Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Mark D, Parker"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
SLC4A11 is the most abundant membrane transport protein in corneal endothelial cells. Its functional presence is necessary to support the endothelial fluid pump that draws fluid from the corneal stroma, preventing corneal edema. Several molecular act
Externí odkaz:
https://doaj.org/article/a0a089e4f3e44727a7006d971e56a00a
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The sodium-bicarbonate cotransporter (NBCe1) has three primary variants: NBCe1-A, -B and -C. NBCe1-A is expressed in renal proximal tubules in the cortical labyrinth, where it is essential for reclaiming filtered bicarbonate, such that NBCe1-A knocko
Externí odkaz:
https://doaj.org/article/88ab2e4eea484109834928cf6c1d73b9
Autor:
Seong-Ki Lee, Rossana Occhipinti, Fraser J. Moss, Mark D. Parker, Irina I. Grichtchenko, Walter F. Boron
Publikováno v:
Journal of the American Society of Nephrology. 34:40-54
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C990-C1002
Mutations in the H+(OH−) conductor SLC4A11 result in corneal endothelial dystrophy. In previous studies using mouse Slc4a11, we showed that the pK value that governs the intracellular pH dependence of SLC4A11 (pKi) is influenced by extracellular pH
Autor:
Thamer A. Alsufayan, Evan J. Myers, Bianca N. Quade, Clayton T. Brady, Aniko Marshall, Nayem Haque, Michael E. Duffey, Mark D. Parker
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12817 (2021)
In most cell types and heterologous expression systems, the electrogenic sodium-bicarbonate cotransporter NBCe1 operates with a 1Na+–2HCO3− stoichiometry that, given typical transmembrane electrochemical gradients, promotes Na+ and HCO3− influx
Externí odkaz:
https://doaj.org/article/0af818bb1e624e8c8935d8d4f609a240
Autor:
Abigail C. Cornwell, Arwen A. Tisdale, Swati Venkat, Kathryn E. Maraszek, Abdulrahman A. Alahmari, Anthony George, Kristopher Attwood, Madison George, Donald Rempinski, Janusz Franco-Barraza, Mark D. Parker, Eduardo Cortes Gomez, Christos Fountzilas, Edna Cukierman, Nina G. Steele, Michael E. Feigin
PurposeThis research investigates the association between benzodiazepines (BZDs) and cancer patient survival outcomes. Due to the high prevalence of BZD use in pancreatic cancer patients, we evaluated the effect of commonly prescribed BZDs on the pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::220f100f0586d5ba193768ba4cdb9bba
https://doi.org/10.1101/2023.03.01.23286581
https://doi.org/10.1101/2023.03.01.23286581
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 201 (2020)
Monocarboxylate transporter 6 (MCT6; SLC16A5) is a recently studied drug transporter that currently has no annotated endogenous function. Currently, only a handful of compounds have been characterized as substrates for MCT6 (e.g., bumetanide, nategli
Externí odkaz:
https://doaj.org/article/889bee405e80438ba194ce17fd3aef27
Autor:
Ilse Foissner, Bianca N. Quade, Mark D. Parker, Mary A. Bisson, Mary J. Beilby, Shaunna Phipps, Marion C. Hoepflinger
Publikováno v:
Protoplasma. 259:615-626
Characeae are closely related to the ancient algal ancestors of all land plants. The long characean cells display a pH banding pattern to facilitate inorganic carbon import in the acid zones for photosynthetic efficiency. The excess OH−, generated
Autor:
Zachary J. Schlader, David Hostler, Mark D. Parker, Riana R. Pryor, James W. Lohr, Blair D. Johnson, Christopher L. Chapman
Publikováno v:
Nutrients, Vol 11, Iss 9, p 2087 (2019)
An epidemic of chronic kidney disease (CKD) is occurring in laborers who undertake physical work in hot conditions. Rodent data indicate that heat exposure causes kidney injury, and when this injury is regularly repeated it can elicit CKD. Studies in
Externí odkaz:
https://doaj.org/article/454182dca45549958c9de80b62bddda6
Publikováno v:
Biophysical Journal. 122:519a