Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Mark B. Mitchell"'
Autor:
Tyler G. Grissom, Anatoly I. Frenkel, Craig L. Hill, Sanjit Ghose, Djamaladdin G. Musaev, Mark B. Mitchell, Alex Balboa, John R. Morris, Yiyao Tian, Wesley O. Gordon, Daniel L. Collins-Wildman, Anna M. Plonka, Amani M. Ebrahim
Publikováno v:
Chemistry of Materials. 31:9904-9914
Developing novel and more efficient filters for chemical warfare agent (CWA) decomposition remains an important challenge for modern technology due to the continuous threat those weapons present in...
Autor:
Wesley O. Gordon, Djamaladdin G. Musaev, John R. Morris, Mark B. Mitchell, Anatoly I. Frenkel, Craig L. Hill, Alexey L. Kaledin, Alex Balboa, Christopher J. Karwacki, Diego Troya
Publikováno v:
Chemical Physics. 518:30-37
We report computational studies of (O,O-dimethyl)-(O-4-nitrophenyl)-phosphate (DMNP) and (O,O-dimethyl)-(O-phenyl)-phosphate (DMPP) decomposition by the Zr-substituted Polyoxometalate {α-PW11O39Zr(μ-OH)(H2O)}4−, which has been recently shown to b
Autor:
Mark B. Mitchell, Djamaladdin G. Musaev, Daniel L. Collins-Wildman, Alexey L. Kaledin, Yiyao Tian, Harrison J Siegal, John R. Morris, Wesley O. Gordon, Tyler G. Grissom, Christopher J. Karwacki, Diego Troya, Anatoly I. Frenkel, Craig L. Hill, Anna M. Plonka, Amani M. Ebrahim, Conor H. Sharp
Publikováno v:
ACS applied materialsinterfaces. 12(13)
The threat of chemical warfare agents (CWAs), assured by their ease of synthesis and effectiveness as a terrorizing weapon, will persist long after the once-tremendous stockpiles in the U.S. and elsewhere are finally destroyed. As such, soldier and c
Autor:
Matthew Jude Sharp, Will L. Canoy, Kae M. Bullock, Eric Eugene Boros, Xiao-ming M. Zhou, Richard T. Matsuoka, Greg A. Erickson, Vassil I. Elitzin, Mark B. Mitchell, Matthew C. Salmon, David H. Igo, Nicole M. Deschamps, Daniel W. Reynolds, Andrew D. Brown, Gregory E. Peckham, Istvan Kaldor, Jennifer F. Toczko, Shannon Condon, Carpenter Andrew J, Elie Amine Tabet, Jing M. Fang, Biren K. Joshi, Lianming Michael Wu, Jeremy D. Cobb
Publikováno v:
Organic Process Research & Development. 20:1469-1475
Practical and scalable syntheses were developed that were used to prepare multikilogram batches of GSK1292263A (1) and GSK2041706A (15), two potent G protein-coupled receptor 119 (GPR119) agonists. Both syntheses employed relatively cheap and readily
Autor:
Mark B. Mitchell, Dale M. Daniel
Publikováno v:
The American Surgeon. 80:1069-1073
The discharge of the patients directly from the recovery room after appendectomy has only recently been described in the literature. Because the 30-day readmission rate is used as a surrogate for safety and as a means to identify complications from a
Autor:
Jiasheng Guo, Marie-Catherine Salaun, Greg A. Erickson, Andrew J. Whitehead, Mark B. Mitchell, Mike McClure
Publikováno v:
Tetrahedron Letters. 55:6007-6010
A new synthesis of Lapatinib, an orally active drug for breast cancer, is described. The synthesis involves a palladium catalyzed regioselective arylation of furfural with 6-bromo- N -(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine. This k
Autor:
Alan Millar, Claire Crawford, Sandeep B. Kedia, Bobby N. Glover, Jeremiah D. Powers, Christopher J. Nichols, Malcolm B. Berry, Mark B. Mitchell, Michael S. McClure, Brian C. Crump, Daniel E. Patterson, Darren Caine
Publikováno v:
European Journal of Organic Chemistry. 2012:3561-3565
A highly selective method for the alkoxycarboxylation and acylation of primary alcohols of pyranose derivatives is described. The reaction is high yielding and proceeds under mild conditions with 0.15–1 mol-% Sc(OTf)3 used in combination with anhyd
Publikováno v:
The Journal of Physical Chemistry C. 115:11514-11524
Dimethyl methylphosphonate (DMMP) is a widely used simulant for chemical warfare agents and pesticides. This work examined the room temperature reaction of DMMP with ozone on alumina-supported manganese oxide. The reaction on the MnOx/Al2O3 surface s
Autor:
Bing Liu, Elie A. Tabet, Mark B. Mitchell, Vassil I. Elitzin, Nicole Marie Deschamps, Matthew J. Sharp
Publikováno v:
The Journal of Organic Chemistry. 76:712-715
The triple reuptake inhibitor GSK1360707F was synthesized via an efficient and scalable route that features an enyne cycloisomerization reaction catalyzed by either Pt(II) or Au(I). Key aspects of this work such as the choice of the nitrogen protecti
Publikováno v:
Organic Process Research & Development. 14:712-715
Parallel microreactor screening enabled rapid identification of effective conditions for PTC-mediated Knoevenagel condensation between aldehyde (1) and thiazalone (2), affording a dramatic reduction in cycle time when compared to traditional conditio