Zobrazeno 1 - 10
of 2 015
pro vyhledávání: '"Mark A. Adams"'
Autor:
Candice N. Baker, Debra Duso, Nagarama Kothapalli, Tricia Hart, Sean Casey, Tres Cookenham, Larry Kummer, Janine Hvizdos, Kathleen Lanzer, Purva Vats, Priya Shanbhag, Isaac Bell, Mike Tighe, Kelsey Travis, Frank Szaba, Jeffrey M. Harder, Olivia Bedard, Natalie Oberding, Jerrold M. Ward, Mark D. Adams, Cathleen Lutz, Shelton S. Bradrick, William W. Reiley, Nadia A. Rosenthal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Mutations in SARS-CoV-2 variants of concern (VOCs) have expanded the viral host range beyond primates, and a few other mammals, to mice, affording the opportunity to exploit genetically diverse mouse panels to model the broad spectrum of res
Externí odkaz:
https://doaj.org/article/2c9c9826453141688a649f8f972e01a2
Autor:
Habib Sadeghirad, James Monkman, Chin Wee Tan, Ning Liu, Joseph Yunis, Meg L. Donovan, Afshin Moradi, Niyati Jhaveri, Chris Perry, Mark N. Adams, Ken O’Byrne, Majid E. Warkiani, Rahul Ladwa, Brett G.M. Hughes, Arutha Kulasinghe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) generally has a poor prognosis for patients with limited treatment options. While incorporating immune checkpoint inhibitors (ICIs) has now become the standard
Externí odkaz:
https://doaj.org/article/f1dddeab14594adbaeaca19710053a73
Autor:
Mark A. Adams, Mathias Neumann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/93a6899317d54363909e3227273d86d9
Autor:
Christopher P. Krieg, Duncan D. Smith, Mark A. Adams, Jens Berger, Niloofar Layegh Nikravesh, Eric J. von Wettberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Global climate change and land use change underlie a need to develop new crop breeding strategies, and crop wild relatives (CWR) have become an important potential source of new genetic material to improve breeding efforts. Many recent appro
Externí odkaz:
https://doaj.org/article/2ad84d13ce354a04ab74bd7901bc95ea
Autor:
Tabassum Khair Barbhuiya, Sam Beard, Esha T. Shah, Steven Mason, Emma Bolderson, Ken O’Byrne, Luke W. Guddat, Derek J. Richard, Mark N. Adams, Neha S. Gandhi
Publikováno v:
ACS Omega, Vol 9, Iss 7, Pp 8362-8373 (2024)
Externí odkaz:
https://doaj.org/article/980348c0606c4f249eee8b785d64abc2
Autor:
Maddison Rose, Joshua T. Burgess, Chee Man Cheong, Mark N. Adams, Parastoo Shahrouzi, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundTriple-negative breast cancer (TNBC) is a sub-classification of breast carcinomas, which leads to poor survival outcomes for patients. TNBCs do not possess the hormone receptors that are frequently targeted as a therapeutic in other cancer
Externí odkaz:
https://doaj.org/article/730fd40bf05e413cbdb093bdcca0200a
Autor:
Duncan D. Smith, Mark A. Adams, Amanda M. Salvi, Christopher P. Krieg, Cécile Ané, Katherine A. McCulloh, Thomas J. Givnish
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Tradeoffs between the energetic benefits and costs of traits can shape species and trait distributions along environmental gradients. Here we test predictions based on such tradeoffs using survival, growth, and 50 photosynthetic, hydraulic,
Externí odkaz:
https://doaj.org/article/aed6452f9761422685947e7943a5b5b8
Autor:
Thais Sobanski, Amila Suraweera, Joshua T. Burgess, Iain Richard, Chee Man Cheong, Keyur Dave, Maddison Rose, Mark N. Adams, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Glucose metabolism and DNA repair are fundamental cellular processes frequently dysregulated in cancer. In this study, we define a direct role for the glycolytic Aldolase A (ALDOA) protein in DNA double-strand break (DSB) repair. ALDOA is a
Externí odkaz:
https://doaj.org/article/a81c8e487a144595879ce2d50a37a29b
Autor:
Chenhao Gao, Carmen Amador, Rosie M. Walker, Archie Campbell, Rebecca A. Madden, Mark J. Adams, Xiaomeng Bai, Ying Liu, Miaoxin Li, Caroline Hayward, David J. Porteous, Xueyi Shen, Kathryn L. Evans, Chris S. Haley, Andrew M. McIntosh, Pau Navarro, Yanni Zeng
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract Background The variation in the rate at which humans age may be rooted in early events acting through the genomic regions that are influenced by such events and subsequently are related to health phenotypes in later life. The parent-of-origi
Externí odkaz:
https://doaj.org/article/b78a5a466ff14b5192c67c87ae1821d6
Autor:
Sugandha Bhatia, Jennifer H Gunter, Joshua T Burgess, Mark N Adams, Kenneth O'Byrne, Erik W Thompson, Pascal HG Duijf
Publikováno v:
Translational Oncology, Vol 37, Iss , Pp 101760- (2023)
Epithelial-mesenchymal plasticity (EMP) is a hallmark of cancer. By enabling cells to shift between different morphological and functional states, EMP promotes invasion, metastasis and therapy resistance. We report that near-diploid non-cancerous hum
Externí odkaz:
https://doaj.org/article/dffc9a60d0e54a2aa2cf2618bde6ad7a