Colorful protein-based fluorescent probes for collagen imaging.

Autor: Stijn J A Aper, Ariane C C van Spreeuwel, Mark C van Turnhout, Ardjan J van der Linden, Pascal A Pieters, Nick L L van der Zon, Sander L de la Rambelje, Carlijn V C Bouten, Maarten Merkx

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e114983 (2014)

Real-time visualization of collagen is important in studies on tissue formation and remodeling in the research fields of developmental biology and tissue engineering. Our group has previously reported on a fluorescent probe for the specific imaging o

Externí odkaz: https://doaj.org/article/a138b360d3034db2859c825016277bb5

An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip

Autor: Nikita Subedi, Laura C. Van Eyndhoven, Ayla M. Hokke, Lars Houben, Mark C. Van Turnhout, Carlijn V. C. Bouten, Klaus Eyer, Jurjen Tel

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged end-point measures, crucial insights on the dynamics and heterogeneity of effector

Externí odkaz: https://doaj.org/article/87160ca70d764539bc92b8e660f8164f

An automated real-time microfluidic platform to probe single NK cell heterogeneity and cytotoxicity on-chip

Autor: Ayla M. Hokke, Klaus Eyer, Jurjen Tel, Nikita Subedi, Carlijn V. C. Bouten, Laura C. Van Eyndhoven, Lars Houben, Mark C. van Turnhout

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, 11(1):17084. Nature Publishing Group
Scientific Reports, 11 (1)

Cytotoxicity is a vital effector mechanism used by immune cells to combat pathogens and cancer cells. While conventional cytotoxicity assays rely on averaged end-point measures, crucial insights on the dynamics and heterogeneity of effector and targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e94cdc43ad32c9c2cab3024b5e92a9
http://europepmc.org/articles/PMC8385055

Cellular Contact Guidance Emerges from Gap Avoidance

Autor: Vikram Deshpande, Siamak Soleymani Shishvan, Antonetta B.C. Buskermolen, Mark C. van Turnhout, Carlijn V. C. Bouten, Nicholas A. Kurniawan, S Sandra Loerakker, Tommaso Ristori, Dylan Mostert

Publikováno v: Cell Reports Physical Science
Cell Reports Physical Science, Vol 1, Iss 5, Pp 100055-(2020)
Cell Reports. Physical Science, 1(5):100055. Cell Press
Cell Reports. Physical Science

Summary In the presence of anisotropic biochemical or topographical patterns, cells tend to align in the direction of these cues—a widely reported phenomenon known as “contact guidance.” To investigate the origins of contact guidance, here, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c351c4ad434ff0ffd3302cbbaafd181
https://doi.org/10.1016/j.xcrp.2020.100055

MRI based 3D finite element modelling to investigate deep tissue injury

Autor: Kevin M. Moerman, Jules L. Nelissen, Dan L. Bader, Cees W. J. Oomens, Gustav J. Strijkers, Mark C. van Turnhout, Willeke A. Traa, Aart J. Nederveen

Publikováno v: Computer Methods in Biomechanics and Biomedical Engineering, 21(14), 760-769. Informa Healthcare
Computer methods in biomechanics and biomedical engineering, 21(14), 760-769. Informa Healthcare

Pressure ulcers occur due to sustained mechanical loading. Deep tissue injury is a severe type of pressure ulcer, which is believed to originate in subcutaneous tissues adjacent to bony prominences. In previous experimental-numerical studies the rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a897458ad1b8f6de8d7e597a6d0615d7
https://research.tue.nl/nl/publications/cdfb2216-bdda-46ab-9318-eee47b3569d2