Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mark D, Bonnen"'
Autor:
Afshin Ebrahimpour, Manisha Ahir, Min Wang, Anil G. Jegga, Mark D. Bonnen, N. Tony Eissa, Sydney B. Montesi, Ganesh Raghu, Yohannes T. Ghebre
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease of unknown etiology. Currently, pirfenidone and nintedanib are the only FDA-approved drugs for the treatment of IPF and are now the standard of care. This is a signi
Externí odkaz:
https://doaj.org/article/3ce6a0a83e064759a2ff579276fe6229
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Historically, the effort by academia and industry to develop new chemical entities into lifesaving drugs has limited success in meeting the demands of today’s healthcare. Repurposing drugs that are originally approved by the United States Food and
Externí odkaz:
https://doaj.org/article/5f7302f5a32948c5ab807c19e6730d2d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
This review article outlines six molecular pathways that confer resistance of cancer cells to ionizing radiation, and describes how proton pump inhibitors (PPIs) may be used to overcome radioresistance induced by alteration of one or more of these si
Externí odkaz:
https://doaj.org/article/66dff6de1c19474ba5b14a3b6a2381bb
Autor:
Afshin Ebrahimpour, Min Wang, Li Li, Anil G. Jegga, Mark D. Bonnen, N. Tony Eissa, Ganesh Raghu, Soma Jyothula, Farrah Kheradmand, Nicola A. Hanania, Ivan O. Rosas, Yohannes T. Ghebre
Publikováno v:
Journal of Inflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Introduction Idiopathic pulmonary fibrosis (IPF) is an orphan disease characterized by progressive loss of lung function resulting in shortness of breath and often death within 3–4 years of diagnosis. Repetitive lung injury in susceptible
Externí odkaz:
https://doaj.org/article/e4e7d799ccab4aaabac4af93292863d5
Publikováno v:
Frontiers in Psychology, Vol 9 (2018)
Background: Head and neck cancer (HNC) adversely affects the psychological (i.e., depression, anxiety) and marital adjustment of patients and their spouses. Dyadic coping refers to how couples cope with stress. It includes positive actions like shari
Externí odkaz:
https://doaj.org/article/7fec1c70327a44b18336072f8b172693
Autor:
Wangjie Yu, Cristian Coarfa, Ananth Annapragada, Min Wang, Tej K. Pandita, Ratna Veeramachaneni, Vlad C. Sandulache, Sandra L. Grimm, Sergio Jaramillo, Michelle Ludwig, Kassidy A. Hebert, Mark D. Bonnen, Yohannes T. Ghebre, Farrah Kheradmand, David B. Corry, George Miles, Andrew G. Sikora, Shixia Huang, Dimuthu Perera, Raj K. Pandita
Publikováno v:
Oncotarget
The resistance of cancer cells to radiation-based treatment is a major clinical challenge confounding standard of care in cancer. This problem is particularly notable in many solid tumors where cancer cells are only partially responsive to radiation
Autor:
Mark D. Bonnen, Shraddha M. Dalwadi, Nabila Waheed, Danny Tran, Michelle Ludwig, Constantine Mantz, Bui Tung
Publikováno v:
Journal of Radiation Oncology. 8:329-335
For inoperable endometrial cancer (ECA) patients, definitive chemoradiation with stereotactic body radiotherapy (SBRT) boost may be an option. SBRT schedules and dose distributions approximate brachytherapy boost (BB) radiobiologic dosing, while elim
Autor:
John Bowers, Michelle Ludwig, Mihir Shukla, Walker Mainwaring, Todd A. Pezzi, Mark D. Bonnen, Ngoc Minh Pham
Publikováno v:
Clinical Breast Cancer. 19:e343-e351
Metastases to the brain occur in 10%-16% of patients with breast cancer, with incidence reportedly increasing. Historically, brain metastases (BM) have been treated with whole-brain radiation therapy (WBRT), but stereotactic radiosurgery (SRS) is an
Autor:
Min Wang, Yohannes T. Ghebre, Li Li, Mark D. Bonnen, Anil G. Jegga, Afshin Ebrahimpour, Farrah Kheradmand, S. Jyothula, Nicola A. Hanania, N. Tony Eissa, Ganesh Raghu, Ivan O. Rosas
Publikováno v:
Journal of Inflammation (London, England)
Journal of Inflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Journal of Inflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Introduction Idiopathic pulmonary fibrosis (IPF) is an orphan disease characterized by progressive loss of lung function resulting in shortness of breath and often death within 3–4 years of diagnosis. Repetitive lung injury in susceptible individua
Autor:
Timothy Wagner, Mark D. Bonnen, Pamela Myers, Michelle Ludwig, Julianna K. Bronk, Jason Bryan, Danny Tran
Publikováno v:
Journal of Radiation Oncology. 7:317-323
Different methodologies to deliver craniospinal irradiation (CSI) to patients have been implemented due to the toxicity and planning challenges associated with traditional three-dimensional conformal radiation therapy. Patient outcomes data are neede