Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark A McEvoy"'
Autor:
William R Reay, Sahar I El Shair, Michael P Geaghan, Carlos Riveros, Elizabeth G Holliday, Mark A McEvoy, Stephen Hancock, Roseanne Peel, Rodney J Scott, John R Attia, Murray J Cairns
Publikováno v:
eLife, Vol 10 (2021)
Measures of lung function are heritable, and thus, we sought to utilise genetics to propose drug-repurposing candidates that could improve respiratory outcomes. Lung function measures were found to be genetically correlated with seven druggable bioch
Externí odkaz:
https://doaj.org/article/16e00623321540a6a30d5172abea081f
Autor:
Paul S de Vries, Maria Sabater-Lleal, Daniel I Chasman, Stella Trompet, Tarunveer S Ahluwalia, Alexander Teumer, Marcus E Kleber, Ming-Huei Chen, Jie Jin Wang, John R Attia, Riccardo E Marioni, Maristella Steri, Lu-Chen Weng, Rene Pool, Vera Grossmann, Jennifer A Brody, Cristina Venturini, Toshiko Tanaka, Lynda M Rose, Christopher Oldmeadow, Johanna Mazur, Saonli Basu, Mattias Frånberg, Qiong Yang, Symen Ligthart, Jouke J Hottenga, Ann Rumley, Antonella Mulas, Anton J M de Craen, Anne Grotevendt, Kent D Taylor, Graciela E Delgado, Annette Kifley, Lorna M Lopez, Tina L Berentzen, Massimo Mangino, Stefania Bandinelli, Alanna C Morrison, Anders Hamsten, Geoffrey Tofler, Moniek P M de Maat, Harmen H M Draisma, Gordon D Lowe, Magdalena Zoledziewska, Naveed Sattar, Karl J Lackner, Uwe Völker, Barbara McKnight, Jie Huang, Elizabeth G Holliday, Mark A McEvoy, John M Starr, Pirro G Hysi, Dena G Hernandez, Weihua Guan, Fernando Rivadeneira, Wendy L McArdle, P Eline Slagboom, Tanja Zeller, Bruce M Psaty, André G Uitterlinden, Eco J C de Geus, David J Stott, Harald Binder, Albert Hofman, Oscar H Franco, Jerome I Rotter, Luigi Ferrucci, Tim D Spector, Ian J Deary, Winfried März, Andreas Greinacher, Philipp S Wild, Francesco Cucca, Dorret I Boomsma, Hugh Watkins, Weihong Tang, Paul M Ridker, Jan W Jukema, Rodney J Scott, Paul Mitchell, Torben Hansen, Christopher J O'Donnell, Nicholas L Smith, David P Strachan, Abbas Dehghan
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0167742 (2017)
An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associa
Externí odkaz:
https://doaj.org/article/747b3e99f9484bed947ca09451fdbbf2
Autor:
Mark A McEvoy, Peter W Schofield, Wayne T Smith, Kingsley Agho, Arduino A Mangoni, Roy L Soiza, Roseanne Peel, Stephen J Hancock, Ciriaco Carru, Angelo Zinellu, John R Attia
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e58390 (2013)
RationaleMethylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in animal models of lung disease but have not previously been examined for their association with spirometric measures of lung function in humans.Objec
Externí odkaz:
https://doaj.org/article/4c60f233f3d947389f1f2663baccfdbd
Autor:
Pui Fung Li, Mark A. McEvoy, Sharmaine McKiernan, Peter W. Schofield, Lesley K. MacDonald-Wicks, Amanda J. Patterson
Publikováno v:
Nutrients, Vol 13, Iss 3, p 909 (2021)
There is a lack of evidence to determine if diet quality is associated with cognitive performance in older adults. Therefore, the aim of this study was to examine whether diet quality is associated with cognitive performance among older adults. A cro
Externí odkaz:
https://doaj.org/article/bf0e8853c3fa428ba646e5cf99a5a2b4
Autor:
Riccardo E. Marioni, Christopher J. O'Donnell, Oscar H. Franco, Johan G. Eriksson, Francesco Cucca, Jonathan Marten, Alexander P. Reiner, Tim D. Spector, Philipp S. Wild, Paul Mitchell, Wolfgang Koenig, Barbara McKnight, J. Wouter Jukema, Alan F. Wright, Maria Sabater-Lleal, Charles Kooperberg, Albert Hofman, Talin Haritunians, Martina Müller-Nurasyid, Jie Huang, Jie Yao, Marcus E. Kleber, Pau Navarro, Nicholas L. Smith, Jennifer E. Huffman, Lynda M. Rose, Russell P. Tracy, Antti-Pekka Sarin, Stefania Bandinelli, Ian J. Deary, Aarno Palotie, Saonli Basu, Caroline Hayward, Kent D. Taylor, Winfried März, Aaron R. Folsom, Anne Grotevendt, Lawrence F. Bielak, Tarunveer S. Ahluwalia, Ming-Huei Chen, Alexander Teumer, Graciela E. Delgado, Sharon L.R. Kardia, Peter K. Joshi, Wendy L. McArdle, Toshiko Tanaka, Jing Hua Zhao, Diane M. Becker, Pierre-Emmanuel Morange, Alanna C. Morrison, Annette Kifley, Igor Rudan, Lorna M. Lopez, Kay-Tee Khaw, Nicholas J. Wareham, Eco J. C. de Geus, Mohsen Ghanbari, Jari Lahti, Tatijana Zemunik, John M. Starr, Magdalena Zoledziewska, Anuj Goel, Dena G. Hernandez, Abbas Dehghan, Ozren Polasek, Melanie Waldenberger, Helene Riess, Rodney J. Scott, Qiong Yang, Robert A. Scott, Nancy S. Jenny, Johanna Mazur, Weihong Tang, Paul M. Ridker, Torben Hansen, Anders Hamsten, James F. Wilson, Jouke J. Hottenga, Cristina Venturini, Paul L. Auer, Geoffrey H. Tofler, Pirro G. Hysi, Mark G. Mcevoy, Ann Rumley, Fernando Rivadeneira, Naveed Sattar, Ivana Kolcic, Jie Jin Wang, Jingmin Liu, Stella Trompet, Elizabeth G. Holliday, Sarah H. Wild, Maristella Steri, Uwe Völker, Tanja Zeller, Patricia A. Peyser, P. Eline Slagboom, Massimo Mangino, André G. Uitterlinden, Paul S. de Vries, Dorret I. Boomsma, Harry Campbell, Vera Grossmann, Gonneke Willemsen, Katri Räikkönen, Edoardo Fiorillo, Ares Rocanin-Arjo, Gordon D.O. Lowe, David P. Strachan, Anton J. M. de Craen, Moniek P.M. de Maat, David-Alexandre Trégouët, Jennifer A. Brody, Rehan Qayyum, Lisa R. Yanek, Luigi Ferrucci, Andreas Greinacher, Lewis C. Becker, Hugh Watkins, David J. Stott, Min A. Jhun, Tina L. Berentzen, Annette Peters, Bengt Sennblad, Daniel I. Chasman, Lihong Qi, Christopher Oldmeadow, Harald Binder, Xiuqing Guo, John Attia, Bruce M. Psaty
Publikováno v:
Human Molecular Genetics, 25(2), 358-370
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 25 (2), pp.358-370. ⟨10.1093/hmg/ddv454⟩
Human Molecular Genetics, 25(2), 358-370. Oxford University Press
de Vries, P S, Chasman, D I, Sabater-Lleal, M, Chen, M H, Huffman, J E, Steri, M, Tang, W, Teumer, A, Marioni, R E, Grossmann, V, Hottenga, J J, Willemsen, G, de Geus, E J C, Boomsma, D I, Cucca, F, Tracy, R, Watkins, H, Reiner, A P, Folsom, A R, Ridker, P M, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2016, ' A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration ', Human Molecular Genetics, vol. 25, no. 2, pp. 358-370 . https://doi.org/10.1093/hmg/ddv454
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 25 (2), pp.358-370. ⟨10.1093/hmg/ddv454⟩
Human Molecular Genetics, 25(2), 358-370. Oxford University Press
de Vries, P S, Chasman, D I, Sabater-Lleal, M, Chen, M H, Huffman, J E, Steri, M, Tang, W, Teumer, A, Marioni, R E, Grossmann, V, Hottenga, J J, Willemsen, G, de Geus, E J C, Boomsma, D I, Cucca, F, Tracy, R, Watkins, H, Reiner, A P, Folsom, A R, Ridker, P M, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2016, ' A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration ', Human Molecular Genetics, vol. 25, no. 2, pp. 358-370 . https://doi.org/10.1093/hmg/ddv454
Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better covera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd6ce9c52e253d0a5d0162a8a3295cc
http://hdl.handle.net/1887/112436
http://hdl.handle.net/1887/112436
Autor:
Cristian Pattaro, Alexander Teumer, Mathias Gorski, Audrey Y. Chu, Man Li, Vladan Mijatovic, Maija Garnaas, Adrienne Tin, Rossella Sorice, Yong Li, Daniel Taliun, Matthias Olden, Meredith Foster, Qiong Yang, Ming-Huei Chen, Tune H. Pers, Andrew D. Johnson, Yi-An Ko, Christian Fuchsberger, Bamidele Tayo, Michael Nalls, Mary F. Feitosa, Aaron Isaacs, Abbas Dehghan, Pio d’Adamo, Adebowale Adeyemo, Aida Karina Dieffenbach, Alan B. Zonderman, Ilja M. Nolte, Peter J. van der Most, Alan F. Wright, Alan R. Shuldiner, Alanna C. Morrison, Albert Hofman, Albert V. Smith, Albert W. Dreisbach, Andre Franke, Andre G. Uitterlinden, Andres Metspalu, Anke Tonjes, Antonio Lupo, Antonietta Robino, Åsa Johansson, Ayse Demirkan, Barbara Kollerits, Barry I. Freedman, Belen Ponte, Ben A. Oostra, Bernhard Paulweber, Bernhard K. Krämer, Braxton D. Mitchell, Brendan M. Buckley, Carmen A. Peralta, Caroline Hayward, Catherine Helmer, Charles N. Rotimi, Christian M. Shaffer, Christian Müller, Cinzia Sala, Cornelia M. van Duijn, Aude Saint-Pierre, Daniel Ackermann, Daniel Shriner, Daniela Ruggiero, Daniela Toniolo, Yingchang Lu, Daniele Cusi, Darina Czamara, David Ellinghaus, David S. Siscovick, Douglas Ruderfer, Christian Gieger, Harald Grallert, Elena Rochtchina, Elizabeth J. Atkinson, Elizabeth G. Holliday, Eric Boerwinkle, Erika Salvi, Erwin P. Bottinger, Federico Murgia, Fernando Rivadeneira, Florian Ernst, Florian Kronenberg, Frank B. Hu, Gerjan J. Navis, Gary C. Curhan, George B. Ehret, Georg Homuth, Stefan Coassin, Gian-Andri Thun, Giorgio Pistis, Giovanni Gambaro, Giovanni Malerba, Grant W. Montgomery, Gudny Eiriksdottir, Gunnar Jacobs, Guo Li, H-Erich Wichmann, Harry Campbell, Helena Schmidt, Henri Wallaschofski, Henry Völzke, Hermann Brenner, Heyo K. Kroemer, Holly Kramer, Honghuang Lin, I. Mateo Leach, Ian Ford, Idris Guessous, Igor Rudan, Inga Prokopenko, Ingrid Borecki, Iris M. Heid, Ivana Kolcic, Ivana Persico, J. Wouter Jukema, James F. Wilson, Janine F. Felix, Jasmin Divers, Jean-Charles Lambert, Jeanette M. Stafford, Jean-Michel Gaspoz, Jennifer A. Smith, Jessica D. Faul, Jie Jin Wang, Jingzhong Ding, Joel N. Hirschhorn, John Attia, John B. Whitfield, John Chalmers, Jorma Viikari, Josef Coresh, Joshua C. Denny, Juha Karjalainen, Jyotika K. Fernandes, Karlhans Endlich, Katja Butterbach, Keith L. Keene, Kurt Lohman, Laura Portas, Lenore J. Launer, Leo-Pekka Lyytikäinen, Loic Yengo, Lude Franke, Luigi Ferrucci, Lynda M. Rose, Lyudmyla Kedenko, Madhumathi Rao, Maksim Struchalin, Marcus E. Kleber, Margherita Cavalieri, Margot Haun, Marilyn C. Cornelis, Marina Ciullo, Mario Pirastu, Mariza de Andrade, Mark A. McEvoy, Mark Woodward, Martin Adam, Massimiliano Cocca, Matthias Nauck, Medea Imboden, Melanie Waldenberger, Menno Pruijm, Marie Metzger, Michael Stumvoll, Michele K. Evans, Michele M. Sale, Mika Kähönen, Mladen Boban, Murielle Bochud, Myriam Rheinberger, Niek Verweij, Nabila Bouatia-Naji, Nicholas G. Martin, Nick Hastie, Nicole Probst-Hensch, Nicole Soranzo, Olivier Devuyst, Olli Raitakari, Omri Gottesman, Oscar H. Franco, Ozren Polasek, Paolo Gasparini, Patricia B. Munroe, Paul M. Ridker, Paul Mitchell, Paul Muntner, Christa Meisinger, Johannes H. Smit, ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Peter Kovacs, Philipp S. Wild, Philippe Froguel, Rainer Rettig, Reedik Mägi, Reiner Biffar, Reinhold Schmidt, Rita P. S. Middelberg, Robert J. Carroll, Brenda W. Penninx, Rodney J. Scott, Ronit Katz, Sanaz Sedaghat, Sarah H. Wild, Sharon L. R. Kardia, Sheila Ulivi, Shih-Jen Hwang, Stefan Enroth, Stefan Kloiber, Stella Trompet, Benedicte Stengel, Stephen J. Hancock, Stephen T. Turner, Sylvia E. Rosas, Sylvia Stracke, Tamara B. Harris, Tanja Zeller, Tatijana Zemunik, Terho Lehtimäki, Thomas Illig, Thor Aspelund, Tiit Nikopensius, Tonu Esko, Toshiko Tanaka, Ulf Gyllensten, Uwe Völker, Valur Emilsson, Veronique Vitart, Ville Aalto, Vilmundur Gudnason, Vincent Chouraki, Wei-Min Chen, Wilmar Igl, Winfried März, Wolfgang Koenig, Wolfgang Lieb, Ruth J. F. Loos, Yongmei Liu, Harold Snieder, Peter P. Pramstaller, Afshin Parsa, Jeffrey R. O’Connell, Katalin Susztak, Pavel Hamet, Johanne Tremblay, Ian H. de Boer, Carsten A. Böger, Wolfram Goessling, Daniel I. Chasman, Anna Köttgen, W. H. Linda Kao, Caroline S. Fox
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode
Externí odkaz:
https://doaj.org/article/5d9d63e116c24c36a1c1be4822c2160b
Autor:
Jacklyn K. Jackson, Amanda J. Patterson, Lesley K. MacDonald-Wicks, Peta M. Forder, Lauren C. Blekkenhorst, Catherine P. Bondonno, Jonathan M. Hodgson, Natalie C. Ward, Carl Holder, Christopher Oldmeadow, Julie E. Byles, Mark A. McEvoy
Publikováno v:
Nutrients, Vol 11, Iss 2, p 240 (2019)
Nitric oxide (NO) facilitates anti-atherosclerotic effects. Vegetables are a major source of dietary nitrate. Experimental data indicates that dietary nitrate can significantly reduce major risk factors for atherosclerosis and subsequent cardiovascul
Externí odkaz:
https://doaj.org/article/94f868bd5e4145f29cbe399110b8d599
Autor:
Jacklyn K. Jackson, Amanda J. Patterson, Lesley K. MacDonald-Wicks, Catherine P. Bondonno, Lauren C. Blekkenhorst, Natalie C. Ward, Jonathan M. Hodgson, Julie E. Byles, Mark A. McEvoy
Publikováno v:
Nutrients, Vol 10, Iss 8, p 1005 (2018)
Dietary nitrate is increasingly linked to a variety of beneficial health outcomes. Our purpose was to estimate dietary nitrate consumption and identify key dietary changes which have occurred over time within a representative sample of Australian wom
Externí odkaz:
https://doaj.org/article/8cbbc1f14a1342aa8a70eed12b743edc
Autor:
Angela J. Reeves, Mark A. McEvoy, Lesley K. MacDonald-Wicks, Daniel Barker, John Attia, Allison M. Hodge, Amanda J. Patterson
Publikováno v:
Nutrients, Vol 9, Iss 5, p 515 (2017)
Total iron intake is not strongly associated with iron stores, but haem iron intake may be more predictive. Haem iron is not available in most nutrient databases, so experimentally determined haem contents were applied to an Australian Food Frequency
Externí odkaz:
https://doaj.org/article/9a67c8cb9fd64d8a83464d2feb4cc76e