Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Mark B. Cannell"'
Publikováno v:
Cells, Vol 13, Iss 17, p 1455 (2024)
The atrioventricular node (AVN) is a key component of the cardiac conduction system and takes over pacemaking of the ventricles if the sinoatrial node fails. IP3 (inositol 1,4,5 trisphosphate) can modulate excitability of myocytes from other regions
Externí odkaz:
https://doaj.org/article/4a47348269214342815b39f379da96ab
Publikováno v:
PLoS ONE, Vol 6, Iss 4 (2011)
Externí odkaz:
https://doaj.org/article/232fb02bcb6340a3b99398230619d8c5
Autor:
Ewan D. Fowler, Nan Wang, Melanie J. Hezzell, Guillaume Chanoit, Jules C. Hancox, Mark B. Cannell
Publikováno v:
Fowler, E D, Wang, N, Hezzell, M J, Chanoit, G P A, Hancox, J C & Cannell, M B 2022, ' Improved Ca2+ release synchrony following selective modification of Itof and phase 1 repolarization in normal and failing ventricular myocytes ', Journal of Molecular and Cellular Cardiology, vol. 172, pp. 52-62 . https://doi.org/10.1016/j.yjmcc.2022.07.009
Loss of ventricular action potential (AP) early phase 1 repolarization may contribute to the impaired Ca 2+ release and increased risk of sudden cardiac death in heart failure. Therefore, restoring AP phase 1 by augmenting the fast transient outward
Autor:
Eva A. Rog-Zielinska, Robin Moss, Gunnar Seemann, W. Kaltenbacher, Peter Kohl, Joachim Greiner, Mark B. Cannell, Paul Verkade
Publikováno v:
et al. 2020, ' Nano-scale morphology of cardiomyocyte t-tubule/sarcoplasmic reticulum junctions revealed by ultra-rapid high-pressure freezing and electron tomography ', Journal of Molecular and Cellular Cardiology, vol. 153, pp. 86-92 . https://doi.org/10.1016/j.yjmcc.2020.12.006
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology
Detailed knowledge of the ultrastructure of intracellular compartments is a prerequisite for our understanding of how cells function. In cardiac muscle cells, close apposition of transverse (t)-tubule (TT) and sarcoplasmic reticulum (SR) membranes su
Autor:
Ewan D, Fowler, Nan, Wang, Melanie J, Hezzell, Guillaume, Chanoit, Jules C, Hancox, Mark B, Cannell
Publikováno v:
Journal of molecular and cellular cardiology. 172
Loss of ventricular action potential (AP) early phase 1 repolarization may contribute to the impaired Ca
Publikováno v:
Wang, N, Dries, E, Fowler, E D, Harmer, S C, Hancox, J C & Cannell, M B 2021, ' Inducing Ito,f and phase 1 repolarization of the cardiac action potential with a Kv4.3/KChIP2.1 bicistronic transgene ', Journal of Molecular and Cellular Cardiology, vol. 164, pp. 29-41 . https://doi.org/10.1016/j.yjmcc.2021.11.004
The fast transient outward potassium current (Ito,f) plays a key role in phase 1 repolarization of the human cardiac action potential (AP) and its reduction in heart failure (HF) contributes to the loss of contractility. Therefore, restoring Ito,f mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5ca7ed2fb95d73d98b22469c4bae5e
https://research-information.bris.ac.uk/ws/files/304888323/1_s2.0_S0022282821002194_main_2.pdf
https://research-information.bris.ac.uk/ws/files/304888323/1_s2.0_S0022282821002194_main_2.pdf
Autor:
Yue-Kun eJu, Bon Hyang Lee, Sofie eTrajanovska, Guoliang eHao, David G Allen, Ming eLei, Mark B Cannell
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Atrial fibrillation (AF) is a significant contributor to cardiovascular morbidity and mortality. The currently available treatments are limited and AF continues to be a major clinical challenge. Clinical studies have shown that AF is frequently assoc
Externí odkaz:
https://doaj.org/article/aee9e542c28e47b8ad21788aad7bc129
Autor:
Haifei Zhang, Mark B Cannell, Shang Jin Kim, Judy J Watson, Ruth Norman, Sarah C Calaghan, Clive H Orchard, Andrew F James
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144309 (2015)
Atrial remodeling due to elevated arterial pressure predisposes the heart to atrial fibrillation (AF). Although abnormal sarcoplasmic reticulum (SR) function has been associated with AF, there is little information on the effects of elevated afterloa
Externí odkaz:
https://doaj.org/article/25c6851491914da6a8505d06140b58e6
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17901 (2011)
BACKGROUND: The cardiac myocyte t-tubular system ensures rapid, uniform cell activation and several experimental lines of evidence suggest changes in the t-tubular system and associated excitation-contraction coupling proteins may occur in heart fail
Externí odkaz:
https://doaj.org/article/7f10de691cc84511bfbec4125b9b53be
Autor:
Mark B. Cannell, Guy Cox
Publikováno v:
Fundamentals of Fluorescence Imaging ISBN: 9781351129404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f17de522bcdbf7090dd7d19e20da3d3b
https://doi.org/10.1201/9781351129404-4
https://doi.org/10.1201/9781351129404-4