Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mark B Headley"'
Autor:
Meghan A Morrissey, Adam P Williamson, Adriana M Steinbach, Edward W Roberts, Nadja Kern, Mark B Headley, Ronald D Vale
Publikováno v:
eLife, Vol 7 (2018)
Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T cells to kill cancer. The success of CAR-T cell therapies highlights the promise of programmed immunity and suggests that applying CAR strategies to other immune cell lineages
Externí odkaz:
https://doaj.org/article/b6c213511ca34e6e95a2eeaeb0ed0238
Autor:
Kelly Kersten, Ran You, Sophia Liang, Kevin M. Tharp, Joshua Pollack, Valerie M. Weaver, Matthew F. Krummel, Mark B. Headley
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112582- (2023)
Summary: Pre-metastatic niche formation is a critical step during the metastatic spread of cancer. One way by which primary tumors prime host cells at future metastatic sites is through the shedding of tumor-derived microparticles as a consequence of
Externí odkaz:
https://doaj.org/article/93fdfb19941240b39f468bae24071767
Autor:
Andrew Zloza, A. Karolina Palucka, Lisa M. Coussens, Philip J. Gotwals, Mark B. Headley, Elizabeth M. Jaffee, Amanda W. Lund, Arlene H. Sharpe, Mario Sznol, Derek A. Wainwright, Kwok-Kin Wong, Marcus W. Bosenberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-9 (2017)
Abstract Understanding how murine models can elucidate the mechanisms underlying antitumor immune responses and advance immune-based drug development is essential to advancing the field of cancer immunotherapy. The Society for Immunotherapy of Cancer
Externí odkaz:
https://doaj.org/article/f66e6ac47cdc431ebab99578560db508
Autor:
Raphael Gottardo, Charles-Antoine Dutertre, Evan W. Newell, Florent Ginhoux, Mark B. Headley, Daniel J. Campbell, Daniel Tolstrup, Etienne Becht, Peter A. Morawski
Publikováno v:
Science Advances
Description
This study presents a novel method for low-cost cell surface proteomics using flow cytometry and machine learning.
Modern immunologic research increasingly requires high-dimensional analyses to understand the complex milieu of c
This study presents a novel method for low-cost cell surface proteomics using flow cytometry and machine learning.
Modern immunologic research increasingly requires high-dimensional analyses to understand the complex milieu of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1a78b2d1fb97e69557ecb0aee93e3f
https://doi.org/10.1126/sciadv.abg0505
https://doi.org/10.1126/sciadv.abg0505
Autor:
Mark B. Headley, Matthew F. Krummel, Megan K. Ruhland, Tanya S. Freedman, Carlos A. Castellanos, Alexis J. Combes, Nina K. Serwas
Publikováno v:
The Journal of experimental medicine, vol 217, iss 9
Journal of Experimental Medicine
The Journal of Experimental Medicine
Journal of Experimental Medicine
The Journal of Experimental Medicine
Matthew Krummel and colleagues discuss the positive trends and initiatives that emerged among scientists during the COVID-19 lockdown.
The response to the COVID-19 crisis across most research institutions mandated ceasing nonessential research a
The response to the COVID-19 crisis across most research institutions mandated ceasing nonessential research a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c534bd3ae260855f021125a8e7ed728b
https://doi.org/10.1084/jem.20201276
https://doi.org/10.1084/jem.20201276
Autor:
Rosemary J. Akhurst, Bahar Zivak, Eswari Dodagatta-Marri, John T. Li, Niessen Kyle Steven, Bing Yang, Szu-Ying Chen, Joselyn S. Del Cid, Dean Sheppard, Michael Rosenblum, Benjia Liang, Dominique S. Meyer, Tatsuya Tsukui, Anand Giddabasappa, Hsiao-Yen Ma, Lauren Pinzas, Sharon Yang, Mark B. Headley, Kai-Hui Sun, Nilgun Isik Reed, Xin Ren, Joseph Dal Porto, Kavon Noorbehesht, Amha Atakilit, Byron Hann
Publikováno v:
Cell reports
SUMMARY αvβ8 integrin, a key activator of transforming growth factor β (TGF-β), inhibits anti-tumor immunity. We show that a potent blocking monoclonal antibody against αvβ8 (ADWA-11) causes growth suppression or complete regression in syngenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4c1017e7cdae52d716d3d8881ffa8c
https://pubmed.ncbi.nlm.nih.gov/34233193
https://pubmed.ncbi.nlm.nih.gov/34233193
Autor:
Maeva Adoumie, Joselyn S. Del Cid, Dean Sheppard, Tatsuya Tsukui, Lauren Pinzas, Eswari Dodagatta-Marri, Xin Ren, John T. Li, Sharon Yang, Niessen Kyle Steven, Bing Yang, Anand Giddabasappa, Mark B. Headley, Benjia Liang, Kai-Hui Sun, Nilgun Isik Reed, Hsiao-Yen Ma, Bahar Zivak, Dominique S. Meyer, Rosemary J. Akhurst, Michael Rosenblum, Amha Atakilit, Kavon Noorbehesht, Byron Hann, Joseph Dal Porto
The αvβ8 integrin is a key activator of transforming growth factor β (TGF β), which has been shown to inhibit anti-tumor immunity. Previous work has suggested that αvβ8 on tumor cells could modulate tumor growth and responses to immune checkpoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff1856d50cc8a87bd543566bac9f47b
https://doi.org/10.1101/2020.05.14.084913
https://doi.org/10.1101/2020.05.14.084913
Autor:
Bahar Zivak, Dominique S. Meyer, John T. Li, Rosemary J. Akhurst, Nilgun Isik Reed, Eswari Dodagatta-Marri, Mark B. Headley, Anand Giddabasappa, Kai-Hui Sun, Niessen Kyle Steven, Bing Yang, Sharon Yang, Joselyn S. Del Cid, Dean Sheppard, Maeva Adoumie, Michael Rosenblum, Tatsuya Tsukui, Hsiao-Yen Ma, Amha Atakilit, Xin Ren, Kavon Noorbehesht, Joseph Dal Porto, Byron Hann, Benjia Liang, Lauren Pinzas
Publikováno v:
SSRN Electronic Journal.
The αvβ8 integrin is a key activator of transforming growth factor β(TGFβ), which has been shown to inhibit anti-tumor immunity. Previous work has suggested that αvβ8 on tumor cells could modulate tumor growth and responses to immune checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52463993181185ad72799126a230c36b
https://doi.org/10.2139/ssrn.3588885
https://doi.org/10.2139/ssrn.3588885
Autor:
Daniel Tolstrup, Etienne Becht, Charles-Antoine Dutertre, Raphael Gottardo, Florent Ginhoux, Mark B. Headley, Evan W. Newell
Publikováno v:
SSRN Electronic Journal.
Modern immunologic research increasingly requires high-dimensional analyses in order to understand the complex milieu of cell-types that comprise the tissue microenvironments of disease. To achieve this, we developed Infinity Flow combining hundreds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0903047e05ee4ccdd22e55475874701d
https://doi.org/10.2139/ssrn.3656603
https://doi.org/10.2139/ssrn.3656603
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
Autor:
Chih Yang Wang, Charlotte D. Koopman, Jonathan Chou, Niwen Kong, Mark B. Headley, Carrie Maynard, Charlene Lin, Zena Werb, Renske J.E. van den Bijgaart, Dalit Talmi-Frank, Irit Sagi, Vicki Plaks, Mark Owyong, Inna Solomonov, Gizem Efe, Elin Synnøve Hadler-Olsen
Publikováno v:
Life science alliance, vol 2, iss 6
Life Science Alliance, 2
Life Science Alliance
Life Science Alliance, 2, 6
Life Science Alliance, 2
Life Science Alliance
Life Science Alliance, 2, 6
Inhibition of active MMP9 early during tumorigenesis suppresses tumor cell migration, invasion, and colony formation and tilts the balance towards anti-tumor immunity by activating CD8+ T cells.
Metastasis, the main cause of cancer-related death
Metastasis, the main cause of cancer-related death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f19a56d83f85c84a28ad246454f4f13
https://escholarship.org/uc/item/3339f30k
https://escholarship.org/uc/item/3339f30k