Double Duty: Complete Pathologic Response of Two Colonic Primaries with Mosaicism of a Novel MLH1 Mutation to Neoadjuvant Pembrolizumab

Autor: Beatrice Preti, Laila Schenkel, Matthew Cecchini, Tommaso Romagnoli, Michael Susmoy Sanatani, Karissa French, Patrick Colquhoun, Mark David Vincent

Publikováno v: Current Oncology, Vol 30, Iss 10, Pp 9039-9048 (2023)

We present a fascinating case of a 57-year-old male with a novel mutation in MLH1 (MLH1:c.1288G > T, p.(Glu430*)), who presented with two synchronous colonic tumours, initially deemed unresectable, and experienced a complete pathological response on

Externí odkaz: https://doaj.org/article/7222e6c01cc74e3fb4426add00812da2

The restoration of the beautiful soul construct in the lives and works of six visual artists: Wassily Kandinsky, Käthe Kollwitz, Jacob Lawrence, Mark Rothko, Vincent van Gogh, and Remedios Varo

Autor: Masi, Robin

The Nobel Prize, arguably the most prestigious acknowledgement of ethical achievement, was established by Alfred Nobel to honor those who have performed “to the greatest benefit of mankind” (Nobel, 2018). Despite the many categories for which Nob

Externí odkaz: https://hdl.handle.net/2144/30708

The quality of life in neoadjuvant versus adjuvant therapy of esophageal cancer treatment trial (QUINTETT): Randomized parallel clinical superiority trial

Autor: Richard A. Malthaner, Edward Yu, Michael Sanatani, Debra Lewis, Andrew Warner, A. Rashid Dar, Brian P. Yaremko, Joel Bierer, David A. Palma, Dalilah Fortin, Richard I. Inculet, Eric Fréchette, Jacques Raphael, Stewart Gaede, Sara Kuruvilla, Jawaid Younus, Mark D. Vincent, George B. Rodrigues

Publikováno v: Thoracic Cancer, Vol 13, Iss 13, Pp 1898-1915 (2022)

Abstract Background We compared the health‐related quality of life (HRQOL) in patients undergoing trimodality therapy for resectable stage I‐III esophageal cancer. Methods A total of 96 patients were randomized to standard neoadjuvant cisplatin a

Externí odkaz: https://doaj.org/article/3b12890c920c426ab850df2b1fe0356a

Skin Deep: A Fascinating Case Report of Immunotherapy-Triggered, Treatment-Refractory Autoimmune Lichen Planus and Keratoacanthoma

Autor: Beatrice T. B. Preti, Alec Pencz, Jeffery J. M. Cowger, Mark D. Vincent, Daniel Breadner

Publikováno v: Case Reports in Oncology, Vol 14, Iss 2, Pp 1189-1193 (2021)

This case discusses a 62-year-old woman with de novo metastatic lung adenocarcinoma (PD-L1 >50% with a KRAS G12C mutation, ALK and EGFR negative) who was on pembrolizumab for 1 year without any significant toxicity, only low-grade dermatitis and hypo

Externí odkaz: https://doaj.org/article/b49e0bb04f7a4f9698e99c787f282971

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects

Autor: Athel Cornish-Bowden, David Rasnick, Henry H. Heng, Steven Horne, Batoul Abdallah, Guo Liu, Christine J. Ye, Mathew Bloomfield, Mark D. Vincent, C. Marcelo Aldaz, Jenny Karlsson, Anders Valind, Caroline Jansson, David Gisselsson, Jennifer A. Marshall Graves, Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Nataliya L. Huleyuk, Vladimir P. Baklaushev, Oksana A. Kovaleva, Vladimir P. Chekhonin, Yegor S. Vassetzky, Stanislav S. Avdieiev, Bjorn Bakker, Aaron S. Taudt, Mirjam E. Belderbos, David Porubsky, Diana C. J. Spierings, Tristan V. de Jong, Nancy Halsema, Hinke G. Kazemier, Karina Hoekstra-Wakker, Allan Bradley, Eveline S. J. M. de Bont, Anke van den Berg, Victor Guryev, Peter M. Lansdorp, Maria Colomé Tatché, Floris Foijer, Thomas Liehr, Nicolaas C. Baudoin, Joshua M. Nicholson, Kimberly Soto, Isabel Quintanilla, Jordi Camps, Daniela Cimini, M. Dürrbaum, N. Donnelly, V. Passerini, C. Kruse, B. Habermann, Z. Storchová, Daniele Mandrioli, Fiorella Belpoggi, Ellen K Silbergeld, Melissa J Perry, Rolf I. Skotheim, Marthe Løvf, Bjarne Johannessen, Andreas M. Hoff, Sen Zhao, Jonas M. SveeStrømme, Anita Sveen, Ragnhild A. Lothe, R. Hehlmann, A. Voskanyan, A. Fabarius, Alfred Böcking, Stefan Biesterfeld, Leonid Berynskyy, Christof Börgermann, Rainer Engers, Josef Dietz, A. Fritz, N. Sehgal, J. Vecerova, B. Stojkovicz, H. Ding, N. Page, C. Tye, S. Bhattacharya, J. Xu, G. Stein, J. Stein, R. Berezney, Xue Gong, Sarah Grasedieck, Julian Swoboda, Frank G. Rücker, Lars Bullinger, Jonathan R. Pollack, Fani-Marlen Roumelioti, Maria Chiourea, Christina Raftopoulou, Sarantis Gagos, Peter Duesberg, Mat Bloomfield, Sunyoung Hwang, Hans Tobias Gustafsson, Ciara O’Sullivan, Aracelli Acevedo-Colina, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, Eduardo M. Torres, Martha R. Stampfer, Lukas Vrba, Mark A. LaBarge, Bernard Futscher, James C. Garbe, Yi-Hong Zhou, Andrew L. Trinh, Michelle Digman

Publikováno v: Molecular Cytogenetics, Vol 10, Iss S2, Pp 77-94 (2017)

Externí odkaz: https://doaj.org/article/b6866d4289674f288bf6c946e8f882e4