Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mark Cranfield"'
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Metastasis is a complex process which is difficult to study and model. Experimental ingenuity is therefore essential when seeking to elucidate the biological mechanisms involved. Typically, in vitro models of metastasis have been
Externí odkaz:
https://doaj.org/article/50d04847c5c7426f883b61004c6ceb6f
Autor:
Mark Cranfield, Norma L. Hudson, H R Sawyer, Olli Ritvos, Jennifer L. Juengel, Karen L Reader, Nigel P. Groome, George H. Davis, Kenneth P. McNatty, T. Wilson, C L Moeller, Mika Laitinen, S. M. Galloway
Publikováno v:
Bioscientifica Proceedings.
The physiological mechanisms controlling ovulation rate in mammals involve a complex exchange of endocrine signals between the pituitary gland and the ovary, and a localized exchange of intraovarian hormones between the oocyte and its adjacent somati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5575a39cfd744023c09bdbb554d6e95c
https://doi.org/10.1530/biosciprocs.5.025
https://doi.org/10.1530/biosciprocs.5.025
Publikováno v:
Translational Research. 158:334-343
Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353fb5b75e0a2a29679bcbe2e7de497c
https://doi.org/10.1016/j.trsl.2011.07.009
https://doi.org/10.1016/j.trsl.2011.07.009
Autor:
Axel P. N. Themmen, M. Appasamy, Shanthi Muttukrishna, Jenny A. Visser, Jemma Johns, Nigel P. Groome, Mark Cranfield, Ahmed Al-Qahtani
Publikováno v:
Clinical Endocrinology, 63(3), 267-273. Wiley-Blackwell Publishing Ltd
Summary Background and objective Recent studies have found anti-Mullerian hormone (AMH) to be a potentially important marker for the assessment of ovarian reserve and prediction of the success of in vitro fertilization (IVF) treatment. The objectives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dec6d0c3a0e2dc8cee606c1b3a0bcd0
https://doi.org/10.1111/j.1365-2265.2005.02336.x
https://doi.org/10.1111/j.1365-2265.2005.02336.x
Autor:
Elspeth Gold, Jean S. Fleming, Nigel P. Groome, Antony M. Wheatley, Sally Louise Mellor, Gail P. Risbridger, Xing-Yi Zhang, Mark Cranfield
Publikováno v:
Journal of Molecular Endocrinology. 34:505-515
The mRNA expression of two activin growth factor subunits (βA- and βC-activin), activin receptor subunits (ActRIIA, ActRIIB) and the activin-binding protein follistatin, and peptide expression of βA-activin and βC-activin subunits, were examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017fdeb4e689e22053f3522b15c90231
https://doi.org/10.1677/jme.1.01657
https://doi.org/10.1677/jme.1.01657
Autor:
Robert B. Gilchrist, F. Amato, Hilkka Lankinen, David G. Mottershead, N. P. Groome, Lesley J. Ritter, Mark Cranfield, Luke Jeffery, S. Myllymaa, Noora Kaivo-Oja, Olli Ritvos, S. J. Scott
Publikováno v:
Biology of Reproduction. 71:732-739
Paracrine factors secreted by oocytes play a pivotal role in promoting early ovarian follicle growth and in defining a morphogenic gradient in antral follicles, yet the exact identities of these oocyte factors remain unknown. This study was conducted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacc9e3e710d301f3828e80ff4d38932
https://doi.org/10.1095/biolreprod.104.028852
https://doi.org/10.1095/biolreprod.104.028852
Autor:
Jean S. Fleming, Mark Cranfield, Gail P. Risbridger, Moira K O'Bryan, Sally Louise Mellor, Nigel P. Groome, Elspeth Gold
Publikováno v:
Molecular and Cellular Endocrinology. 222:61-69
betaC-activin expression was assessed in rat tissues, using reverse transcription and real-time polymerase chain reaction, Western blotting and immunohistochemistry with a specific monoclonal antibody. betaC-activin mRNA was predominantly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f58b64be22a7a366e7fe6cf8b70e1c9
https://doi.org/10.1016/j.mce.2004.05.007
https://doi.org/10.1016/j.mce.2004.05.007
Autor:
Jenny A. Visser, Axel P. N. Themmen, Mark Cranfield, Nigel P. Groome, Christien Weenen, Piet Kramer, Bart C.J.M. Fauser, Anne R.M. von Bergh, Joop S.E. Laven
Publikováno v:
Molecular Human Reproduction, 10(2), 77-83. Oxford University Press
Anti-Mullerian hormone (AMH) is a member of the transforming growth factor-b superfamily, which plays an important role in both ovarian primordial follicle recruitment and dominant follicle selection in mice. However, the role of AMH in folliculo- ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811ea5b28aeaf8b69ca8e4b661243fdc
https://hdl.handle.net/1765/69117
https://hdl.handle.net/1765/69117
Activin βC-Subunit Heterodimers Provide a New Mechanism of Regulating Activin Levels in the Prostate
Autor:
Sally Louise Mellor, Nigel P. Groome, Emma M A Ball, Jacqueline F Schmitt, Gail P. Risbridger, David James Phillips, Mark Cranfield, Jean François Ethier, Anne E O'Connor
Publikováno v:
Endocrinology. 144:4410-4419
Activins are formed by dimerization of beta-subunits and, as members of the TGF-beta superfamily, have diverse roles as potent growth and differentiation factors. As the biological function of the activin C homodimer (betaC-betaC) is unknown, we soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc38c4bd7b3d459895c3a26dde6e2e2c
https://doi.org/10.1210/en.2003-0225
https://doi.org/10.1210/en.2003-0225
Autor:
Mark Cranfield, Aaron J. W. Hsueh, Noora Kaivo-Oja, Vesa M. Olkkonen, Nigel P. Groome, Ursula A. Vitt, Peter ten Dijke, Aristidis Moustakas, Jonas Bondestam, Masaru Hayashi, Janne P. Kallio, Kaisa Vuojolainen, Janne Koskimies, Olli Ritvos, Meerit Kämäräinen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:755-762
The TGF beta family member growth differentiation factor-9 (GDF-9) is an oocyte-derived factor that is essential for mammalian ovarian folliculogenesis. GDF-9 mRNAs have been shown to be expressed in the human ovarian follicle from the primary follic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff1c596733ea8818ac43f369d91d36a
https://doi.org/10.1210/jc.2002-021317
https://doi.org/10.1210/jc.2002-021317