Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mark A. Halloran"'
Autor:
Julie D. Atkin, Ian P. Blair, Audrey Ragagnin, Gilles J. Guillemin, Natalie Grima, Sonam Parakh, Shu Yang, Kai-Ying Soo, Mark A. Halloran, Hamideh Shahheydari, Vinod Sundaramoorthy, Benjamin Heng, Marta Vidal
Publikováno v:
Cellular and molecular life sciences : CMLS. 77(19)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative diseases that are related genetically and pathologically. Mutations in the UBQLN2 gene, encoding the ubiquitin-like protein ubiquilin2, are associated w
Autor:
Reka P. Toth, Peter Lock, Julie D. Atkin, Sonam Parakh, Mark A. Halloran, Katherine A. Southam, Catriona McLean, Vinod Sundaramoorthy, Manal A. Farg, Anna E. King, Kai-Ying Soo
Publikováno v:
Acta Neuropathologica. 130:679-697
Several diverse proteins are linked genetically/pathologically to neurodegeneration in amyotrophic lateral sclerosis (ALS) including SOD1, TDP-43 and FUS. Using a variety of cellular and biochemical techniques, we demonstrate that ALS-associated muta
Autor:
Rachel A.K. Atkinson, Mark A. Halloran, Manal A. Farg, Jessica M. Sultana, Anna E. King, Shu Yang, Julie D. Atkin, Kai Y. Soo, Vinod Sundaramoorthy, Vita Levina, Ian P. Blair, Paul A. Gleeson
Publikováno v:
Human Molecular Genetics
Intronic expansion of a hexanucleotide GGGGCC repeat in the chromosome 9 open reading frame 72 (C9ORF72) gene is the major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. However, the cellular function of the C9ORF7
Publikováno v:
International Journal of Cell Biology, Vol 2013 (2013)
International Journal of Cell Biology
International Journal of Cell Biology
Neurodegenerative diseases involve the progressive loss of neurons, and a pathological hallmark is the presence of abnormal inclusions containing misfolded proteins. Although the precise molecular mechanisms triggering neurodegeneration remain unclea
Autor:
Manal A. Farg, Mark A. Halloran, Malcolm K. Horne, Phillip Nagley, Julie D. Atkin, Bradley J. Turner, Kai-Ying Soo, Adam K. Walker
Publikováno v:
Journal of neurochemistry. 129(1)
Cu/Zn-superoxide dismutase is misfolded in familial and sporadic amyotrophic lateral sclerosis, but it is not clear how this triggers endoplasmic reticulum (ER) stress or other pathogenic processes. Here, we demonstrate that mutant SOD1 (mSOD1) is pr
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2013 (2013)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results from the death of upper and lower motor neurons. Due to a lack of effective treatment, it is imperative to understand the underlying mechanisms and processes involved in
Autor:
Mark A. Halloran, Anna Kokavec
Publikováno v:
Canadian journal of physiology and pharmacology. 88(12)
The aim in the present study was to assess the effect of small-moderate red wine ingestion on the level of serum insulin and plasma glucose when nutritional status is varied. Twenty nondiabetic males (19–22 years) participated in the study. In the
Autor:
Mark J. Halloran
Publikováno v:
Journal of Product Innovation Management. 9:183-184
Autor:
Mark J. Halloran
Publikováno v:
Journal of Product Innovation Management. 9:184-185
Publikováno v:
Vox Sanguinis. 6:287-292