Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mark A Ozog"'
Autor:
Funda Meric-Bernstam, Muralidhar Beeram, Erika Hamilton, Do-Youn Oh, Diana L Hanna, Yoon-Koo Kang, Elena Elimova, Jorge Chaves, Rachel Goodwin, Jeeyun Lee, Lisle Nabell, Sun Young Rha, Jose Mayordomo, Anthony El-Khoueiry, Shubham Pant, Kanwal Raghav, Jin Won Kim, Amita Patnaik, Todd Gray, Rupert Davies, Mark A Ozog, Joseph Woolery, Keun-Wook Lee
Publikováno v:
The Lancet Oncology. 23:1558-1570
HER2-targeted therapies have substantially improved outcomes for patients with HER2-positive breast and gastric or gastro-oesophageal junction cancers. Several other cancers exhibit HER2 expression or amplification, suggesting that HER2-targeted agen
Autor:
Jeffrey Wilken, Anthony Traboulsee, Flavia Nelson, Carolina Ionete, Shannon Kolind, Timothy Fratto, Robert Kane, Roopali Gandhi, Andreea M. Rawlings, Nora Roesch, Mark A. Ozog, John DeLuca
Publikováno v:
Multiple Sclerosis and Related Disorders. 73:104677
Publikováno v:
Journal of Biological Chemistry. 285:31107-31119
Increases in extracellular potassium concentration ([K(+)](o)), which can occur during neuronal activity and under pathological conditions such as ischemia, lead to a variety of potentially detrimental effects on neuronal function. Although astrocyte
Publikováno v:
Journal of Neuroscience. 29:8946-8959
The ubiquitously expressed Na(+)/H(+) exchanger NHE1 plays an important role in regulating polarized membrane protrusion and directional motility in non-neuronal cells. Using NGF-differentiated PC12 cells and murine neocortical neurons in vitro, we n
Publikováno v:
Journal of Biological Chemistry. 283:6546-6560
Attempts to promote neuronal survival and repair with ciliary neurotrophic factor (CNTF) have met with limited success. The variability of results obtained with CNTF may, in part, reflect the fact that some of the biological actions of the cytokine a
Publikováno v:
Journal of Biological Chemistry. 279:36943-36950
Many tumor cells exhibit aberrant gap junctional intercellular communication, which can be restored by transfection with connexin genes. We have previously discovered that overexpression of connexin43 (Cx43) in C6 glioma cells not only reduces prolif
Publikováno v:
Journal of Neurochemistry. 71:1429-1435
Rilmenidine, a ligand for imidazoline and α 2 -adrenergic receptors, is neuroprotective following focal cerebral ischemia. We investigated the effects of rilmenidine on cytosolic free Ca 2+ concentration ([Ca 2+ ] i ) in rat astrocytes. Rilmenidine
Publikováno v:
Biochemistry and Cell Biology. 79:387-398
Recent advances in genetic technology have provided a new platform on which the simultaneous analysis of a large number of genes is possible in a rapid and efficient fashion. To assess the differential expression of human genes during neuronal differ
Publikováno v:
Cell Communication & Adhesion. 8:325-328
Glial-neuronal interactions have been implicated in both normal information processing and neuroprotection. One pathway of cellular interactions involves gap junctional intercellular communication (GJIC). In astrocytes, gap junctions are composed pri
Publikováno v:
The Journal of comparative neurology. 504(3)
During embryonic development, young neurons migrate from the ventricular zone to the cortical plate of the cerebral cortex. Disturbances in this neuronal migration have been associated with numerous diseases such as mental retardation, double cortex,