Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mark B. van der Hoek"'
Autor:
Chuan Kok Lim, Ornella Romeo, Andrew P Chilver, Bang Manh Tran, Dustin J Flanagan, Emily N Kirby, James Breen, Elizabeth Vincan, Nadia Warner, Erin M McCartney, Mark B Van Der Hoek, Andrew Ruszkiewicz, Edmund Tse, Michael R Beard
Background & AimsCurrent HBVin vitromodel systems suffer from many physiological limitations that restrict understanding of complex viral-host interactions and thus prohibit prediction of diseasein vivo. We developed and assessed adult stem cell (AdS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401a2f7a9b5309afeddbf626642a4a12
https://doi.org/10.1101/2022.10.20.513112
https://doi.org/10.1101/2022.10.20.513112
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141816 (2015)
Streptococcus pneumoniae (the pneumococcus) continues to account for significant morbidity and mortality worldwide, causing life-threatening diseases such as pneumonia, bacteremia and meningitis, as well as less serious infections such as sinusitis,
Externí odkaz:
https://doaj.org/article/15a402363aa546b5b1f9d215949b8114
Autor:
Christopher N. Hahn, Susan L. Heatley, Ilaria S. Pagani, Deborah L. White, Anthony P. Schwarer, David M. Ross, Mark B. Van der Hoek, Chung H. Kok, Timothy P. Hughes, Verity A Saunders
Publikováno v:
The Journal of Molecular Diagnostics. 19:711-721
Somatic mitochondrial DNA (mtDNA) mutations have been identified in many human cancers, including leukemia. To identify somatic mutations, it is necessary to have a control tissue from the same individual for comparison. When patients with leukemia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe66b3a09ac2c149c862f698a69757c
https://doi.org/10.1016/j.jmoldx.2017.05.009
https://doi.org/10.1016/j.jmoldx.2017.05.009
Autor:
Michael Lardelli, Seyyed Hani Moussavi Nik, Esmaeil Ebrahimie, Morgan Newman, Mark B. Van der Hoek
Publikováno v:
Journal of Alzheimer's disease : JAD. 52(2)
Dominant mutations in the PRESENILIN genes PSEN1 and PSEN2 cause familial Alzheimer's disease (fAD) that usually shows onset before 65 years of age. In contrast, genetic variation at the PSEN1 and PSEN2 loci does not appear to contribute to risk for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3e72d430699a0c82d909dea25436d0
https://pubmed.ncbi.nlm.nih.gov/27031468
https://pubmed.ncbi.nlm.nih.gov/27031468
Publikováno v:
Journal of Clinical Investigation. 122:2208-2220
Streptococcus pneumoniae is the most common cause of severe bacterial meningitis in children, the elderly, and compromised individuals. To identify virulence factors preferentially expressed during meningitis, we conducted niche-specific genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c8600697286703320c98a2bf2b2262
https://doi.org/10.1172/jci45850
https://doi.org/10.1172/jci45850
Autor:
Hamish S. Scott, Christopher N. Hahn, Mark B. Van der Hoek, Joseph Carolan, Peter J. Brautigan, Richard J D'Andrea, Chung H. Kok, King Hwa Ling, David J. Torpy, Rosalie Kenyon, Lucia Gagliardi
Publikováno v:
Endocrine-Related Cancer. 19:L19-L23
ACTH-independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of sporadic or familial late-onset Cushing's syndrome. It is a cytologically benign disease, of unknown pathogenesis, and characterised by inefficient steroidogenesis, ascribed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ecc3baf346e979c14bcc16616dadb0
https://doi.org/10.1530/erc-11-0210
https://doi.org/10.1530/erc-11-0210
Publikováno v:
Molecular Carcinogenesis. 52:459-474
Diet-derived butyrate, a histone deacetylase inhibitor (HDI), decreases proliferation and increases apoptosis in colorectal cancer (CRC) cells via epigenetic changes in gene expression. Other HDIs such as suberoylanilide hydroxamic acid (SAHA) and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fb002a34444f6aae19f138ec074e32
https://doi.org/10.1002/mc.21879
https://doi.org/10.1002/mc.21879
Autor:
Julia M. Knelangen, Julie A. Owens, Anne Navarrete Santos, Mark B. van der Hoek, Bernd Fischer, Wee-Ching Kong
Publikováno v:
Physiological Genomics. 43:611-620
Pluripotent embryonic stem cells (ESC) have the potential to differentiate into any cell type of the three germ layers. Differentiation processes depend on genetic and epigenetic factors. The guidance of cell fate determination by microRNAs (miRs) se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c061c9c46cfe700469a12790cfaacde4
https://doi.org/10.1152/physiolgenomics.00116.2010
https://doi.org/10.1152/physiolgenomics.00116.2010
Autor:
Anna Tsykin, Douglas J. Coster, Helen M. Brereton, Keryn A. Williams, Rhys Fogarty, Mark B. Van der Hoek, Michael Michael, Melinda N. Tea
Publikováno v:
Journal of Ocular Biology, Diseases, and Informatics
Different inbred strains of rat differ in their susceptibility to oxygen-induced retinopathy (OIR), an animal model of human retinopathy of prematurity. We examined gene expression in Sprague-Dawley (susceptible) and Fischer 344 (resistant) neonatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4910f2aecc2954fbe0311acd15b25019
https://doi.org/10.1007/s12177-009-9041-7
https://doi.org/10.1007/s12177-009-9041-7
Autor:
Louise Hull, Prabhath Wagaarachchi, Kylie H. Van der Hoek, Sarah A. Robertson, Naomi Perry, E. Maria C. Ohlsson Teague, Mark B. Van der Hoek, Cristin G. Print
Publikováno v:
Molecular Endocrinology. 23:265-275
Endometriosis is a prevalent gynecological disease characterized by growth of endometriotic tissue outside the uterine cavity. MicroRNAs (miRNAs) are naturally occurring posttranscriptional regulatory molecules that potentially play a role in endomet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b0bdedb2a4116c603d94f1f0ba33db
https://doi.org/10.1210/me.2008-0387
https://doi.org/10.1210/me.2008-0387