Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Mark D Handschumacher"'
Autor:
Yue Zhang, Vicky Y Wang, Ashley E Morgan, Jiwon Kim, Mark D Handschumacher, Chaya S Moskowitz, Robert A Levine, Liang Ge, Julius M Guccione, Jonathan W Weinsaft, Mark B Ratcliffe
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223472 (2019)
PurposeMitraClip is the sole percutaneous device approved for functional mitral regurgitation (MR; FMR) but MR recurs in over one third of patients. As device-induced mechanical effects are a potential cause for MR recurrence, we tested the hypothesi
Externí odkaz:
https://doaj.org/article/f4a277b8422b4be888376f23cde24606
Autor:
Ons Marsit, Marie-Annick Clavel, Amélie Paquin, Valérie Deschênes, Sandra Hadjadj, Isabelle Sénéchal-Dumais, Jacques Couet, Marie Arsenault, Mark D. Handschumacher, Robert A. Levine, Elena Aikawa, Philippe Pibarot, Jonathan Beaudoin
Publikováno v:
Journal of the American College of Cardiology. 80(5)
Ischemic mitral regurgitation (MR) is primarily caused by left ventricle deformation, but leaflet thickening with fibrotic changes are also observed in the valve. Increased levels of 5-hydroxytryptamine (5-HT; ie, serotonin) are described after myoca
Autor:
Yong-Hyun Park, Cashel O’Brien, Mark D. Handschumacher, José Luiz Padilha da Silva, Maria do Carmo Pereira Nunes, Xin Zeng, Gyeong-Moon Kim, Judy Hung, Victoria Piro, Hakan Ay, Johanna Helenius, Timothy C. Tan, Karen L. Furie, Octavio M. Pontes-Neto
Publikováno v:
Heart. 106:1176-1182
ObjectiveCardioembolic (CE) stroke carries significant morbidity and mortality. Left atrial (LA) size has been associated with CE risk. We hypothesised that differential LA remodelling impacts on pathophysiological mechanism of major CE strokes.Metho
Autor:
Hong-Kyung Park, Joyce Bischoff, Kyu-Ri Kim, Robert A. Levine, Ran Heo, Jae-Kwan Song, Yewon Shin, Duk-Hyun Kang, Yun-Sil Choi, Mark D. Handschumacher, Dae-Hee Kim, Sahmin Lee, Jong-Min Song, Elena Aikawa
Publikováno v:
JACC: Cardiovascular Imaging. 12:665-677
Objectives This study hypothesized that compensatory mitral leaflet area (MLA) adaptation occurs in patients with persistent atrial fibrillation (AF) without left ventricular (LV) dysfunction but has limitations that augment mitral regurgitation (MR)
Autor:
Bruna Morhy Borges Leal Assuncao, Kai-Hung Cheng, Evin Yucel, Mark D. Handschumacher, Timothy C. Tan, Philipp E. Bartko, Andrew M. Brunner, Orlando Campos, Amir T. Fathi, Marielle Scherrer-Crosbie
Publikováno v:
Journal of the American Society of Echocardiography. 30:1111-1118
Patients with acute leukemia (AL) have a higher rate of congestive heart failure than patients with other cancers. AL may predispose to cardiac dysfunction before chemotherapy because of high cytokine release or direct leukemic myocardial infiltratio
Autor:
Elkan F. Halpern, Mark D. Handschumacher, Igal A. Sebag, Kai-Hung Cheng, Bruna Morhy Borges Leal Assuncao, Marielle Scherrer-Crosbie
Publikováno v:
Journal of the American Society of Echocardiography. 30:454-460
During the development of heart failure (HF), the changes of contraction timing pattern and temporal heterogeneity of segmental contraction happen early and may precede both symptomatic HF and the decrease in left ventricular ejection fraction (LVEF)
Autor:
Marie-Claude Drolet, J. Luis Guerrero, Patrick Mathieu, Marie-Annick Clavel, Jonathan Beaudoin, Claudia Côté-Laroche, Ons Marsit, Marie Arsenault, Marie-Chloé Boulanger, Dae-Hee Kim, Robert A. Levine, Philipp E. Bartko, Elena Aikawa, Joyce Bischoff, Mark D. Handschumacher, Sandra Hadjadj, Marc-André Bouchard, Jacques Couet, Marine Clisson, Philippe Pibarot
Publikováno v:
Journal of the American College of Cardiology. 75(4)
Background Mitral leaflet enlargement has been identified as an adaptive mechanism to prevent mitral regurgitation in dilated left ventricles (LVs) caused by chronic aortic regurgitation (AR). This enlargement is deficient in patients with functional
Autor:
Ashley E Morgan, Liang Ge, Robert A. Levine, Yue Zhang, Chaya S. Moskowitz, Mark D. Handschumacher, Vicky Y. Wang, Julius M. Guccione, Mark B. Ratcliffe, Jonathan W. Weinsaft, Jiwon Kim
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223472 (2019)
PLoS ONE
PLoS ONE
PurposeMitraClip is the sole percutaneous device approved for functional mitral regurgitation (MR; FMR) but MR recurs in over one third of patients. As device-induced mechanical effects are a potential cause for MR recurrence, we tested the hypothesi
Autor:
Suzanne Sullivan, Mark D. Handschumacher, J. Luis Guerrero, Robert A. Levine, Gavin J. C. Braithwaite, Gus J. Vlahakes, Xin Zeng, James R. Stone, Judy Hung, Jorge Solis, Lin Zou, Orhun K. Muratoglu
Publikováno v:
JACC: Cardiovascular Interventions. 8:355-363
Objectives The aim of this study was to examine the chronic effects of polyvinyl-alcohol (PVA) injection on mitral regurgitation (MR) reduction, mitral valve geometry, and left ventricular (LV) remodeling in a chronic ischemic MR sheep model. Backgro
Autor:
Suzanne Sullivan, Mark D. Handschumacher, Philipp E. Bartko, J. Luis Guerrero, Jill Wylie-Sears, Margo M. Seybolt, Whitney S. Irvin, Dae-Hee Kim, Catherine Szymanski, Robert A. Levine, Elena Aikawa, Albert Hagège, Joyce Bischoff, Michael L. Garcia, Emmanuel Messas, Jonathan Beaudoin, Jacob P. Dal-Bianco, Alain Carpentier, James S. Titus
After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment mitral regurgitation (MR), doubling heart failure and mortality. MV fibrosis post-MI is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7786271082081710c01a8c19773d9d12
https://europepmc.org/articles/PMC5679094/
https://europepmc.org/articles/PMC5679094/