Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Mark A. Rizzacasa"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2762-2766 (2013)
The total synthesis of the endogenous inflammation resolving eicosanoid resolvin D2 (1) is described. The key steps involved a Wittig reaction between aldehyde 5 and the ylide derived from phosphonium salt 6 to give enyne 17 and condensation of the s
Externí odkaz:
https://doaj.org/article/1242fd16b235448f954d9fc14396c31a
Publikováno v:
ARKIVOC, Vol 2006, Iss 7, Pp 105-119 (2006)
Externí odkaz:
https://doaj.org/article/15daab140d4c45b3a92dcff892c919de
Autor:
Mina Salimimarand, Mark A. Rizzacasa
Publikováno v:
Organic & Biomolecular Chemistry. 21:1341-1355
This review details the biological activity, biosynthesis and synthesis of isochromanone metabolites isolated from myxobacteria.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64d8f4563f3e807cff8d661ea442ff7
https://doi.org/10.1039/d2ob01926d
https://doi.org/10.1039/d2ob01926d
Autor:
Michael Ricca, Wei Zhang, Jiaqi Li, Thomas Fellowes, Jonathan M. White, Paul S. Donnelly, Mark A. Rizzacasa
Publikováno v:
Organic & Biomolecular Chemistry. 20:4038-4047
The preparation of Co(ii) and Co(iii) SALPN type catalysts for the Mukaiyama hydration of enones, and their application to the synthesis of acyloin natural products is described. An acyloin rearrangement was key to the success of this approach.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68e8412d98539941c118f8213c84be7
https://doi.org/10.1039/d2ob00651k
https://doi.org/10.1039/d2ob00651k
Publikováno v:
The Journal of Organic Chemistry. 86:14223-14231
The development of a flow-assisted synthesis of alkyl citrate natural products is described. The flow route harnesses a number of steps including the generation of ketene silyl acetal, a formal [2 + 2] cycloaddition, and a methanolysis cascade to eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab440f9418dd05840d077553f20983d8
https://doi.org/10.1021/acs.joc.1c01645
https://doi.org/10.1021/acs.joc.1c01645
Publikováno v:
Organic Letters. 23:3557-3560
The total synthesis of viridiofungins A (1) and B (2) via β-lactone 3 in 13 steps is reported. Key steps included an HF-mediated rearrangement of cyclobutene diester 9 to form a bicyclic lactone 6, an olefin cross metathesis between disubstituted al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c7147509b753340bc7437684a62299
https://doi.org/10.1021/acs.orglett.1c00971
https://doi.org/10.1021/acs.orglett.1c00971
Autor:
Alex A Rafaniello, Mark A. Rizzacasa
Publikováno v:
Organic Letters. 22:1972-1975
The first total synthesis of the alkyl citrate trachyspic acid 19-n-butyl ester (1) is described. A formal [2 + 2]-cycloaddition of the silylketene acetal derived from lactone 6 with di-n-butylacetylene dicarboxylate 7 provided the cyclobutene dieste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3f643837f4373e5ed58d7e49622084
https://doi.org/10.1021/acs.orglett.0c00319
https://doi.org/10.1021/acs.orglett.0c00319
Autor:
Jessica L. Porter, Liam K. R. Sharkey, Mark A. Rizzacasa, Sacha J. Pidot, Liselle Atkin, Marion Herisse, Timothy P. Stinear, Torsten Seemann, Benjamin P Howden
Publikováno v:
Angewandte Chemie. 131:4036-4041
The nargenicin family of antibiotics are macrolides containing a rare ether-bridged cis-decalin motif. Several of these compounds are highly active against multi-drug resistant organisms. Despite the identification of the first members of this family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca1398ef50dff1efc17a6909f95eff4
https://doi.org/10.1002/ange.201900290
https://doi.org/10.1002/ange.201900290
Autor:
Michael Ricca, Mark A. Rizzacasa, Paul S. Donnelly, Jonathan M. White, Andrea J. North, Angus Robertson, Natalia Caren Radjah
Publikováno v:
Chemical Communications. 55:7699-7702
Two cis-β-MnIIISALPN catalysts were synthesised and tested in the Mukaiyama–Isayama hydration of α,β-unsaturated esters. The MnIIIEtOSALPN(acac) complex 7 is the most active and catalyses hydration with little or no detectable undesired alkene r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61ba7e8c6c3e1ad15bbba9dbb0e2e8c
https://doi.org/10.1039/c9cc03921j
https://doi.org/10.1039/c9cc03921j
Autor:
Michael Ricca, Mark A. Rizzacasa
Publikováno v:
Organicbiomolecular chemistry. 19(13)
This review details the isolation, biosynthesis, biological activity and synthesis of spiroacetals from the myxobacterium Sorangium cellulosum. The strategies utilised to access the challenging structures and stereochemistry of these natural products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4342f203d5c6e80749ebce06ec182369
https://pubmed.ncbi.nlm.nih.gov/33683270
https://pubmed.ncbi.nlm.nih.gov/33683270