Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Mark Burton"'
Autor:
Ines Block, Mark Burton, Kristina P. Sørensen, Martin J. Larsen, Thi T. N. Do, Martin Bak, Søren Cold, Mads Thomassen, Qihua Tan, Torben A. Kruse
Publikováno v:
Cancer Medicine, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Background Current clinical markers overestimate the recurrence risk in many lymph node negative (LNN) breast cancer (BC) patients such that a majority of these low‐risk patients unnecessarily receive systemic treatments. We tested if diff
Externí odkaz:
https://doaj.org/article/f87c4fa2f826470a8dde22579f310ce2
Autor:
Charlotte Harken Jensen, Rikke Helin Johnsen, Tilde Eskildsen, Christina Baun, Ditte Gry Ellman, Shu Fang, Sara Thornby Bak, Svend Hvidsten, Lars Allan Larsen, Ann Mari Rosager, Lars Peter Riber, Mikael Schneider, Jo De Mey, Mads Thomassen, Mark Burton, Shizuka Uchida, Jorge Laborda, Ditte Caroline Andersen
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background Heart failure due to myocardial infarction (MI) involves fibrosis driven by epicardium‐derived cells (EPDCs) and cardiac fibroblasts, but strategies to inhibit and provide cardio‐protection remains poor. The imprinted gene, no
Externí odkaz:
https://doaj.org/article/8159e282c4c94511948c59dd2e803759
Autor:
Pratibha Dhumale, Jakob Vennike Nielsen, Anne Cathrine Schmidt Hansen, Mark Burton, Hans Christian Beck, Mads Gustaf Jørgensen, Navid Mohamadpour Toyserkani, Martha Kirstine Haahr, Sabrina Toft Hansen, Lars Lund, Mads Thomassen, Jens Ahm Sørensen, Ditte Caroline Andersen, Charlotte Harken Jensen, Søren Paludan Sheikh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Cellular heterogeneity represents a major challenge for regenerative treatment using freshly isolated Adipose Derived Regenerative Cells (ADRCs). Emerging data suggest superior efficacy of ADRCs as compared to the ex vivo expanded and more h
Externí odkaz:
https://doaj.org/article/8349d1f1a861482c933e74589114bbd7
Autor:
Soojung Lee, Nicolai J. Toft, Trine V. Axelsen, Maria Sofia Espejo, Tina M. Pedersen, Marco Mele, Helene L. Pedersen, Eva Balling, Tonje Johansen, Mark Burton, Mads Thomassen, Pernille Vahl, Peer Christiansen, Ebbe Boedtkjer
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-27 (2023)
Abstract Background Carbonic anhydrases catalyze CO2/HCO3 – buffer reactions with implications for effective H+ mobility, pH dynamics, and cellular acid–base sensing. Yet, the integrated consequences of carbonic anhydrases for cancer and stromal
Externí odkaz:
https://doaj.org/article/43eb9c61abb047289a64eb505c8ecf73
Autor:
Reza Khorooshi, Joanna Marczynska, Ruthe Storgaard Dieu, Vian Wais, Christian Rønn Hansen, Stephanie Kavan, Mads Thomassen, Mark Burton, Torben Kruse, Gill A. Webster, Trevor Owens
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract There is great interest in understanding how the central nervous system (CNS) communicates with the immune system for recruitment of protective responses. Infiltrating phagocytic monocytes and granulocytes are implicated in neuroinflammation
Externí odkaz:
https://doaj.org/article/d60c0ab7320849308350694b265d8a2d
Autor:
Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Compared to 25 WM controls, 6713 ou
Externí odkaz:
https://doaj.org/article/d6c83e801176419788562e1f9dd05599
Autor:
Nicolai J Toft, Trine V Axelsen, Helene L Pedersen, Marco Mele, Mark Burton, Eva Balling, Tonje Johansen, Mads Thomassen, Peer M Christiansen, Ebbe Boedtkjer
Publikováno v:
eLife, Vol 10 (2021)
Breast cancer heterogeneity in histology and molecular subtype influences metabolic and proliferative activity and hence the acid load on cancer cells. We hypothesized that acid-base transporters and intracellular pH (pHi) dynamics contribute inter-i
Externí odkaz:
https://doaj.org/article/d654619d0e9a42edb5ad6ac158c69716
Autor:
Ruthe Storgaard Dieu, Vian Wais, Michael Zaucha Sørensen, Joanna Marczynska, Magdalena Dubik, Stephanie Kavan, Mads Thomassen, Mark Burton, Torben Kruse, Reza Khorooshi, Trevor Owens
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Innate receptors, including Toll like receptors (TLRs), are implicated in pathogenesis of CNS inflammatory diseases such as multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). TLR response to pathogens or end
Externí odkaz:
https://doaj.org/article/b64a2d79216d4c6dbb396a2f748f9b86
Autor:
Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract The heterogeneity of multiple sclerosis is reflected by dynamic changes of different lesion types in the brain white matter (WM). To identify potential drivers of this process, we RNA-sequenced 73 WM areas from patients with progressive MS (
Externí odkaz:
https://doaj.org/article/852aa60c33054bdd98dadf9bebfe5b2d
Autor:
Thi T. N. Do, Ines Block, Mark Burton, Kristina P. Sørensen, Martin J. Larsen, Martin Bak, Søren Cold, Mads Thomassen, Qihua Tan, Torben A. Kruse
Publikováno v:
Cancers, Vol 13, Iss 19, p 4907 (2021)
Several gene expression signatures based on mRNAs and a few based on long non-coding RNAs (lncRNAs) have been developed to provide prognostic information beyond clinical evaluation in breast cancer (BC). However, the comparison of such signatures for
Externí odkaz:
https://doaj.org/article/39ea0a8419944fde9a6f437ca977eccd