Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Mark D, Hylarides"'
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Pretargeted radioimmunotherapy (PRIT) has been investigated as a multi-step approach to decrease relapse and toxicity for high-risk acute myeloid leukemia (AML). Relevant factors including endogenous biotin and immunogenicity, however, have limited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cb196c04e590eb312858a4d9061fed
https://doi.org/10.1158/1535-7163.c.6542662
https://doi.org/10.1158/1535-7163.c.6542662
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Supplementary Materials, Methods and relevant AA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c057d8965675ca7f790ca8236eb48a
https://doi.org/10.1158/1535-7163.22520518.v1
https://doi.org/10.1158/1535-7163.22520518.v1
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Table S1 presents mouse survival data for in vivo experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1f8931fda4e9dec0f52f77d94c1a28
https://doi.org/10.1158/0008-5472.22414092.v1
https://doi.org/10.1158/0008-5472.22414092.v1
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Figures including: Supplemental Figure 1- Dose finding pharmacokinetics. Supplemental Figure 2- Dose finding tissue biodistribution. Supplemental Figure 3- body weight over time in a therapy study. Supplemental Figure 4- blood counts over time in a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fa9ad6c582f79e53958516ac3c2d49
https://doi.org/10.1158/0008-5472.22413027
https://doi.org/10.1158/0008-5472.22413027
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Streptavidin (SA)-biotin pretargeted radioimmunotherapy (PRIT) that targets CD20 in non-Hodgkin lymphoma (NHL) exhibits remarkable efficacy in model systems, but SA immunogenicity and interference by endogenous biotin may complicate clinical translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dc53f403d5241580b8113781f0a0c07
https://doi.org/10.1158/0008-5472.c.6508593.v1
https://doi.org/10.1158/0008-5472.c.6508593.v1
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Constitutive B-cell receptor signaling leads to overexpression of the antiapoptotic BCL-2 protein and is implicated in the pathogenesis of many types of B-cell non-Hodgkin lymphoma (B-NHL). The BCL-2 small-molecule inhibitor venetoclax shows promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba29fc239fe41412deedcbacf1fa7d0
https://doi.org/10.1158/0008-5472.c.6508887.v1
https://doi.org/10.1158/0008-5472.c.6508887.v1
Autor:
John M. Pagel, D. Scott Wilbur, Oliver W. Press, Mark D. Hylarides, Damian J. Green, Darrell R. Fisher, Mazyar Shadman, Alexandra Hernandez, Johnnie J. Orozco, Aimee Kenoyer, Ethan R. Balkin
Supplemental Figure 2. Cerenkov Light Images of excised organs. Groups of 5 mice were given 300 µCi on 100 µg of 90Y-DOTA-30F11 (A), 177Lu-DOTA-30F11 (B), 90Y-DOTA-Rat IgG (C), or 177Lu-DOTA-Rat IgG (D). Groups of mice were harvested and images col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78dc7264303f0bbf30dd5e7bef9e1f77
https://doi.org/10.1158/0008-5472.22403349.v1
https://doi.org/10.1158/0008-5472.22403349.v1
Autor:
John M. Pagel, D. Scott Wilbur, Oliver W. Press, Mark D. Hylarides, Damian J. Green, Darrell R. Fisher, Mazyar Shadman, Alexandra Hernandez, Johnnie J. Orozco, Aimee Kenoyer, Ethan R. Balkin
Supplemental Figure 1. In vitro phantom containing 100 μCi 177Lu. Phantom images were obtained by placing a minimal volume of activity source within a 1.5 mL polypropylene tube, which was then suspended in water inside a larger polypropylene tube. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a046feaf189d9529b942eebb45f4a8
https://doi.org/10.1158/0008-5472.22403352
https://doi.org/10.1158/0008-5472.22403352
Autor:
Oliver W. Press, William I. Bensinger, Brent L. Wood, Theodore A. Gooley, Johnnie J. Orozco, Ajay K. Gopal, Shani L. Frayo, Aimee L. Kenoyer, Darrell R. Fisher, Yukang Lin, D.S. Wilbur, Donald K. Hamlin, John M. Pagel, Mark D. Hylarides, Jon C. Jones, Nural N. Orgun, Damian J. Green
The vast majority of patients with plasma cell neoplasms die of progressive disease despite high response rates to novel agents. Malignant plasma cells are very radiosensitive, but the potential role of radioimmunotherapy (RIT) in the management of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5e44fccb2ce33ee2561644e5b6427e
https://doi.org/10.1158/0008-5472.c.6505673
https://doi.org/10.1158/0008-5472.c.6505673
Autor:
Oliver W. Press, William I. Bensinger, Brent L. Wood, Theodore A. Gooley, Johnnie J. Orozco, Ajay K. Gopal, Shani L. Frayo, Aimee L. Kenoyer, Darrell R. Fisher, Yukang Lin, D.S. Wilbur, Donald K. Hamlin, John M. Pagel, Mark D. Hylarides, Jon C. Jones, Nural N. Orgun, Damian J. Green
PDF - 156K, Supplementary Figure 1, demonstrating CD38 receptor surface stability. Supplementary Figure 2, demonstrating animal body weight following anti-CD38 pretargeted radioimmunotherapy. Supplemental methods describing fusion protein constructio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4838aea0b499623f63cad0d93d2dbf00
https://doi.org/10.1158/0008-5472.22400780
https://doi.org/10.1158/0008-5472.22400780