Clinical challenges in diagnosis and treatment of recurrent vulvovaginal candidiasis

Autor: Chemen M Neal, Mark G Martens

Publikováno v: SAGE Open Medicine, Vol 10 (2022)

Vulvovaginal candidiasis is a common infection associated most often with the overgrowth of the fungal species Candida albicans . Although most women will have at least one episode of vulvovaginal candidiasis in their lifetime, some will experience r

Externí odkaz: https://doaj.org/article/1500161dd64c474599452fa448370c28

Probiotics: insights and new opportunities for Clostridioides difficile intervention

Autor: Rusha Pal, Ahmad I. M. Athamneh, Riddhi Deshpande, Jose A. R. Ramirez, Kayode T. Adu, Pushpanathan Muthuirulan, Shrikant Pawar, Manuele Biazzo, Yiorgos Apidianakis, Ulrik Kraemer Sundekilde, Cesar de la Fuente-Nunez, Mark G. Martens, George P. Tegos, Mohamed N. Seleem

Publikováno v: Pal, R, Athamneh, A I M, Deshpande, R, Ramirez, J A R, Adu, K T, Muthuirulan, P, Pawar, S, Biazzo, M, Apidianakis, Y, Sundekilde, U K, de la Fuente-Nunez, C, Martens, M G, Tegos, G P & Seleem, M N 2023, ' Probiotics: insights and new opportunities for Clostridioides difficile intervention ', Critical Reviews in Microbiology, vol. 49, no. 3, pp. 414-434 . https://doi.org/10.1080/1040841X.2022.2072705

Clostridioides difficile infection (CDI) is a life-threatening disease caused by the Gram-positive, opportunistic intestinal pathogen C. difficile. Despite the availability of antimicrobial drugs to treat CDI, such as vancomycin, metronidazole, and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d773c9178274d537e65419a4cf2708
https://doi.org/10.1080/1040841x.2022.2072705

Phase 3 study evaluating the safety and efficacy of oteseconazole in the treatment of recurrent vulvovaginal candidiasis and acute vulvovaginal candidiasis infections

Autor: Mark G. Martens, Bassem Maximos, Thorsten Degenhardt, Karen Person, Stacey Curelop, Mahmoud Ghannoum, Amy Flynt, Stephen R. Brand

Publikováno v: American Journal of Obstetrics and Gynecology. 227:880.e1-880.e11

Recurrent vulvovaginal candidiasis affects nearly 138 million women globally each year. In the United States, fluconazole is considered the standard of care for acute vulvovaginal candidiasis, but until recently there was no US Food and Drug Administ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ace389f8ba574e1944a46db51970218
https://doi.org/10.1016/j.ajog.2022.07.023

107. A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Oteseconazole (VT-1161) Oral Capsules versus Fluconazole and Placebo in the Treatment of Acute Vulvovaginal Candidiasis Episodes in Subjects with Recurrent Vulvovaginal Candidiasis (ultraViolet)

Autor: Mark G Martens, Bassem Maximos, Thorsten Degenhardt, Karen Person, Stacey Curelop, Mahmoud Ghannoum, Stephen Brand

Publikováno v: Open Forum Infectious Diseases

Background Recurrent vulvovaginal candidiasis (RVVC) affects nearly 138 million women globally each year. Currently there are no FDA approved treatments. The study was conducted to evaluate the efficacy of oral oteseconazole (VT-1161) in the preventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827c53af0e8cf79fe97ce2ba8a031f8e
http://europepmc.org/articles/PMC8644338

Preterm Labor and Maternal Hypoxia in Patients With Community-Acquired Pneumonia

Autor: Maurizio L. Maccato, Phillip Pinell, Mark G. Martens, Sebastian Faro

Publikováno v: Infectious Diseases in Obstetrics and Gynecology, Vol 4, Iss 4, Pp 221-224 (1996)

Objective: We sought to determine if preterm labor is associated with the degree of maternal hypoxia in pregnant women with community-acquired pneumonia but no other maternal diseases.

Externí odkaz: https://doaj.org/article/ee67c2db6fab4ad9abf29263189f636f