Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mark A. Gilchrist"'
Autor:
Richard C. Wilson, Alaa Riezk, Paul Arkell, Damien Ming, Ryan Armiger, Victoria Latham, Mark J. Gilchrist, Anne-Grete Märtson, William W. Hope, Alison H. Holmes, Timothy M. Rawson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In the face of increasing antimicrobial tolerance and resistance there is a global obligation to optimise oral antimicrobial dosing strategies including narrow spectrum penicillins, such as penicillin-V. We conducted a randomised, crossover
Externí odkaz:
https://doaj.org/article/97703b0946e84335a208e8fd496377c1
Autor:
Julien Papillon, Mark A. Gilchrist, Meihui Pan, Alok K. Singh, James Thompson, Margaret E. Brousseau, Changgang Lou, Todd Stawicki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3514-3517
We designed and prepared synthetic phospholipids that generate lyso-phosphatidylcholine products with a unique mass for convenient detection by LC-MS in complex biological matrices. We demonstrated that compound 4, formulated either as a Triton X-100
Publikováno v:
SLAS Discovery. 13:486-493
Fluorescent detection of calcium mobilization has been used successfully to identify modulators of G-protein-coupled receptors (GPCRs); however, inherent issues with fluorescence may limit its potential for high-throughput screening miniaturization.