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pro vyhledávání: '"Mark A. Engelhardt"'
Autor:
Mark A. Engelhardt
Publikováno v:
Technology Innovation Management Review, Vol 7, Iss 10, Pp 22-34 (2017)
Health services must balance patient care with information privacy, access, and completeness. The massive scale of the healthcare industry also amplifies the importance of cost control. The promise of blockchain technology in health services, combine
Externí odkaz:
https://doaj.org/article/55cb28b9df9344efb2f061dee67e861f
Publikováno v:
Community Mental Health Journal. 50:474-479
Assertive community treatment (ACT) and integrated dual disorders treatment (IDDT) have individually proven effective for treatment of adults with complex behavioral health and housing needs. This study evaluated the effectiveness of an ACT team that
Comprehensive, Continuous, Integrated System of Care Development: Tampa-Hillsborough County, Florida
Publikováno v:
Journal of Dual Diagnosis. 5:110-116
A local system within what is usually termed the Suncoast Region of southwest Florida, Hillsborough County, which includes the city of Tampa, has long been recognized as one of the more innovative ...
Autor:
Mark A. Engelhardt, Daniel Herschlag, Rhiju Das, Hyejean Suh, Alain Laederach, Rick Russell, Kevin J. Travers
Publikováno v:
Journal of Molecular Biology. 363:531-544
Like many structured RNAs, the Tetrahymena group I ribozyme is prone to misfolding. Here we probe a long-lived misfolded species, referred to as M, and uncover paradoxical aspects of its structure and folding. Previous work indicated that a non-nativ
Publikováno v:
Journal of Molecular Biology. 317:493-506
Simulations of an RNA hairpin containing a GNRA tetraloop were conducted to allow the characterization of its secondary structure formation and dynamics. Ten 10 ns trajectories of the folded hairpin 5′-GGGC[GCAA]GCCU-3′ were generated using stoch
Autor:
Daniel Herschlag, Jennifer A. Doudna, Mark A. Engelhardt, Deborah S. Knitt, Elizabeth A. Doherty
Publikováno v:
Biochemistry. 39:2639-2651
Phylogenetic comparisons and site-directed mutagenesis indicate that group I introns are composed of a catalytic core that is universally conserved and peripheral elements that are conserved only within intron subclasses. Despite this low overall con