Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark Chilvers"'
Autor:
Jiafen Gong, Gengming He, Cheng Wang, Claire Bartlett, Naim Panjwani, Scott Mastromatteo, Fan Lin, Katherine Keenan, Julie Avolio, Anat Halevy, Michelle Shaw, Mohsen Esmaeili, Guillaume Côté-Maurais, Damien Adam, Stéphanie Bégin, Candice Bjornson, Mark Chilvers, Joe Reisman, April Price, Michael Parkins, Richard van Wylick, Yves Berthiaume, Lara Bilodeau, Dimas Mateos-Corral, Daniel Hughes, Mary J. Smith, Nancy Morrison, Janna Brusky, Elizabeth Tullis, Anne L. Stephenson, Bradley S. Quon, Pearce Wilcox, Winnie M. Leung, Melinda Solomon, Lei Sun, Emmanuelle Brochiero, Theo J. Moraes, Tanja Gonska, Felix Ratjen, Johanna M. Rommens, Lisa J. Strug
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Over 400 variants in the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) are CF-causing. CFTR modulators target variants to improve lung function, but marked variability in response exists and current therapies do not address
Externí odkaz:
https://doaj.org/article/c9a883e6061748a2ad1bb0acfad420a2
Autor:
Scott Mastromatteo, Angela Chen, Jiafen Gong, Fan Lin, Bhooma Thiruvahindrapuram, Wilson W.L. Sung, Joe Whitney, Zhuozhi Wang, Rohan V. Patel, Katherine Keenan, Anat Halevy, Naim Panjwani, Julie Avolio, Cheng Wang, Guillaume Côté-Maurais, Stéphanie Bégin, Damien Adam, Emmanuelle Brochiero, Candice Bjornson, Mark Chilvers, April Price, Michael Parkins, Richard van Wylick, Dimas Mateos-Corral, Daniel Hughes, Mary Jane Smith, Nancy Morrison, Elizabeth Tullis, Anne L. Stephenson, Pearce Wilcox, Bradley S. Quon, Winnie M. Leung, Melinda Solomon, Lei Sun, Felix Ratjen, Lisa J. Strug
Publikováno v:
HGG Advances, Vol 4, Iss 1, Pp 100156- (2023)
Summary: Phasing of heterozygous alleles is critical for interpretation of cis-effects of disease-relevant variation. We sequenced 477 individuals with cystic fibrosis (CF) using linked-read sequencing, which display an average phase block N50 of 4.3
Externí odkaz:
https://doaj.org/article/000a1d3c634e4c91b0e728e58acc8bdb
Autor:
Constantina Boikos, Jesse Papenburg, Christine Martineau, Lawrence Joseph, David Scheifele, Mark Chilvers, Larry C. Lands, Gaston De Serres, Caroline Quach
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 6, Pp 1254-1260 (2017)
Background: The objective of this study was to explore the effects of viral co-detection in individuals recently vaccinated with the live-attenuated intranasal influenza virus vaccine (LAIV) on the detection of influenza RNA. Methods: Before the 2013
Externí odkaz:
https://doaj.org/article/6ed389c80d95473fb7245e9c95b7538b
Autor:
Graham Sinclair, Vanessa McMahon, Amy Schellenberg, Tanya N. Nelson, Mark Chilvers, Hilary Vallance
Publikováno v:
International Journal of Neonatal Screening, Vol 6, Iss 2, p 46 (2020)
Newborn screening for Cystic Fibrosis has been implemented in most programs worldwide, but the approach used varies, including combinations of immunoreactive trypsinogen (IRT) and CFTR mutation analysis on one or more specimens. The British Columbia
Externí odkaz:
https://doaj.org/article/8a4bdc77f26d4552851773d97957359c
Autor:
Scott Mastromatteo, Angela Chen, Jiafen Gong, Fan Lin, Bhooma Thiruvahindrapuram, Wilson WL Sung, Joe Whitney, Zhuozhi Wang, Rohan V Patel, Katherine Keenan, Anat Halevy, Naim Panjwani, Julie Avolio, Cheng Wang, Guillaume Côté-Maurais, Stéphanie Bégin, Damien Adam, Emmanuelle Brochiero, Candice Bjornson, Mark Chilvers, April Price, Michael Parkins, Richard van Wylick, Dimas Mateos-Corral, Daniel Hughes, Mary Jane Smith, Nancy Morrison, Elizabeth Tullis, Anne L Stephenson, Pearce Wilcox, Bradley S Quon, Winnie M Leung, Melinda Solomon, Lei Sun, Felix Ratjen, Lisa J Strug
Phasing of heterozygous alleles is critical for interpretation of cis-effects of disease-relevant variation. For population studies, phase is often inferred from external data but read-based phasing approaches that span long genomic distances would b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2bee7a4d3021ec41ff4c5915cdb67a8
https://doi.org/10.1101/2022.03.28.486092
https://doi.org/10.1101/2022.03.28.486092
Autor:
Gregory S. Sawicki, Mark Chilvers, John McNamara, Lutz Naehrlich, Clare Saunders, Isabelle Sermet-Gaudelus, Claire E. Wainwright, Neil Ahluwalia, Daniel Campbell, R. Scott Harris, Hildegarde Paz-Diaz, Judy L. Shih, Jane C. Davies
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 21(4)
Two previous Phase 3 studies ("parent studies") showed that tezacaftor/ivacaftor was generally safe and efficacious for up to 24 weeks in children 6 through 11 years of age with cystic fibrosis (CF) and F508del/F508del (F/F) or F508del/residual funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e23409bd94458716b3142f66fd446be
https://pubmed.ncbi.nlm.nih.gov/35190292
https://pubmed.ncbi.nlm.nih.gov/35190292
Publikováno v:
Chest. 152(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6538ec1d8c9a0994c851888be8d0cb97
https://pubmed.ncbi.nlm.nih.gov/29223261
https://pubmed.ncbi.nlm.nih.gov/29223261
Publikováno v:
Thorax. 55:314-317
BACKGROUND—The aim of this study was to determine the relationship of the power and recovery stroke of respiratory cilia using digital high speed video imaging. Beat frequency measurements made using digital high speed video were also compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5506cb7ca53482fb1ffc9ee0a18cbd
https://doi.org/10.1136/thorax.55.4.314
https://doi.org/10.1136/thorax.55.4.314
Publikováno v:
Washington Post, The. 08/28/2018.