Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mark B Ericksen"'
Autor:
Lisa J Martin, Jayanta Gupta, Soma S S K Jyothula, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Tia L Patterson, Mark B Ericksen, Hua He, Aaron M Gibson, Tesfaye M Baye, Sushil Amirisetty, Anna M Tsoras, Youbao Sha, N Tony Eissa, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33454 (2012)
Rationale and objectiveAutophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders, and response to vira
Externí odkaz:
https://doaj.org/article/387c3faf46704aaca8344c0be9ea39da
Autor:
Tesfaye M Baye, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Lisa J Martin, Mark Lindsey, Tia L Patterson, Hua He, Mark B Ericksen, Jayanta Gupta, Anna M Tsoras, Andrew Lindsley, Marc E Rothenberg, Marsha Wills-Karp, N Tony Eissa, Larry Borish, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16522 (2011)
BackgroundCandidate gene case-control studies have identified several single nucleotide polymorphisms (SNPs) that are associated with asthma susceptibility. Most of these studies have been restricted to evaluations of specific SNPs within a single ge
Externí odkaz:
https://doaj.org/article/ccb79b07379a45bcbabd5246bbd0edd7
Autor:
Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Ning Wang, Lisa J Martin, Mark Lindsey, Mark B Ericksen, Hua He, Tia L Patterson, Tesfaye M Baye, Dara Torgerson, Lindsey A Roth, Jayanta Gupta, Umasundari Sivaprasad, Aaron M Gibson, Anna M Tsoras, Donglei Hu, Celeste Eng, Rocío Chapela, José R Rodríguez-Santana, William Rodríguez-Cintrón, Pedro C Avila, Kenneth Beckman, Max A Seibold, Chris Gignoux, Salma M Musaad, Weiguo Chen, Esteban González Burchard, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23714 (2011)
Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes.Using epithelial RNA expression arrays, HapMap allele fr
Externí odkaz:
https://doaj.org/article/5f4cc418e1864f3d8f3a32d8a027af35
Autor:
Mark B. Ericksen, Premkumar Vummidi Giridhar, Anusha Sridharan, Gurjit K. Khurana Hershey, Priya Rajavelu, Joseph A. Kitzmiller, Sheila M. Bell, Anjaparavanda P. Naren, Jeffrey A. Whitsett, Eric B. Brandt, Cheng-Lun Na, Matthew Kofron, Changsuk Moon
Publikováno v:
The Journal of Immunology. 197:4228-4239
KIF3A, the gene encoding kinesin family member 3A, is a susceptibility gene locus associated with asthma; however, mechanisms by which KIF3A might influence the pathogenesis of the disorder are unknown. In this study, we deleted the mouse Kif3a gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546ad70955696022db31e895278d9bb5
https://doi.org/10.4049/jimmunol.1600926
https://doi.org/10.4049/jimmunol.1600926
Autor:
Ashley Ulm, Hari K. Somineni, Christopher N. Mayhew, James M. Wells, Hong Ji, Gurjit K. Khurana Hershey, Xue Zhang, Mark B. Ericksen, Sunghee Oh
Publikováno v:
The Journal of allergy and clinical immunology, vol 135, iss 1
Background Induced pluripotent stem cells (iPSCs) hold tremendous potential, both as a biological tool to uncover the pathophysiology of disease by creating relevant human cell models and as a source of cells for cell-based therapeutic applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdfe6812c4fea821594f8f6eae31960
https://doi.org/10.1016/j.jaci.2014.08.038
https://doi.org/10.1016/j.jaci.2014.08.038
Autor:
James E. Lockey, Joey Gareri, G.K. Khurana Hershey, Gideon Koren, Umasundari Sivaprasad, J. M. Biagini Myers, Mark B. Ericksen, David I. Bernstein, Jeff Burkle, Valentina Pilipenko, Mark Lindsey, Lisa J. Martin, Angelika Lubetsky, Grace K. LeMasters
Publikováno v:
The pharmacogenomics journal
Cotinine is a proxy for secondhand smoke (SHS) exposure. Genetic variation along nicotine and cotinine metabolic pathways may alter the internal cotinine dose, leading to misinterpretations of exposure-health outcome associations. Caucasian children
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15d8a85e100f0a6ad6316d9486d2726
http://europepmc.org/articles/PMC4342329
http://europepmc.org/articles/PMC4342329
Publikováno v:
Journal of Allergy and Clinical Immunology. 114:553-560
Background IL-13 is a key mediator of allergic asthma. IL-13 mediates its effects via its receptor, a heterodimer composed of IL-4Rα and IL-13Rα1. Polymorphic variants of both IL-13 and IL-4Rα have been shown to be associated with atopy. Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f877aed194f6d546fc27bdd35e607413
https://doi.org/10.1016/j.jaci.2004.04.044
https://doi.org/10.1016/j.jaci.2004.04.044
Autor:
Gurjit K. Khurana Hershey, Michael O. Daines, Christie M. Cunningham, Mark B. Ericksen, Ryan P. Andrews
Publikováno v:
Journal of Biological Chemistry. 277:36563-36569
Signal transducer and activator of transcription (Stat)6 is a transcription factor important for the development of Th2 cells and regulation of gene expression by IL-4 and IL-13. It is known that Stat6 is rapidly activated in response to IL-4; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99e165d07ecb411c79b57362dedeea5
https://doi.org/10.1074/jbc.m200986200
https://doi.org/10.1074/jbc.m200986200
Autor:
Christie M. Cunningham, Ranajit Chakraborty, Gurjit K. Khurana Hershey, Mark B. Ericksen, Ryan P. Andrews, Jonathan A. Bernstein, Ning Wang, Kimberly A. Risma
Publikováno v:
The Journal of Immunology. 169:1604-1610
Asthma is a complex polygenic disease. Many studies have implicated the importance of IL-4Rα in the development of allergic inflammation and its gene has been implicated in the genetics of asthma and atopy. In this study, we examined the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791674b8928e32fd8a9e0c29d815dfea
https://doi.org/10.4049/jimmunol.169.3.1604
https://doi.org/10.4049/jimmunol.169.3.1604
Autor:
Michael Zeisberg, Raghu Kalluri, Fuad N. Ziyadeh, Yuki Hamano, Mark B. Ericksen, Eric G. Neilson
Publikováno v:
Biochemical and Biophysical Research Communications. 295:401-407
Type IV collagen, which is encoded by six genetically distinct alpha-chains (alpha 1-alpha 6), is a major component of the kidney glomerulus. The alpha 1(IV) and alpha 2(IV) chains are present predominantly in the mesangial matrix, whereas the alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cae52228a4cb74ed8ce6b06ef4674f
https://doi.org/10.1016/s0006-291x(02)00693-9
https://doi.org/10.1016/s0006-291x(02)00693-9