Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mark A. Tornetta"'
Autor:
D Fink, D Fisher, Raymond W. Sweet, Ping Tsui, D Geng, D Knight, K O'Neil, Mark A. Tornetta, M Brigham-Burke, A Schantz, D Lombardo
Publikováno v:
Journal of Immunological Methods. 328:34-44
The clinical development of therapeutic proteins requires assays that measure the pharmacokinetic (PK) profile of, and the potential immune response (IR) to, the protein agent. Each assay requires reagents that are highly specific for the therapeutic
Autor:
Henry M. Sarau, James J. Foley, Torsten Crass, Robert S. Ames, Mark A. Tornetta, Jörg Köhl, Wilfried Bautsch, Andreas Klos
Publikováno v:
Journal of Biological Chemistry. 274:8367-8370
Chimeras were generated between the human anaphylatoxin C3a and C5a receptors (C3aR and C5aR, respectively) to define the structural requirements for ligand binding and discrimination. Chimeric receptors were generated by systematically exchanging be
Autor:
Cynthia B. Weston, Terence G. Porter, Ping Tsui, Carol Silverman, Robert S. Ames, Mark A. Tornetta, Sandra D. Griego, Raymond W. Sweet
Publikováno v:
Journal of immunological methods. 263(1-2)
Epitope-blocked panning is an approach to mining antigen-specific diversity from phage display antibody libraries. Previously, we developed and used this method to recover a neutralizing antibody to respiratory syncytial virus (RSV) by blocking a dom
Autor:
Karl F. Erhard, Andreas Klos, G. McCafferty, J. P. Hieble, Osborn Rr, A.C. Sulpizio, Alison M. Badger, Underwood Dc, Robert S. Ames, Adams Jl, James J. Foley, Wilfried Bautsch, R. D. Cousins, Keith W. Ward, William E. Bondinell, A. J. Jurewicz, Mark A. Tornetta, B. Settmacher, David Lee, Henry M. Sarau
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 166(10)
The anaphylatoxin C3a is a potent chemotactic peptide and inflammatory mediator released during complement activation which binds to and activates a G-protein-coupled receptor. Molecular cloning of the C3aR has facilitated studies to identify nonpept
Autor:
Robert S. Ames, Keith Deen, Ann M. Swift, Subinay Ganguly, Christopher S. Jones, Mark A. Tornetta
Publikováno v:
Journal of immunological methods. 184(2)
The use of combinatorial Ig libraries displayed on the surface of bacteriophage has advantages over traditional hybridoma techniques for the generation of mAbs but in many instances full length Igs may be more desirable than Fab fragments. Two murine