuhoa T. Vo
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma.Experimental Design: Newly diagnosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64770d357efe2df1e42c36dc5754ae65
https://doi.org/10.1158/1078-0432.c.6523523
https://doi.org/10.1158/1078-0432.c.6523523
Autor:
Axel Budde, Katja Baust, Leonie Weinhold, Mark Bernstein, Stefan Bielack, Catharina Dhooge, Lars Hjorth, Katherine A. Janeway, Meriel Jenney, Mark D. Krailo, Neyssa Marina, Rajaram Nagarajan, Sigbjørn Smeland, Matthew R. Sydes, Patricia De Vos, Jeremy Whelan, Andreas Wiener, Gabriele Calaminus, Matthias Schmid
Publikováno v:
European Journal of Cancer. 177:208-209