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pro vyhledávání: '"Mark B. Woerner"'
Autor:
Paola Ciceri, Walter G. Smith, Kathleen M. Leahy, Karen Seibert, Peter C. Isakson, Yan Zhang, Alex Shaffer, Mark B. Woerner
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 302:846-852
Prostaglandin E(2) (PGE(2)) is the major prostaglandin produced both centrally and in the periphery in models of acute and chronic inflammation, and its formation in both locations is blocked by cyclooxygenase-2 (COX-2) inhibitors such as celecoxib.