Mass Spectrometry

Autor: Mark C. Parkin, Alan Brailsford

Publikováno v: Analytical Techniques in Forensic Science. :219-265

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9014e53e93c22f8ab68ecf670f0bbf83
https://doi.org/10.1002/9781119373421.ch10

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

Autor: Claire George, Paul I. Dargan, Agostino Cilibrizzi, Andrew T. Kicman, Vincenzo Abbate, Joanna Czerwinska, Mark C. Parkin

Publikováno v: Pharmaceuticals, Vol 14, Iss 5, p 5 (2021)
Czerwinska, J, Parkin, M C, Cilibrizzi, A, George, C, Kicman, A T, Dargan, P I & Abbate, V 2020, ' Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers ', Pharmaceuticals, vol. 14, no. 1, 5 . https://doi.org/10.3390/ph14010005
Pharmaceuticals
Volume 14
Issue 1

Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(&minus
)-mephedrone. There are some preliminary data suggesting that the enantiomers of mephedro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61577c3ecadf1a23075b40347c81c80
https://www.mdpi.com/1424-8247/14/1/5

Pharmacokinetics of Mephedrone and Its Metabolites in Whole Blood and Plasma after Controlled Intranasal Administration to Healthy Human Volunteers

Autor: Vincenzo Abbate, Andrew T. Kicman, Joanna Czerwinska, Paul I. Dargan, Claire George, Mark C. Parkin

Publikováno v: Journal of analytical toxicology. 45(7)

Mephedrone is a popular synthetic cathinone, known for its psychostimulant effects. At present, there is no data available on the pharmacokinetics of mephedrone and its metabolites in concurrently collected whole blood and plasma samples after a cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a8f41ad4bd708887e47897ad4481b
https://pubmed.ncbi.nlm.nih.gov/32986113

Quantification of cocaine and cocaine metabolites in dried blood spots from a controlled administration study using liquid chromatography–tandem mass spectrometry

Autor: Eleanor Menzies, David M. Wood, Andrew T. Kicman, John R. H. Archer, Lars Ambach, Mark C. Parkin, Christophe P. Stove, Paul I. Dargan

Publikováno v: Drug Testing and Analysis. 11:709-720

Cocaine is a common illicit stimulant and is mainly metabolized by hydrolysis to benzoylecgonine (BE) and ecgonine methyl ester (EME), but also to minor metabolites like norcocaine, or hydroxy-BE. When ethanol is present, cocaethylene is formed. Drie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd419cac50090001bcdafc86d54407bb
https://doi.org/10.1002/dta.2537

Improved determination of femtogram-level organic explosives in multiple matrices using dual-sorbent solid phase extraction and liquid chromatography-high resolution accurate mass spectrometry

Autor: Matthew S. Beardah, Mark C. Parkin, Leon Barron, Dermot Brabazon, Michael P. O'Donnell, Rachel C. Irlam

Publikováno v: Irlam, R C, Parkin, M C, Brabazon, D P, Beardah, M S, O'Donnell, M & Barron, L P 2019, ' Improved determination of femtogram-level organic explosives in multiple matrices using dual-sorbent solid phase extraction and liquid chromatography-high resolution accurate mass spectrometry ', TALANTA, vol. 203, pp. 65-76 . https://doi.org/10.1016/j.talanta.2019.05.047

Identification and trace quantification of multiple explosives residues, their precursors and transformation products in complex samples remains very challenging. For solid phase extraction (SPE) and liquid chromatography-high resolution accurate mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c6a8242326e6462a72e7e421298ebc
https://kclpure.kcl.ac.uk/en/publications/baafa1b1-a58f-4774-831e-42698e1ec10a