Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mark A Rould"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85763 (2014)
T. gondii uses substrate-dependent gliding motility to invade cells of its hosts, egress from these cells at the end of its lytic cycle and disseminate through the host organism during infection. The ability of the parasite to move is therefore criti
Externí odkaz:
https://doaj.org/article/676b942bebf444babb2045a447c54d99
Publikováno v:
Nucleic Acids Research
Rad51 protein promotes homologous recombination in eukaryotes. Recombination activities are activated by Rad51 filament assembly on ssDNA. Previous studies of yeast Rad51 showed that His352 occupies an important position at the filament interface, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f65756892fee7b9c11047ec0168f20
http://europepmc.org/articles/PMC2919713
http://europepmc.org/articles/PMC2919713
Publikováno v:
Journal of Biological Chemistry. 281:31909-31919
Actin filament growth and disassembly, as well as affinity for actin-binding proteins, is mediated by the nucleotide-bound state of the component actin monomers. The structural differences between ATP-actin and ADP-actin, however, remain controversia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e797a4c300b9dffe00990acdcbb5151f
https://doi.org/10.1016/s0021-9258(19)84105-4
https://doi.org/10.1016/s0021-9258(19)84105-4
Autor:
Peter J. Halbrooks, Stephen J. Everse, Clemens Vonrhein, Jeremy L. Wally, Anne B. Mason, Susan K. Buchanan, Mark A. Rould
Publikováno v:
Journal of Biological Chemistry. 281:24934-24944
Serum transferrin reversibly binds iron in each of two lobes and delivers it to cells by a receptor-mediated, pH-dependent process. The binding and release of iron result in a large conformational change in which two subdomains in each lobe close or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df64bb7d14709ccb679f3aff1aa00f96
https://doi.org/10.1074/jbc.m604592200
https://doi.org/10.1074/jbc.m604592200
Publikováno v:
Nature. 399:708-712
The anticancer activity of cis-diamminedichloroplatinum(II) (cisplatin) arises from its ability to damage DNA, with the major adducts formed being intrastrand d(GpG) and d(ApG) crosslinks. These crosslinks bend and unwind the duplex, and the altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d69051bf7fc79e90263a342c714900
https://doi.org/10.1038/21460
https://doi.org/10.1038/21460
Publikováno v:
Journal of Molecular Biology. 284:351-361
We report the 2.2 A resolution structure of the Drosophila engrailed homeodomain bound to its optimal DNA site. The original 2.8 A resolution structure of this complex provided the first detailed three-dimensional view of how homeodomains recognize D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122dbe0b00022904896cd07bc3d03b46
https://doi.org/10.1006/jmbi.1998.2147
https://doi.org/10.1006/jmbi.1998.2147
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 62:1013-1015
Bacteriophage T4 UvsY protein is considered to be the prototype of recombination mediator proteins, a class of proteins which assist in the loading of recombinases onto DNA. Wild-type and Se-substituted UvsY protein have been expressed and purified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc722e651d63302955ccc482ca49e684
https://doi.org/10.1107/s1744309106036074
https://doi.org/10.1107/s1744309106036074