Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Mark A T Blaskovich"'
Autor:
Samuel Kraus, Megan L Fletcher, Urszula Łapińska, Krina Chawla, Evan Baker, Erin L Attrill, Paul O'Neill, Audrey Farbos, Aaron Jeffries, Edouard E Galyov, Sunee Korbsrisate, Kay B Barnes, Sarah V Harding, Krasimira Tsaneva-Atanasova, Mark A T Blaskovich, Stefano Pagliara
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012361 (2024)
The interactions between a virus and its host vary in space and time and are affected by the presence of molecules that alter the physiology of either the host or the virus. Determining the molecular mechanisms at the basis of these interactions is p
Externí odkaz:
https://doaj.org/article/b6c3583e1ed849f4a0d265bd93bc466b
Autor:
Serena Bettoni, Karolina Maziarz, M Rhia L Stone, Mark A T Blaskovich, Jan Potempa, Maria Luiza Bazzo, Magnus Unemo, Sanjay Ram, Anna M. Blom
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotic
Externí odkaz:
https://doaj.org/article/03c7d679788e4513a54e468ecd9f8a56
Autor:
Yaoqin Hong, Jilong Qin, Anthony D. Verderosa, Sophia Hawas, Bing Zhang, Mark A. T. Blaskovich, John E. Cronan, Makrina Totsika
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Antibiotic resistance is one of the most prominent threats to modern medicine. In the latest World Health Organization list of bacterial pathogens that urgently require new antibiotics, 9 out of 12 are Gram-negative, with four being of “cr
Externí odkaz:
https://doaj.org/article/b9f5f0e1e2d3478f8b00822452660aa7
Autor:
Maytham Hussein, Rafah Allobawi, Irini Levou, Mark A. T. Blaskovich, Gauri G. Rao, Jian Li, Tony Velkov
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 786 (2022)
Polymyxins have resurged as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As reports of polymyxin resistance in A. baumannii with monotherapy have become increasingly common, combination therapy is usually the only
Externí odkaz:
https://doaj.org/article/64ac89b305bd40c3acb3ceb479be1c7d
Autor:
Mariusz Skwarczynski, Sahra Bashiri, Ye Yuan, Zyta M. Ziora, Osama Nabil, Keita Masuda, Mattaka Khongkow, Natchanon Rimsueb, Horacio Cabral, Uracha Ruktanonchai, Mark A. T. Blaskovich, Istvan Toth
Publikováno v:
Antibiotics, Vol 11, Iss 3, p 412 (2022)
The development of effective treatments against infectious diseases is an extensive and ongoing process due to the rapid adaptation of bacteria to antibiotic-based therapies. However, appropriately designed activity enhancers, including antibiotic de
Externí odkaz:
https://doaj.org/article/fbb24d51e5e641b3b90e7b1237331fbc
Autor:
Jennifer R. Baker, Peter J. Cossar, Mark A. T. Blaskovich, Alysha G. Elliott, Johannes Zuegg, Matthew A. Cooper, Peter J. Lewis, Adam McCluskey
Publikováno v:
Molecules, Vol 27, Iss 7, p 2050 (2022)
Five focused compound libraries (forty-nine compounds), based on prior studies in our laboratory were synthesized and screened for antibiotic and anti-fungal activity against S. aureus, E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, C. albicans
Externí odkaz:
https://doaj.org/article/ab332b6912d442a1883d30a187601a8c
Publikováno v:
RSC Medicinal Chemistry. 14:800-822
Antimicrobial resistance (AMR) is a global threat to society due to the increasing emergence of multi-drug resistant bacteria that are not susceptible to our last line of defence antibiotics: new approaches are needed to fight back.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6577dc5c6b41f6dfb0adb831ce1d8570
https://doi.org/10.1039/d2md00465h
https://doi.org/10.1039/d2md00465h
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1358-1362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::196cae75ec92e2c04b0f52a73aeb5b75
https://doi.org/10.1021/acsmedchemlett.2c00185
https://doi.org/10.1021/acsmedchemlett.2c00185
Autor:
Alan H. Zhang, Ingrid A. Edwards, Biswa P. Mishra, Gagan Sharma, Michael D. Healy, Alysha G. Elliott, Mark A. T. Blaskovich, Matthew A. Cooper, Brett M. Collins, Xinying Jia, Mehdi Mobli
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
The lipid composition of the cellular membrane plays an important role in a number of biological processes including the binding of membrane-active peptides. Characterization of membrane binding remains challenging, due to the technical limitations a
Externí odkaz:
https://doaj.org/article/47578dbefa25402bbf476b8f10c29f60
Autor:
Bing Zhang, Wanida Phetsang, M. Rhia L. Stone, Sanjaya Kc, Mark S. Butler, Matthew A. Cooper, Alysha G. Elliott, Urszula Łapińska, Margaritis Voliotis, Krasimira Tsaneva-Atanasova, Stefano Pagliara, Mark A. T. Blaskovich
Publikováno v:
Communications Biology. 6
Antimicrobial resistance is an urgent threat to human health, and new antibacterial drugs are desperately needed, as are research tools to aid in their discovery and development. Vancomycin is a glycopeptide antibiotic that is widely used for the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3449c5760e322e6015e02e91ebee72
https://doi.org/10.1038/s42003-023-04745-x
https://doi.org/10.1038/s42003-023-04745-x