Výsledky vyhledávání - "Mark Barkhuizen"

Akademický článek

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia.

Autor: Jennifer Cnops, Carl De Trez, Benoit Stijlemans, Jiri Keirsse, Florence Kauffmann, Mark Barkhuizen, Roanne Keeton, Louis Boon, Frank Brombacher, Stefan Magez

Publikováno v: PLoS Pathogens, Vol 11, Iss 6, p e1004964 (2015)

African trypanosomes are the causative agents of Human African Trypanosomosis (HAT/Sleeping Sickness) and Animal African Trypanosomosis (AAT/Nagana). A common hallmark of African trypanosome infections is inflammation. In murine trypanosomosis, the o

Externí odkaz: https://doaj.org/article/341592b48dc444e99d9cf83031d20148

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IL-4Rα-responsive smooth muscle cells increase intestinal hypercontractility and contribute to resistance during acute Schistosomiasis

Autor: Tiroyaone M Brombacher, Frank Brombacher, Lauriston Kellaway, Benjamin G Dewals, Dhirendra Govender, Reece Gerrad Marillier, William Gc Horsnell, Mark Barkhuizen, Mosiuoa Leeto

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G943-G951

Interleukin-(IL)-4 and IL-13 signal through heterodimeric receptors containing a common IL-4 receptor-α (IL-4Rα) subunit, which is important for protection against helminth infections, including schistosomiasis. Previous studies demonstrated import

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ce2b5c42c2a9309c59cc51923987a8
https://doi.org/10.1152/ajpgi.00321.2009

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Interleukin‐12p70 Deficiency Increases Survival and Diminishes Pathology inTrypanosoma congolenseInfection

Autor: Mark Barkhuizen, Stefan Magez, Bernhard Ryffel, Frank Brombacher

Publikováno v: Vrije Universiteit Brussel
Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2008, 198 (9), pp.1284-91. ⟨10.1086/592048⟩

To determine the immunological role played by interleukin (IL)–12 family members in Trypanosoma congolense infection, IL-12p35 / , IL-12p40 / , and IL-12p35 / /p40 / mice were used. While the latter 2 strains lack all IL-12 homologues, IL-12p35 / m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b77284bcac73003290f4072132784e
https://doi.org/10.1086/592048

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Interleukin-12p70-dependent interferon-gamma production is crucial for resistance in African Trypanosomiasis

Autor: Mark Barkhuizen, stefan magez, Atkinson, Robert A., Frank Brombacher

Publikováno v: Vrije Universiteit Brussel

African trypanosomiasis encompasses diseases caused by pathogenic trypanosomes, infecting both humans and animals. In the present article, we dissected the possible role of members of the interleukin (IL)-12 family during infection with Trypanosoma b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2f2e9496f5ce42e61284d9940f2e83e6
https://biblio.vub.ac.be/vubir/interleukin12p70dependent-interferongamma-production-is-crucial-for-resistance-in-african-trypanosomiasis(96b3d5a1-51f0-4860-b8f3-62c26ee0b2b3).html

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Interleukin-12p70-dependent interferon- gamma production is crucial for resistance in African trypanosomiasis

Autor: Robert A. Atkinson, Frank Brombacher, Stefan Magez, Mark Barkhuizen

Publikováno v: The Journal of infectious diseases. 196(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87307557a42784def861067bd4d633a
https://pubmed.ncbi.nlm.nih.gov/17955445

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NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

Autor: Carl De Trez, Florence Kauffmann, Mark Barkhuizen, Stefan Magez, Jiri Keirsse, Jennifer Cnops, Louis Boon, Roanne Keeton, Benoit Stijlemans, Frank Brombacher

Publikováno v: PLoS Pathogens
PLoS One
PLoS Pathogens, Vol 11, Iss 6, p e1004964 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7262892d3cae23a343c7a18fd9332c46
https://doi.org/10.1371/journal.ppat.1004964

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The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent

Autor: Valérie Quesniaux, Patrick De Baetselier, Michael Drennan, Stefan Magez, Frank Brombacher, Benoit Stijlemans, Bernhard Ryffel, Jan Van Den Abbeele, Mark Barkhuizen

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2005, 175, pp.2501-9
Vrije Universiteit Brussel
Scopus-Elsevier

The initial host response toward the extracellular parasite Trypanosoma brucei is characterized by the early release of inflammatory mediators associated with a type 1 immune response. In this study, we show that this inflammatory response is depende

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c3406de6bb8e3bf51b7d3dcd106dc7
https://hal.archives-ouvertes.fr/hal-00094314

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Ethnic differences in allelic associations of the interleukin-1 gene cluster in South African patients with inflammatory bowel disease (IBD) and in control individuals

Autor: Ernest Song, John B. Dewar, Visva Pillay, Mark Barkhuizen, Obedy Mwantembe, Marie-Christine Gaillard, Shaun D. Berry

Publikováno v: Immunogenetics. 52(3-4)

The allelic frequencies of TaqI, PstI, and variable number of tandem repeat (VNTR) polymorphisms of the IL-1beta, IL-1 receptor (IL-1Re), and IL-1 receptor antagonist (IL-1Ra) respectively, were investigated in black and white patients with inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff53499ac8a74d70b10e95596b524eec
https://pubmed.ncbi.nlm.nih.gov/11220627

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