Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mark A. Hatcher"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 162-162 (2024)
OBJECTIVES/GOALS: We are investigating the role of IL-6 in regulating renal function by measuring mean arterial pressure (MAP), renal plasma flow (RPF) and glomerular filtration rate (GFR) in wild type (WT) and IL-6-knockout (KO) mice in established
Externí odkaz:
https://doaj.org/article/a7c70422664a48b3b46ef24f7ce89517
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 112-112 (2023)
OBJECTIVES/GOALS: Approximately 37 million people in the U.S. have chronic kidney disease, which is a major risk factor for cardiovascular and end stage renal diseases. PPAR-αknockout (KO) mice exhibit increased renal inflammation and blood pressu
Externí odkaz:
https://doaj.org/article/2d21d7556ced462fa3801edeeafef6e7
Autor:
Mark A. Hatcher, Michel Journet, Shiping Xie, John A. Kowalski, Tom C Lovelace, Greg A. Erickson, Christopher J. Pink
Publikováno v:
The Journal of organic chemistry. 87(4)
A novel oxidative activation of a thiolactam was developed for the preparation of methyltriazolo[1,4]benzodiazepine in a single step. A sulfenic acid (R-SOH) was proposed as the activated intermediate with the concurrent formation of acetylhydrazone
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2011 (2011)
We studied healthy males challenged with a 900 Cal test beverage and correlated EE with the raw (ms2) and normalized units (nu) of total power (TP), low frequency/high frequency (LF/HF) and VLF spectral power of heart rate variability (HRV). The corr
Externí odkaz:
https://doaj.org/article/a97e4df9831248b4a64d30f401d26cbc
Publikováno v:
Tetrahedron. 72:6025-6030
In this report, several new epoxide examples were united with β-silyl ketone enolates for the construction, after oxidative fragmentation, of ring expanded lactones, n+3 atoms in size. Importantly, azido lactones were found to be valuable in an exte
Autor:
Joanne S. Allard, Camille Wilson, Milan Poindexter, Linda Boadi, Ihori Kobayashi, Mark D. Hatcher, Eva K. Polston
Publikováno v:
Behav Brain Res
Women are at greater risk than men for developing posttraumatic stress disorder (PTSD) after trauma exposure. Sleep, especially rapid-eye-movement sleep (REMS), has been considered a contributing factor to the development of PTSD symptoms through its
Publikováno v:
Biological Control. 64:276-282
The degree to which invasive quagga mussels have spread across the Southwestern United States is unprecedented, and until now, none of the controls currently available is risk-free to the environment or human health. Here we demonstrate that stocking
Autor:
B. Liu, Vassil I. Elitzin, J. Powers, Daniel E. Patterson, Roman Davis, Elie Amine Tabet, Chong Pek Yoke, Matthew Salmons, M. Toczko, Mark A. Hatcher, Kae M. Bullock, M. Jackson
Publikováno v:
Topics in Catalysis. 55:446-452
Transition metal catalysis by Cu (CF3Cu), Ir (C–H activation), and Ru (ring-closing metathesis) were applied to prepare a complicated tetra substituted pyrazolopyridine drug candidate at GlaxoSmithKline. CuI/FSO2CF2CO2Me was utilized to install a C
Autor:
Mezbah U. Faruque, Ronald E. DeMeersman, Rachel E. Austin, Brian M. Hickey, Vernon Bond, Mark D. Hatcher, Kim L. Goring, Richard M. Millis
Publikováno v:
Life Sciences. 86:153-157
We tested the hypothesis that body fat percentage determines cardiac sympathovagal balance in healthy subjects.Heart rate variability (HRV) measurements were made of the standard deviation of the normal-normal RR intervals (SDNN) and the low frequenc
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 6:53-71
Deltanoids are the class of compounds comprising all natural and synthetic vitamin D molecules. The anti-proliferative, pro-differentiation, and pro-apoptotic properties of deltanoids have garnered interest in the fields of cancer chemoprevention and