Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mark A. Endsley"'
Autor:
Alex J. Holloway, Tais B. Saito, Kubra F. Naqvi, Matthew B. Huante, Xiuzhen Fan, Joshua G. Lisinicchia, Benjamin B. Gelman, Janice J. Endsley, Mark A. Endsley
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an established model of HIV infection, but defects in immune tissue reconstitution remain a ch
Externí odkaz:
https://doaj.org/article/6b210dbcdb27465b8b11fb6325b97717
Autor:
Sadhana Chauhan, Rebecca J. Nusbaum, Matthew B. Huante, Alex J. Holloway, Mark A. Endsley, Benjamin B. Gelman, Joshua G. Lisinicchia, Janice J. Endsley
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 6, p 129 (2024)
L-arginine metabolism is strongly linked with immunity to mycobacteria, primarily through the antimicrobial activity of nitric oxide (NO). The potential to modulate tuberculosis (TB) outcomes through interventions that target L-arginine pathways are
Externí odkaz:
https://doaj.org/article/fcdde219cac24a639c2dea6cb1679b64
Autor:
Philipp A. Ilinykh, Sivakumar Periasamy, Kai Huang, Natalia A. Kuzmina, Palaniappan Ramanathan, Michelle N. Meyer, Chad E. Mire, Ivan V. Kuzmin, Preeti Bharaj, Jessica R. Endsley, Maria Chikina, Stuart C. Sealfon, Steven G. Widen, Mark A. Endsley, Alexander Bukreyev
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Respiratory tract vaccination has an advantage of needle-free delivery and induction of mucosal immune response in the portal of SARS-CoV-2 entry. We utilized human parainfluenza virus type 3 vector to generate constructs expressing the full
Externí odkaz:
https://doaj.org/article/f7f896e4aff94be8a7c13063d10aa8bd
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Humanized mice have become an important workhorse model for HIV research. Advances that enabled development of a human immune system in immune deficient mouse strains have aided new basic research in HIV pathogenesis and immune dysfunction.
Externí odkaz:
https://doaj.org/article/50758e105aea46e1b3821d4891fea15b
Autor:
Matthew B. Huante, Tais B. Saito, Rebecca J. Nusbaum, Kubra F. Naqvi, Sadhana Chauhan, Robert L. Hunter, Jeffrey K. Actor, Jai S. Rudra, Mark A. Endsley, Joshua G. Lisinicchia, Benjamin B. Gelman, Janice J. Endsley
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased risk of drug resistance development. Concurrent infection with HIV, including in those rece
Externí odkaz:
https://doaj.org/article/cd4e3d98969049a594a05d8680fa4ed0
Autor:
Shaobo Wang, Alex E. Clark, Shashi Kant Tiwari, Tariq M. Rana, Davey M. Smith, Sarah E. Huff, Mark A. Endsley, Matthew B. Huante, Aaron F. Carlin, William Bray, Indrasena Reddy Kummetha
Publikováno v:
Journal of medicinal chemistry, vol 65, iss 4
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
The emergence of a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents an urgent public health crisis. Without available targeted therapies, treatment options remain limited for COVID-19 patients. Using medicinal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3dd58568c15aa15aaf19657cc538c
https://escholarship.org/uc/item/5s74v314
https://escholarship.org/uc/item/5s74v314
Autor:
Benjamin B. Gelman, Kubra F. Naqvi, Taís Berelli Saito, Janice J. Endsley, Matthew B. Huante, Mark A. Endsley
Publikováno v:
J Immunol
Tuberculosis (TB) caused by infection with Mycobacterium tuberculosis is characterized by inflammatory pathology and poorly understood mechanisms of innate immunity. Pattern recognition receptors, expressed on the surface of macrophages, determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44a0c35a346d798f61c48822d717deb
https://europepmc.org/articles/PMC8702441/
https://europepmc.org/articles/PMC8702441/
Publikováno v:
Retrovirology
Retrovirology, Vol 18, Iss 1, Pp 1-14 (2021)
Retrovirology, Vol 18, Iss 1, Pp 1-14 (2021)
Humanized mice have become an important workhorse model for HIV research. Advances that enabled development of a human immune system in immune deficient mouse strains have aided new basic research in HIV pathogenesis and immune dysfunction. The small
Autor:
Jimin Xu, Jia Zhou, Jeffrey D. Cirillo, Mark A. Endsley, Janice J. Endsley, Xiu Zhen Fan, Megan A. Files
Publikováno v:
Tuberculosis (Edinburgh, Scotland)
The human immunodeficiency virus (HIV) pandemic is driving the re-emergence of tuberculosis (TB) as a global health threat, both by increasing the susceptibility of HIV-infected people to infection with Mycobacterium tuberculosis (Mtb), and increasin
Autor:
Netanya S. Utay, Heather L. Stevenson, Monique R. Ferguson, Anoma Somasunderam, Omar A. Saldarriaga, Min Kyung Yi, Heidi Spratt, Abdellah Akil, Mark A. Endsley, Saravanabalaji Shanmugam
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Retrospective studies indicate that co-infection of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) accelerates hepatic fibrosis progression. We have developed a co-culture system (MLH) comprising primary macrophages, hepatic stellate