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pro vyhledávání: '"Mark B. Zimmerman"'
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 9:473-476
Although ACE inhibitors have proven clinically effective as antihypertensive agents, the mechanisms by which they lower blood pressure are not clearly understood. While inhibition of circulating enzyme has been thought to be of primary importance, re
Publikováno v:
Journal of Comparative and Physiological Psychology. 92:501-510
Intravenous infusion of the natriuretic drug furosemide in sheep led to the excretion of large quantitites of hypotonic urine. The sheep consumed more water than was needed simply to restore osmotic equilibrium. The stimulus for the additional intake
Autor:
Patricio Silva, Barry M. Brenner, Helen M. Lafferty, Mark B. Zimmerman, Sharon Anderson, M. E. Gunning
Publikováno v:
Circulation Research. 65:640-646
To investigate the in vivo effects of inhibition of endopeptidase 24.11, an enkephalinase enzyme shown to be involved in atrial natriuretic peptide (ANP) breakdown in vitro, we infused phosphoramidon, a specific inhibitor of endopeptidase 24.11, into
Publikováno v:
Physiology & Behavior. 23:605-607
Rats infused intravenously with homologous renin (0.1–16 U) for 40 min exhibited a linear relation between administered dose and water intake. At the lower doses, observed plasma renin activities also were proportional to water consumption but the
Publikováno v:
Clinical and experimental hypertension. Part A, Theory and practice. 9(2-3)
A series of five structurally distinct ACE inhibitors were evaluated for their ability to inhibit tissue ACE activity in the SHR after oral administration. In the first series of experiments, the ACE inhibitors captopril, enalapril, pentopril, CGS 14
Publikováno v:
ChemInform. 18
A four-step synthesis of 2-chlorodopamine (2b) is presented as well as methods for the syntheses of the N-methyl, ethyl, and n-propyl analogues (2c-e). Compounds 2b and 2c were essentially equipotent to dopamine for increasing renal blood flow in ane
Publikováno v:
Science (New York, N.Y.). 211(4481)
Sheep increased their water intake in proportion to the amount of protein-free, isosmotic fluid that was removed from their blood by ultrafiltration. This behavioral response to hypovolemia was eliminated by crushing the left atrial appendage of the
Publikováno v:
Journal of medicinal chemistry. 29(9)
A four-step synthesis of 2-chlorodopamine (2b) is presented as well as methods for the syntheses of the N-methyl, ethyl, and n-propyl analogues (2c-e). Compounds 2b and 2c were essentially equipotent to dopamine for increasing renal blood flow in ane
Autor:
Edward H. Blaine, Mark B. Zimmerman
Publisher Summary In an experiment described in the chapter, in four conscious water-loaded sheep, angiotensin II (AII) was infused into both carotid arteries at levels that produced low physiological A-II in the cerebral blood supply. The infusion r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1cd95458b70c04cd6477a2187011781
https://doi.org/10.1016/b978-0-08-020933-3.50047-7
https://doi.org/10.1016/b978-0-08-020933-3.50047-7