Zobrazeno 1 - 10
of 741
pro vyhledávání: '"Mark A Tarnopolsky"'
Autor:
Mats I Nilsson, Jacqueline M Bourgeois, Joshua P Nederveen, Marlon R Leite, Bart P Hettinga, Adam L Bujak, Linda May, Ethan Lin, Michael Crozier, Daniel R Rusiecki, Chris Moffatt, Paul Azzopardi, Jacob Young, Yifan Yang, Jenny Nguyen, Ethan Adler, Lucy Lan, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233401 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0210863.].
Externí odkaz:
https://doaj.org/article/c4c3400a1e45460792a00141e0b874bf
Autor:
Mats I Nilsson, Jacqueline M Bourgeois, Joshua P Nederveen, Marlon R Leite, Bart P Hettinga, Adam L Bujak, Linda May, Ethan Lin, Michael Crozier, Daniel R Rusiecki, Chris Moffatt, Paul Azzopardi, Jacob Young, Yifan Yang, Jenny Nguyen, Ethan Adler, Lucy Lan, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210863 (2019)
Biological aging is associated with progressive damage accumulation, loss of organ reserves, and systemic inflammation ('inflammaging'), which predispose for a wide spectrum of chronic diseases, including several types of cancer. In contrast, aerobic
Externí odkaz:
https://doaj.org/article/8b86f06b993f4187b915b9a8dc50300d
Autor:
Andrew T Chen, Lauren Brady, Dennis E Bulman, Arun N E Sundaram, Amadeo R Rodriguez, Edward Margolin, John S Waye, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225656 (2019)
PurposeTo assess the clinical utility of next-generation sequencing (NGS) for the diagnosis of patients with optic atrophy (OA).DesignRetrospective cohort study.Methods97 patients were referred to the McMaster University Medical Center (Hamilton, Ont
Externí odkaz:
https://doaj.org/article/4f4c312ec7cb41b18ade0839bd115873
Autor:
Mats I Nilsson, Mark A Tarnopolsky
Publikováno v:
Biology, Vol 8, Iss 2, p 40 (2019)
Mitochondria orchestrate the life and death of most eukaryotic cells by virtue of their ability to supply adenosine triphosphate from aerobic respiration for growth, development, and maintenance of the ‘physiologic reserve’. Although their double
Externí odkaz:
https://doaj.org/article/43fa25679eda4d05987cbb8daee72510
Autor:
Jenna B Gillen, Brian J Martin, Martin J MacInnis, Lauren E Skelly, Mark A Tarnopolsky, Martin J Gibala
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154075 (2016)
AIMS:We investigated whether sprint interval training (SIT) was a time-efficient exercise strategy to improve insulin sensitivity and other indices of cardiometabolic health to the same extent as traditional moderate-intensity continuous training (MI
Externí odkaz:
https://doaj.org/article/0d8f38860885479c87ee1ba61460002b
Autor:
Mats I Nilsson, Lauren G Macneil, Yu Kitaoka, Fatimah Alqarni, Rahul Suri, Mahmood Akhtar, Maria E Haikalis, Pavneet Dhaliwal, Munim Saeed, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102549 (2014)
Calpain-3 deficiency causes oxidative and nitrosative stress-induced damage in skeletal muscle of LGMD2A patients, but mitochondrial respiratory chain function and anti-oxidant levels have not been systematically assessed in this clinical population
Externí odkaz:
https://doaj.org/article/810d288f49a44d6a989a6eb800eef869
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109189 (2014)
Concurrent exercise combines different modes of exercise (e.g., aerobic and resistance) into one training protocol, providing stimuli meant to increase muscle strength, aerobic capacity and mass. As disuse is associated with decrements in strength, a
Externí odkaz:
https://doaj.org/article/0f8dfd96189749f88c30a32523269cec
Autor:
Jenna B Gillen, Michael E Percival, Lauren E Skelly, Brian J Martin, Rachel B Tan, Mark A Tarnopolsky, Martin J Gibala
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111489 (2014)
We investigated whether a training protocol that involved 3 min of intense intermittent exercise per week--within a total training time commitment of 30 min including warm up and cool down--could increase skeletal muscle oxidative capacity and marker
Externí odkaz:
https://doaj.org/article/b7e48abaeeb849f088e9b841cd9d370d
Autor:
Justin D Crane, Arkan Abadi, Bart P Hettinga, Daniel I Ogborn, Lauren G MacNeil, Gregory R Steinberg, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81879 (2013)
Mitochondrial oxidative stress is a complex phenomenon that is inherently tied to energy provision and is implicated in many metabolic disorders. Exercise training increases mitochondrial oxidative capacity in skeletal muscle yet it remains unclear i
Externí odkaz:
https://doaj.org/article/361d3eb9c47642e8924a6b9375396e30
Autor:
Imtiaz A Samjoo, Adeel Safdar, Mazen J Hamadeh, Alexander W Glover, Nicholas J Mocellin, Jose Santana, Jonathan P Little, Gregory R Steinberg, Sandeep Raha, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66322 (2013)
Lower skeletal muscle mitochondrial oxidative phosphorylation capacity (OXPHOS) and intramyocellular lipid (IMCL) accumulation have been implicated in the etiology of insulin resistance (IR) in obesity. The purpose of this study was to examine the im
Externí odkaz:
https://doaj.org/article/2a58bb6df3934c3fb22e53f826ea662a