Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Mark A. Goodman"'
Publikováno v:
Sarcoma, Vol 2012 (2012)
In previous reports, patients with Ewing's sarcoma received radiation therapy (XRT) for definitive local control because metastatic disease and pelvic location were thought to preclude aggressive local treatment. We sought to determine if single-site
Externí odkaz:
https://doaj.org/article/da760ef3051e4c6299c5f2f4ab4716ff
Autor:
Ephraim E. Parent, Dhruv Patel, Jonathon A. Nye, Zhuo Li, Jeffrey J. Olson, David M. Schuster, Mark M. Goodman
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Background Stereotactic radiosurgery (SRS) is often the primary treatment modality for patients with intracranial metastatic disease. Despite advances in magnetic resonance imaging, including use of perfusion and diffusion sequences and mole
Externí odkaz:
https://doaj.org/article/d7ff5e2e51cb449fa3d40041325c3f10
Autor:
Valerie Joers, Gunasingh Masilamoni, Doty Kempf, Alison R. Weiss, Travis M. Rotterman, Benjamin Murray, Gul Yalcin-Cakmakli, Ronald J. Voll, Mark M. Goodman, Leonard Howell, Jocelyne Bachevalier, Stefan J. Green, Ankur Naqib, Maliha Shaikh, Phillip A. Engen, Ali Keshavarzian, Christopher J. Barnum, Jonathon A. Nye, Yoland Smith, Malú G. Tansey
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105027- (2020)
Inflammation has been linked to the development of nonmotor symptoms in Parkinson's disease (PD), which greatly impact patients' quality of life and can often precede motor symptoms. Suitable animal models are critical for our understanding of the me
Externí odkaz:
https://doaj.org/article/43c19177d7114cb980da723d241e3f02
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Focal amplifications (FA) can mediate targeted therapy resistance in cancer. Understanding the structure and dynamics of FAs is critical for designing treatments that overcome plasticity-mediated resistance. We developed a melanoma model of dual MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005496410afa192ef817de39cbb29907
https://doi.org/10.1158/2159-8290.c.6549616.v1
https://doi.org/10.1158/2159-8290.c.6549616.v1
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Supplementary Table from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a8c4bd05ca644172e944aa05c3ccc9
https://doi.org/10.1158/2159-8290.22541326
https://doi.org/10.1158/2159-8290.22541326
Autor:
Thomas G. Graeber, Roger S. Lo, Vineet Bafna, Daniel S. Peeper, Asha S. Multani, P. Nagesh Rao, Paul J. Hergenrother, Kim H. Paraiso, T. Niroshi Senaratne, Stephen E. Motika, Amelia Palermo, Johanna ten Hoeve, Kyle Sheu, Salwan Alhani, Nikolas G. Balanis, Rachana Jayaraman, Gabriel Karin, Eli Pazol, Jesus Salazar, William P. Crosson, Trevor Ridgley, Prashanthi Dharanipragada, Oscar Krijgsman, Gatien Moriceau, Mark H. Goodman, Jens Luebeck, Shirley H. Lomeli, Siavash R. Dehkordi, Arthur Huang, Jenna K. Minami, Kai Song
Supplementary Figure from Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ca04ff69af6e06a7f3fc1472e95733
https://doi.org/10.1158/2159-8290.22541341
https://doi.org/10.1158/2159-8290.22541341
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 285K, Supplementary Figure 1. Synthetic scheme and purity of KCN1 3,4-dimethoxy-N-(2,2-dimethyl-2H-chromen-6-yl)methyl-N-phenylbenzenesulfonamide. Supplementary Figure 2. KCN1 is chemically stable in cell culture medium under normoxic or hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5604fa82bef743c03483a070486941
https://doi.org/10.1158/1078-0432.22451897.v1
https://doi.org/10.1158/1078-0432.22451897.v1
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
Purpose: The hypoxia-inducible factor-1 (HIF-1) plays a critical role in tumor adaptation to hypoxia, and its elevated expression correlates with poor prognosis and treatment failure in patients with cancer. In this study, we determined whether 3,4-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb323e17c5a0b8e7a7bc068b430613e
https://doi.org/10.1158/1078-0432.c.6522323
https://doi.org/10.1158/1078-0432.c.6522323
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 106K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e87de02930b9a303fe64ab33cfcc548
https://doi.org/10.1158/1078-0432.22451900
https://doi.org/10.1158/1078-0432.22451900
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 591K, Supplementary Figure 4. KCN1 inhibits the growth of pre-established human glioblastoma s.c. xenografts. Supplementary Figure 5. Effect of KCN1 treatment on mice weight. Supplementary Figure 6. Chronic systemic KCN1 administration show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3746120f1e5c5a2e32f51772ecf87422
https://doi.org/10.1158/1078-0432.22451894.v1
https://doi.org/10.1158/1078-0432.22451894.v1