Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Mark B NOTTLE"'
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 6, Pp 411-417 (2024)
Oocyte developmental competence declines in women aged 35 and older resulting in many women resorting to IVF. The present study determined whether adding Granulocyte-macrophage colony-stimulating factor (GM-CSF) during in vitro oocyte maturation (IVM
Externí odkaz:
https://doaj.org/article/aa29bd1e34144d9ca3986f3ce9002c51
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 3, Pp 1-8 (2024)
The present study determined whether adding granulocyte–macrophage colony-stimulating factor (GM-CSF) during in vitro oocyte maturation (IVM) could improve oocyte developmental competence by examining embryo development and implantation and birth r
Externí odkaz:
https://doaj.org/article/086a317d8f4c4e8c97a5d1fa8aa5c437
Autor:
Wayne J. Hawthorne, Evelyn J. Salvaris, Yi Vee Chew, Heather Burns, Joanne Hawkes, Helen Barlow, Min Hu, Andrew M. Lew, Mark B. Nottle, Philip J. O’Connell, Peter J. Cowan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Xenotransplantation using porcine donors is rapidly approaching clinical applicability as an alternative therapy for treatment of many end-stage diseases including type 1 diabetes. Porcine neonatal islet cell clusters (NICC) have normalised blood sug
Externí odkaz:
https://doaj.org/article/8c52f60777f04c9ab509a31950cc5a1a
Autor:
Mark B. Nottle, Evelyn J. Salvaris, Nella Fisicaro, Stephen McIlfatrick, Ivan Vassiliev, Wayne J. Hawthorne, Philip J. O’Connell, Jamie L. Brady, Andrew M. Lew, Peter J. Cowan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Xenotransplantation from pigs has been advocated as a solution to the perennial shortage of donated human organs and tissues. CRISPR/Cas9 has facilitated the silencing of genes in donor pigs that contribute to xenograft rejection. However, t
Externí odkaz:
https://doaj.org/article/13fe765c6d834f9facf6f7bbc3879a6c
Publikováno v:
XenotransplantationREFERENCES.
A number of reviews have been written recently celebrating the 25th anniversary of the birth of Dolly the cloned sheep and the effect this breakthrough has had on various fields of research. However, arguably the biggest impact Dolly has had is on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e7197dfff80f751f7aacbd7eeb26db
https://pubmed.ncbi.nlm.nih.gov/36413478
https://pubmed.ncbi.nlm.nih.gov/36413478
Autor:
Wayne J Hawthorne, Evelyn Salvaris, Min Hu, Andrew Lew, Mark B Nottle, Philip J O’Connell, Peter J Cowan
Publikováno v:
Transplantation. 106:S286-S286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f541c6bc6c0fd0dae0a16ac5bbdc0f8
https://doi.org/10.1097/01.tp.0000886908.10903.0b
https://doi.org/10.1097/01.tp.0000886908.10903.0b
Autor:
Andrew M. Lew, Nella Fisicaro, Wayne J. Hawthorne, Peter J. Cowan, Mark B. Nottle, Jamie L. Brady, Evelyn J Salvaris, Ivan Vassiliev, Stephen M. McIlfatrick, Philip J. O'Connell
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
Xenotransplantation from pigs has been advocated as a solution to the perennial shortage of donated human organs and tissues. CRISPR/Cas9 has facilitated the silencing of genes in donor pigs that contribute to xenograft rejection. However, the genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8968a79880f2ed22568c7bcc3defdd
https://doaj.org/article/13fe765c6d834f9facf6f7bbc3879a6c
https://doaj.org/article/13fe765c6d834f9facf6f7bbc3879a6c
Autor:
Mark B. Nottle, Evelyn J Salvaris, Matthew Wakefield, Wayne J. Hawthorne, Peter J. Cowan, Nella Fisicaro, Gayle K Philip
Publikováno v:
Xenotransplantation. 27
Gene editing using clustered regularly interspaced short palindromic repeats/Cas9 has great potential for improving the compatibility of porcine organs with human recipients. However, the risk of detrimental off-target mutations in gene-edited pigs r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f29701abb5b2dd201b5ac70435ec2d
https://doi.org/10.1111/xen.12551
https://doi.org/10.1111/xen.12551
Publikováno v:
Theriogenology. 86:1008-1013
The present study was undertaken to examine the effect of feed restriction on ovulation rate and in vivo blastocyst development in gilts and sows. In the first experiment, gilts were feed restricted (1 vs. 2.5 times maintenance requirement) during th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5a58c6a02bc832a6fe7621bfd97bf4
https://doi.org/10.1016/j.theriogenology.2016.03.029
https://doi.org/10.1016/j.theriogenology.2016.03.029
Publikováno v:
Current opinion in organ transplantation. 24(1)
The use of genetically modified donor pigs has been integral to recent major advances in xenograft survival in preclinical nonhuman primate models. CRISPR-Cas9 gene editing technology has dramatically accelerated the development of multimodified pigs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cda34ccc5301b0e5e13fa2f23fd367
https://pubmed.ncbi.nlm.nih.gov/30480643
https://pubmed.ncbi.nlm.nih.gov/30480643