Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark A. Sirgo"'
Publikováno v:
American Journal of Therapeutics. 8:387-398
Introduction A study of the consumer's understanding of the product label instructions and the resulting product use were conducted to support the switch of a product from prescription to nonprescription status. H2 receptor antagonists have recently
Publikováno v:
American Journal of Therapeutics. 8:399-408
Background: Many Americans have heartburn or related symptoms monthly and >20% experience heartburn at least once per day. Although many self-treat episodic heartburn with nonprescription antacids, newer treatments that decrease gastric volume and in
Publikováno v:
Alimentary Pharmacology & Therapeutics. 13:475-481
Background : This was a randomized, double-blind, placebo-controlled, multicentre, parallel group, dose-ranging trial of ranitidine tablets for relief of episodic heartburn. Adult out-patients who reported heartburn relieved by antacids at least seve
Autor:
Benjamin O. Williams, Arthur A. Ciociola, Malijana Mandich, Kathy S. Buaron, J. Ellen Payne, Mark A. Sirgo, Lori A. Witham, Keith A. Pappa
Publikováno v:
Current Therapeutic Research. 59:454-466
Ranitidine 75 mg has been shown previously to be effective for the treatment of existing heartburn symptoms. In the present study, the efficacy and safety of ranitidine 75 mg in preventing or reducing heartburn symptoms were assessed when the study m
Autor:
H. Mitchell Perry, Mark A. Sirgo, Amy W. Peng, Deborah L. Due, Raymond R. Townsend, David W. Bartels, Joan Ryder Benz, John B. Kostis, W. Dallas Hall
Publikováno v:
The American Journal of Medicine. 96:77-86
purpose: This trial was designed to evaluate the efficacy and safety of three different classes of antihypertensive agents in elderly women. patients and methods: The trial had three phases: 4 to 8 weeks of placebo, 6 weeks of titration, and 16 weeks
Publikováno v:
The Journal of Clinical Pharmacology. 33:79-83
The authors conducted a retrospective review of 21 United States trials of ranitidine in acid peptic diseases and compared the adverse events in elderly (> or = 65 years) and nonelderly (< 65 years) patients. Ranitidine dosages ranged from 150 mg/day
Autor:
Mark A. Sirgo, Sandra Norris
Publikováno v:
DICP. 25:284-288
The disposition of drugs in the elderly is particularly relevant with antiinfectives, because this population has an increased risk of infections. Renal function deteriorates with age, yet dosage guidelines for antibiotics that allow for this reducti
Autor:
Seichi Oishi, William B. Applegate, Nemat O. Borhani, Paul M. Kaihlanen, Deborah L. Due, Vincent DeQuattro, Mark A. Sirgo
Publikováno v:
The American Journal of Medicine. 90:198-205
Purpose This study compared the safety and efficacy of labetalol and enalapril as antihypertensive therapy for elderly patients. Patients and methods A randomized, openlabel, parallel controlled trial was conducted. After completing a 4-week placebo
Publikováno v:
Clinical Pharmacology and Therapeutics. 48:375-380
Calcium antagonists have been shown to depress hepatic enzymes and accelerate hepatic blood flow. This study was designed to compare the effects of two calcium antagonists, isradipine and diltiazem, on antipyrine and indocyanine green (ICG) clearance
Publikováno v:
The Journal of Clinical Pharmacology. 30:524-532
The safety and efficacy of labetalol and hydrochlorothiazide (HCTZ) were compared in a group of 34 patients aged 65 years or older with mild to moderate essential hypertension. After a 4-week placebo run-in period, during which all previous antihyper