Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Mark Cline"'
[18F]KS1, a novel ascorbate-based ligand images ROS in tumor models of rodents and nonhuman primates
Autor:
Naresh Damuka, Nagaraju Bashetti, Akiva Mintz, Avinash H. Bansode, Mack Miller, Ivan Krizan, Cristina Furdui, Bhuvanachandra Bhoopal, Krishna Kumar Gollapelli, JV Shanmukha Kumar, Gagan Deep, Greg Dugan, Mark Cline, Kiran Kumar Solingapuram Sai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113937- (2022)
Over production of reactive oxygen species (ROS) caused by altered redox regulation of signaling pathways is common in many types of cancers. While PET imaging is recognized as the standard tool for cancer imaging, there are no clinically-approved PE
Externí odkaz:
https://doaj.org/article/9037725abf044ab3a4b3c63fe778673b
Autor:
Maurizio Ceppi, Bruno Gomes, Michael Hettich, Simon Deycmar, Brendan Johnson, Declan Ryan, William Sills, David Caudell, Greg Dugan, Kiran Solingapuram Sai, Mark Cline
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/dfa3db68ec044eb7968fc934089d8011
Autor:
Isabel R. Barnet, Shannon R. Emerzian, Ramina Behzad, Daniel J. Brooks, Trinity Tedtsen, Marcela Granados, Sun Park, Joseph Moore, John D. Olson, Lamya Karim, Mary L. Bouxsein, J. Mark Cline, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Exposure to ionizing radiation for oncological therapy increases the risk for late-onset fractures in survivors. However, the effects of total body irradiation (TBI) on adult bone are not well-characterized. The primary aim of this study was
Externí odkaz:
https://doaj.org/article/df3ebdabc72b4be6b523528734f4c0e3
Autor:
Karthik Kanagaraj, Michelle A. Phillippi, Elizabeth H. Ober, Igor Shuryak, Norman J. Kleiman, John Olson, George Schaaf, J. Mark Cline, Helen C. Turner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract There are currently no available FDA-cleared biodosimetry tools for rapid and accurate assessment of absorbed radiation dose following a radiation/nuclear incident. Previously we developed a protein biomarker-based FAST-DOSE bioassay system
Externí odkaz:
https://doaj.org/article/54ce1567c9eb483a953a551bb96d2cf9
Autor:
Martin Widschwendter, Matthew Burnell, Lindsay Fraser, Adam N. Rosenthal, Sue Philpott, Daniel Reisel, Louis Dubeau, Mark Cline, Yang Pan, Ping-Cheng Yi, D. Gareth Evans, Ian J. Jacobs, Usha Menon, Charles E. Wood, William C. Dougall
Publikováno v:
EBioMedicine, Vol 2, Iss 10, Pp 1331-1339 (2015)
Breast cancer development in BRCA1/2 mutation carriers is a net consequence of cell-autonomous and cell nonautonomous factors which may serve as excellent targets for cancer prevention. In light of our previous data we sought to investigate the conse
Externí odkaz:
https://doaj.org/article/c1a750bb46dc475e933cb1495b528c24
Autor:
Manal Zabalawi, Manish Bharadwaj, Heather Horton, Mark Cline, Mark Willingham, Michael J. Thomas, Mary G. Sorci-Thomas
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 1, Pp 52-65 (2007)
Diet-fed low density lipoprotein receptor-deficient/apolipoprotein A-I-deficient (LDLr−/−, apoA-I−/−) mice accumulate a 10-fold greater mass of cholesterol in their skin despite a 1.5- to 2-fold lower plasma cholesterol concentration compared
Externí odkaz:
https://doaj.org/article/cf2baeb74406423ca07860fa4fc89c28
Autor:
Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. Romero, Francois J. Villinger, Armando G. Burgos, Hannah C. Ainsworth, Lance D. Miller, Gregory A. Hawkins, Jeff W. Chou, Bruno Gomes, Michael Hettich, Maurizio Ceppi, Jehad Charo, J. Mark Cline
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the comparative molecular
Externí odkaz:
https://doaj.org/article/30efa148afbb4e31af85e684a6b0f213
Autor:
Omar L. Nelson, Rebecca Rosales, Jane Turbov, Larry G Thaete, Gayathriy Balamayooran, J Mark Cline, J. Wesley Pike, Gustavo C. Rodriguez
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3318 (2024)
Epidemiological and observational studies suggest that vitamin D has potential for the chemoprevention of ovarian cancer. The anticancer effect of vitamin D in the fallopian tube epithelium (FTE), which is now thought to harbor the precursor cells fo
Externí odkaz:
https://doaj.org/article/7d46663523c24a15be862fbd7b0d9cf6
Autor:
Brendan J. Johnson, Megan E. Lipford, Richard A. Barcus, John D. Olson, George W. Schaaf, Rachel N. Andrews, Jeongchul Kim, Greg O. Dugan, Simon Deycmar, Colin A. Reed, Christopher T. Whitlow, J. Mark Cline
Publikováno v:
NeuroImage, Vol 285, Iss , Pp 120491- (2024)
Cerebrovascular reactivity (CVR) is a measure of cerebral small vessels’ ability to respond to changes in metabolic demand and can be quantified using magnetic resonance imaging (MRI) coupled with a vasoactive stimulus. Reduced CVR occurs with neur
Externí odkaz:
https://doaj.org/article/5389fffff8fd477487509fbadeb757c6
Autor:
Simon Deycmar, George W Schaaf, Brendan J Johnson, J Daniel Bourland, James D Ververs, Christopher T Whitlow, J Mark Cline
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6445b5847ba84b179d1a9a01faea0a62