Zobrazeno 1 - 10 of 268 pro vyhledávání: '"Mark D, Pegram"'
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Akademický článek
Clinical validation of an immunohistochemistry‐based CanAssist‐Breast test for distant recurrence prediction in hormone receptor‐positive breast cancer patients
Autor: Manjiri M. Bakre, Charusheila Ramkumar, Arun Kumar Attuluri, Chetana Basavaraj, Chandra Prakash, Ljubomir Buturovic, Lekshmi Madhav, Nirupama Naidu, Prathima R, S. P. Somashekhar, Sudeep Gupta, Dinesh Chandra Doval, Mark D. Pegram
Publikováno v: Cancer Medicine, Vol 8, Iss 4, Pp 1755-1764 (2019)
Abstract CanAssist‐Breast (CAB) is an immunohistochemistry (IHC)‐based prognostic test for early‐stage Hormone Receptor (HR+)‐positive breast cancer patients. CAB uses a Support Vector Machine (SVM) trained algorithm which utilizes expression
Externí odkaz: https://doaj.org/article/9e0599c8445a41efaf55c1598f1c78cc
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4
Akademický článek
Single-cell immunoblotting resolves estrogen receptor-α isoforms in breast cancer.
Autor: John J Kim, Wenchuan Liang, Chi-Chih Kang, Mark D Pegram, Amy E Herr
Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0254783 (2021)
An array of isoforms of the nuclear estrogen receptor alpha (ER-α) protein contribute to heterogeneous response in breast cancer (BCa); yet, a single-cell analysis tool that distinguishes the full-length ER-α66 protein from the activation function-
Externí odkaz: https://doaj.org/article/9775623135fe4148b38d349814c57b13
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6
Supplementary Data from Extracellular Vesicle–Mediated In Vitro Transcribed mRNA Delivery for Treatment of HER2+ Breast Cancer Xenografts in Mice by Prodrug CB1954 without General Toxicity
Autor: A.C. Matin, Stefanie S. Jeffrey, Mark D. Pegram, Carol Green, Kyuri Kim, Alain Delcayre, Jing-Hung Wang, Alexis V. Forterre
Supplementary Figure S1 shows composition of the EVHB protein and making of EXO-DEPTS. Supplementary Figure S2 shows the size and proteins that characterize extracellular vesicles. Supplementary Figure S3 shows that the mRNA is inside the extracellul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d378159a3fd0f660941174d3e293c6
https://doi.org/10.1158/1535-7163.22519105
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Data from Extracellular Vesicle–Mediated In Vitro Transcribed mRNA Delivery for Treatment of HER2+ Breast Cancer Xenografts in Mice by Prodrug CB1954 without General Toxicity
Autor: A.C. Matin, Stefanie S. Jeffrey, Mark D. Pegram, Carol Green, Kyuri Kim, Alain Delcayre, Jing-Hung Wang, Alexis V. Forterre
Prodrugs are harmless until activated by a bacterial or viral gene product; they constitute the basis of gene-delivered prodrug therapies called GDEPT, which can kill tumors without major side effects. Previously, we utilized the prodrug CNOB (C16H7C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c2bb609fd3888c4aba2aa53919a0c9
https://doi.org/10.1158/1535-7163.c.6542296.v1
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