Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Mark A. Belsey"'
Publikováno v:
Neurochemical Research. 32:1940-1949
Cell swelling is associated with the activation of an increase in the osmosensitive taurine release (OTR) rate, which serves to decrease cell volume as part of a process known as regulatory volume decrease. OTR, which is sensitive to many pharmacolog
Increased uptake of biologics in historically small molecule blockbuster-dominated therapeutic areas
Autor:
Mark J. Belsey, Duncan Emerton
Publikováno v:
Journal of Commercial Biotechnology. 13:48-51
The two leading therapeutic areas for biologic products, in terms of current sales and pipeline focus, are oncology and AIID (arthritis, immune and inflammatory disorders). Datamonitor has recently analysed these markets. 1, 2 Biologics designed to t
Publikováno v:
Journal of Commercial Biotechnology. 12:150-155
Following flu vaccine manufacturing and supply issues in the USA and the global threat of an avian flu pandemic, the flu market is attracting considerable interest. This market was worth approximately US$1.1bn in 2004, and it is expected to grow to U
Autor:
John Savopoulos, Mark J. Belsey
Publikováno v:
Journal of Medical Marketing. 6:6-11
Autor:
Mark J. Belsey, Alex K Pavlou
Publikováno v:
Journal of Commercial Biotechnology. 11:369-373
As part of Datamonitor's alliance and licensing strategic analysis, the authors have completed a two year survey of the trends underlying early-stage drug discovery and development collaborations between October 2002 and September 2004, which include
Autor:
Alex K Pavlou, Mark J. Belsey
Publikováno v:
Journal of Commercial Biotechnology. 11:275-278
The DNA/RNA market is currently at an early stage of development, with only two marketed products that together generated an estimated US$30m in 2004. The launch of Pfizer/Eyetech's ophthalmological aptamer Macugen (pegaptanib) is set to help power m
Autor:
Alex K Pavlou, Mark J. Belsey
Publikováno v:
Journal of Commercial Biotechnology. 11:171-175
Datamonitor analysis has identified two key company categories currently shaping the biotech industry: the leading biotherapeutics players and the emerging biotherapeutics players. Analysis of financial trends of companies in these categories from 20
Publikováno v:
Annals of the New York Academy of Sciences. 1028:38-55
Key elements of tumor development include proliferation, migration, invasiveness, and angiogenesis. Activation of the volume-sensitive organic osmolyte/anion channel (VSOAC) has been suggested to play a role in all of these processes. VSOACs may ther
Autor:
Alex K Pavlou, Mark J. Belsey
Publikováno v:
Journal of Commercial Biotechnology. 11:80-86
Datamonitor analysis recognises 18 biological brands that are expected to drive sales within the biopharma sector. The group includes 12 recombinant DNA proteins and six antibodies which are forecast to generate sales of US$29.0bn and US$13.2bn by 20
Publikováno v:
European Journal of Pharmacology. 474:185-193
FACS analysis and [14C]-taurine efflux were used to determine whether activation of the volume-sensitive organic osmolyte/anion channel plays a role in cell cycle progression. This was achieved by examining the effects of a collection of (i) H(1) ant