Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark B. McKeough"'
Autor:
Eric M. Mishkin, Mark B. McKeough, Louise Thai, Spotswood L. Spruance, Barbara A. Araneo, Raymond A. Daynes, Aaron S. Abramovitz, Thomas G. Evans
Publikováno v:
Antiviral Research. 28:39-55
To investigate potential immunologic mechanisms of resistance to recurrent herpes simplex labialis, we assayed serum antibody titers and cultured peripheral blood mononuclear cell (PBMC) cytokine production among patients with a history of frequent e
Publikováno v:
Antiviral Research. 25:185-192
The naturally occurring polyphenolic biopolymer SP-303 has in vitro activity against both HSV-1 and HSV-2, including strains that are resistant to acyclovir. Nine AIDS patients with acyclovir-unresponsive mucocutaneous herpes simplex virus infection
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV. 23(3)
Background Treatment of herpes simplex labialis (HSL) has been associated with modest benefits. This difficulty results from the rapid resolution of the disease accomplished by the immune system, which narrows the window of therapeutic opportunity. T
Autor:
Spotswood L. Spruance, Mark B. McKeough, J. C. B. Stewart, J. L. Cox, Donna J. Freeman, Nathaniel H. Rowe, V. J. Brightman, G Wenerstrom
Publikováno v:
Journal of Infectious Diseases. 161:191-197
In a double-blind, randomized, patient-initiated treatment study at five medical centers, 301 immunocompetent patients experiencing a recurrence of herpes labialis were treated with topical 15% idoxuridine (IDU) in dimethyl sulfoxide (DMSO), 80% DMSO
Publikováno v:
Archives of dermatology. 137(9)
There are 3 new topical treatments for herpes labialis that have either been approved by the US Food and Drug Administration (penciclovir cream [Denavir] and n-docosanol cream [Abreva]) or recently undergone extensive clinical evaluation (acyclovir c
Publikováno v:
The Journal of infectious diseases. 181(6)
To investigate the efficacy of corticosteroids for the treatment of herpes labialis, we compared famciclovir (Famvir, 500 mg 33/day po [per os] for 5 days) and topical fluocinonide (0.05% Lidex Gel 33/day for 5 days) with famciclovir and topical vehi
Publisher Summary This chapter presents a guinea pig model of herpes skin infection. The animals used in this model are female Hartley outbred albino guinea pigs, of 500 g each. Each of them are injected with about 0.24 ml of 50 mg ketamine/ml plus 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faca5f411c366c43b6af570b36e4b5a5
https://doi.org/10.1016/b978-012775390-4/50248-7
https://doi.org/10.1016/b978-012775390-4/50248-7
Susceptibility to herpes labialis following multiple experimental exposures to ultraviolet radiation
Publikováno v:
Antiviral research. 28(1)
We studied susceptibility to herpes labialis by exposing 20 volunteers to experimental ultraviolet radiation (UVR) on three occasions at 3- to 4-month intervals. The number of patients who developed lesions after each session was 9 20 (45%), 9 20 (45
Publikováno v:
Journal of clinical microbiology. 32(12)
We examined the oral secretions of 25 patients for herpes simplex virus (HSV) at the time of and following experimental UV radiation (UVR). HSV was detected in one or more oral secretion specimens in 5 of 12 (42%) cases by cell culture and in 8 of 12
Publikováno v:
Annals of the New York Academy of Sciences. 411:28-33
To evaluate the importance of drug delivery experimentally, we have measured the penetration of acyclovir (ACV) through guinea pig skin in vitro from different drug vehicles and compared these findings with the efficacy of two topical formulations of