Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark C. Grier"'
Autor:
Adrienne Mottis, Terytty Y. Li, Gaby El Alam, Alexis Rapin, Elena Katsyuba, David Liaskos, Davide D’Amico, Nicola L. Harris, Mark C. Grier, Laurent Mouchiroud, Mark L. Nelson, Johan Auwerx
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Mitohormesis defines the increase in fitness mediated by adaptive responses to mild mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on eukaryotic cel
Externí odkaz:
https://doaj.org/article/640bce408e454dcb9f479983b78136ee
Autor:
Eric J. Bryan, Hye Yeon Sagong, Ajit K. Parhi, Mark C. Grier, Jacques Y. Roberge, Edmond J. LaVoie, Daniel S. Pilch
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 693 (2022)
The emergence of multi-drug-resistant Gram-negative pathogens highlights an urgent clinical need to explore and develop new antibiotics with novel antibacterial targets. MreB is a promising antibacterial target that functions as an essential elongaso
Externí odkaz:
https://doaj.org/article/f8ac5228aca5430cb41dd1a89b48c18b
Autor:
Graeme Griffin, Anu Mahadevan, Raj K. Razdan, Mark C. Grier, Caroline E. Bass, Billy R. Martin
Publikováno v:
Pharmacology Biochemistry and Behavior. 74:31-40
The central cannabinoid receptor (CB1) antagonist, SR-141716A, has been used extensively to ascertain that cannabinoids interact with the CB1 receptor. SR-141716A has been shown to produce effects opposite of cannabinoids when administered alone. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adde45f566ff6b205e70a9a6cc487cd3
https://doi.org/10.1016/s0091-3057(02)00945-0
https://doi.org/10.1016/s0091-3057(02)00945-0
Autor:
Graeme Griffin, Ines Brandi, Mark C. Grier, William Williams, Raj K. Razdan, Sanjitha Kulasegram, Anu Mahadevan, Billy R. Martin, Vincenzo Di Marzo, Luciano De Petrocellis, Tiziana Bisogno
Publikováno v:
The Journal of pharmacology and experimental therapeutics
300 (2002): 984–991. doi:10.1124/jpet.300.3.984
info:cnr-pdr/source/autori:Di Marzo V., Griffin G., De Petrocellis L., Brandi I., Bisogno T., Williams W., Grier M.C., Kulasegram S., Mahadevan A., Razdan R.K., Martin B.R./titolo:A structure%2Factivity relationship study on arvanil, an endocannabinoid and vanilloid hybrid/doi:10.1124%2Fjpet.300.3.984/rivista:The Journal of pharmacology and experimental therapeutics (Print)/anno:2002/pagina_da:984/pagina_a:991/intervallo_pagine:984–991/volume:300
300 (2002): 984–991. doi:10.1124/jpet.300.3.984
info:cnr-pdr/source/autori:Di Marzo V., Griffin G., De Petrocellis L., Brandi I., Bisogno T., Williams W., Grier M.C., Kulasegram S., Mahadevan A., Razdan R.K., Martin B.R./titolo:A structure%2Factivity relationship study on arvanil, an endocannabinoid and vanilloid hybrid/doi:10.1124%2Fjpet.300.3.984/rivista:The Journal of pharmacology and experimental therapeutics (Print)/anno:2002/pagina_da:984/pagina_a:991/intervallo_pagine:984–991/volume:300
Arvanil, a structural "hybrid" between the endogenous cannabinoid CB1 receptor ligand anandamide and capsaicin, is a potent agonist for the capsaicin receptor VR1 (vanilloid receptor type 1), inhibits the anandamide membrane transporter (AMT), and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb814cca8f7f938415822325365da4b2
https://doi.org/10.1124/jpet.300.3.984
https://doi.org/10.1124/jpet.300.3.984
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdca40dcef4e3d56ad61216ed3d343f7
https://doi.org/10.1002/chin.199412045
https://doi.org/10.1002/chin.199412045
Autor:
Gary E. Keck, Mark C. Grier
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fdecf0b7ae17e77974c7a020dcf7d52
https://doi.org/10.1002/chin.200003131
https://doi.org/10.1002/chin.200003131
Autor:
Gary E. Keck, Mark C. Grier
Publikováno v:
Synlett. 1999:1657-1659
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::116369c874fa99089742ac53f316c6c4
https://doi.org/10.1055/s-1999-2913
https://doi.org/10.1055/s-1999-2913
Publikováno v:
The Journal of Organic Chemistry. 58:6543-6544
Enantioselective additions of methallylstannanes to representative aldehydes with four chiral Lewis acid systems afford ee's of 84-99% using 10 mol % of catalyst. In one case, use of (R)-BINOL of 50% ee gave product with 88% ee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b279d8c7446009635890a2228f4966
https://doi.org/10.1021/jo00076a005
https://doi.org/10.1021/jo00076a005
Autor:
Oak K. Kim, Lynne K. Garrity-Ryan, Victoria J. Bartlett, Mark C. Grier, Atul K. Verma, Gabriel Medjanis, Janice E. Donatelli, Ann B. Macone, S. Ken Tanaka, Stuart B. Levy, Michael N. Alekshun
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 18, p5626-5634, 9p