Zobrazeno 1 - 10
of 1 397
pro vyhledávání: '"Mark A. Chen"'
Autor:
Julie Lei Zhu, Rasmus Schülke, Deniz Vatansever, Dayou Xi, Junjie Yan, Hanqing Zhao, Xiaohua Xie, Jianfeng Feng, Mark Yuting Chen, Barbara Jacquelyn Sahakian, Shouyan Wang
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Emerging evidence shows that the coronavirus disease 2019 (COVID-19) pandemic is negatively affecting mental health around the globe. Interventions to alleviate the psychological impact of the pandemic are urgently needed. Whether mindfulnes
Externí odkaz:
https://doaj.org/article/9bde3ed385fb42a1bdf45c6608416317
Autor:
Fransiskus X. Ivan, Xinrui Zhou, Suk Hiang Lau, Shamima Rashid, Jasmine S.M. Teo, Hong Kai Lee, Evelyn S. Koay, Kwai Peng Chan, Yee Sin Leo, Mark I.C. Chen, Chee Keong Kwoh, Vincent T. Chow
Publikováno v:
International Journal of Infectious Diseases, Vol 90, Iss , Pp 84-96 (2020)
Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificit
Externí odkaz:
https://doaj.org/article/3306aba6cf884746a7e37e1c14eafa98
Autor:
Ching-Tang Chang, MD, Wen-Hsien Lee, MD, Hsuan-Fu Kuo, MD, Mark Z. Chen, PhD, Po-Chao Hsu, MD, Chih-Sheng Chu, MD, Ho-Ming Su, MD, Tsung-Hsien Lin, MD, Hsueh-Wei Yen, MD, Cheng-An Chiu, MD
Publikováno v:
JACC: Case Reports, Vol 1, Iss 5, Pp 792-795 (2019)
Stumpless chronic total occlusion is associated with a higher failure rate of recanalization. Intravascular ultrasound (IVUS) is useful for identifying the entry point; however, 8-F guide catheters are necessary for real-time IVUS-guided wiring. This
Externí odkaz:
https://doaj.org/article/f8f640c1f4af494cafd0a2fe3d1a93ee
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1088 (2022)
In response to declining vaccine-induced immunity and the emergence of new COVID-19 variants, COVID-19 booster vaccination programmes have been widely launched in several high-income countries. However, public response has been slow, and scepticism a
Externí odkaz:
https://doaj.org/article/4bfbc5f738594d81bffd341d16c3daa3
Autor:
Valeria Yartseva, Leonard D. Goldstein, Julia Rodman, Lance Kates, Mark Z. Chen, Ying-Jiun J. Chen, Oded Foreman, Christian W. Siebel, Zora Modrusan, Andrew S. Peterson, Ana Jovičić
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1491-1503.e6 (2020)
Summary: How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell fate decisions has been the difficulty of
Externí odkaz:
https://doaj.org/article/369f10c9eb574d9880366d27d4b09e96
Autor:
Hui Zhang, Qinyu Zhu, Jixin Cui, Yuxin Wang, Mark J. Chen, Xing Guo, Vincent S. Tagliabracci, Jack E. Dixon, Junyu Xiao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Fam20 proteins are kinases that phosphorylate secreted proteins and proteoglycans. Here the authors present the crystal structures of the three Fam20 kinases and their complexes and give mechanistic insights into substrate recognition and the functio
Externí odkaz:
https://doaj.org/article/17af4b3603344b87a364eec04b64111a
Autor:
Konstadina Griva, Kevin Y. K. Tan, Frederick H. F. Chan, Ramanathan Periakaruppan, Brenda W. L. Ong, Alexius S. E. Soh, Mark IC. Chen
Publikováno v:
Vaccines, Vol 9, Iss 12, p 1415 (2021)
COVID-19 vaccines are crucial for achieving sufficient immunisation coverage to manage the pandemic, but vaccine hesitancy persists. This study aimed to investigate the prevalence and determinants of vaccine hesitancy in adults and in parents for vac
Externí odkaz:
https://doaj.org/article/deeba02bdd67416c83c14434761dca68
Autor:
Mark Z. Chen, Joshua C. Chang, Jose Zavala-Solorio, Lance Kates, Minh Thai, Annie Ogasawara, Xiaobo Bai, Sean Flanagan, Victor Nunez, Khanhky Phamluong, James Ziai, Robert Newman, Søren Warming, Ganesh Kolumam, Junichiro Sonoda
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1454-1467 (2017)
Objective: Fibroblast Growth Factor 21 (FGF21) is a potent stimulator of brown fat thermogenesis that improves insulin sensitivity, ameliorates hepatosteatosis, and induces weight loss by engaging the receptor complex comprised of Fibroblast Growth F
Externí odkaz:
https://doaj.org/article/ce235e57c3334e8584b6bcb64b10b27e
Publikováno v:
Protein & Cell, Vol 8, Iss 4, Pp 255-272 (2017)
ABSTRACT The 26S proteasome at the center of the ubiquitin-proteasome system (UPS) is essential for virtually all cellular processes of eukaryotes. A common misconception about the proteasome is that, once made, it remains as a static and uniform com
Externí odkaz:
https://doaj.org/article/9c0e3229897e42b7bad97d5523622304
Autor:
Giovanni Quarato, Luigi Mari, Nicholas J. Barrows, Mao Yang, Sebastian Ruehl, Mark J. Chen, Cliff S. Guy, Jonathan Low, Taosheng Chen, Douglas R. Green
Publikováno v:
Science Advances. 9
Degradation of defective mitochondria is an essential process to maintain cellular homeostasis and it is strictly regulated by the ubiquitin-proteasome system (UPS) and lysosomal activities. Here, using genome-wide CRISPR and small interference RNA s