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Autor:
Esther C W, Breij, W-Ludo, van der Pol, Lisa, van Winsen, Mark D, Jansen, Christine D, Dijkstra, Jan G J, van de Winkel, Bernard M J, Uitdehaag
Publikováno v:
Journal of neuroimmunology. 140(1-2)
Anti-myelin IgGs occur in the cerebrospinal fluid (CSF) and serum of multiple sclerosis (MS) patients, and can induce inflammatory effector functions in leukocytes by crosslinking IgG receptors (FcgammaR). The efficiency of FcgammaR-mediated inflamma