Výsledky vyhledávání - "Mark A Kirkland"

Akademický článek

M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts.

Autor: Jason M Hodge, Fiona M Collier, Nathan J Pavlos, Mark A Kirkland, Geoffrey C Nicholson

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21462 (2011)

Macrophage-CSF (M-CSF) is critical for osteoclast (OC) differentiation and is reported to enhance mature OC survival and motility. However, its role in the regulation of bone resorption, the main function of OCs, has not been well characterised. To a

Externí odkaz: https://doaj.org/article/5e35af53f8344c7fb260abc9b243bfd3

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Akademický článek

Enhanced Ex Vivo Expansion of Human Hematopoietic Progenitors on Native and Spin Coated Acellular Matrices Prepared from Bone Marrow Stromal Cells

Autor: Samiksha Wasnik, Suma Kantipudi, Mark A. Kirkland, Gopal Pande

Publikováno v: Stem Cells International, Vol 2016 (2016)

The extracellular microenvironment in bone marrow (BM) is known to regulate the growth and differentiation of hematopoietic stem and progenitor cells (HSPC). We have developed cell-free matrices from a BM stromal cell line (HS-5), which can be used a

Externí odkaz: https://doaj.org/article/f1517198e8464b008458651a5f6d582a

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Thiol surface functionalization via continuous phase plasma polymerization of allyl mercaptan, with subsequent maleimide-linked conjugation of collagen

Autor: George Kiroff, Wayne A. Morrison, Gil D. Stynes, Mark A. Kirkland, Thomas R. Gengenbach

Publikováno v: Journal of Biomedical Materials Research Part A. 105:1940-1948

Thiol groups can undergo a large variety of chemical reactions and are used in solution phase to conjugate many bioactive molecules. Previous research on solid substrates with continuous phase glow discharge polymerization of thiol-containing monomer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64bca9084636a97b70a40e229ba1d4bb
https://doi.org/10.1002/jbm.a.36064

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Surface-bound collagen 4 is significantly more stable than collagen 1

Autor: Wayne A. Morrison, Richard S. Page, George Kiroff, Gil D. Stynes, Mark A. Kirkland

Publikováno v: Journal of Biomedical Materials Research Part A. 105:1364-1373

Collagen 1 (C1) is commonly used to improve biological responses to implant surfaces. Here, the stability of C1 was compared with collagen 4 (C4) on a mixed macrodiol polyurethane, both adsorbed and covalently bound via acetaldehyde glow discharge po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ff554c67c39bca59d6dc769c19b682b
https://doi.org/10.1002/jbm.a.36019

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Metal ion type significantly affects the morphology but not the activity of lipase–metal–phosphate nanoflowers

Autor: Munish Puri, Mark A. Kirkland, W. Cong, Nishat Sharma, Srikanth Mateti, Marzieh Parhizkar, Alessandra Sutti

Publikováno v: RSC Advances. 7:25437-25443

Enzyme–metal-ion–phosphate nanoflowers are high-surface area materials which are known to show higher activity than the constituting protein. Although the synthesis of hybrid nanoflowers has been demonstrated with a variety of proteins and reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ac7135bcbcb4b3891416c1645daa5ef
https://doi.org/10.1039/c7ra00302a

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Toward a skin-material interface with vacuum-integrated capped macroporous scaffolds

Autor: Mark A. Kirkland, Wayne A. Morrison, George Kiroff, Gil D. Stynes, Richard S. Page

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:1307-1318

Avulsion, epidermal marsupialization, and infection cause failure at the skin-material interface. A robust interface would permit implantable robotics, prosthetics, and other medical devices; reconstruction of surgical defects, and long-term access t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eea66f7ff51e735d997996f7cdd170ab
https://doi.org/10.1002/jbm.b.33649

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EnhancedEx VivoExpansion of Human Hematopoietic Progenitors on Native and Spin Coated Acellular Matrices Prepared from Bone Marrow Stromal Cells

Autor: Gopal Pande, Mark A. Kirkland, Samiksha Wasnik, Suma Kantipudi

Publikováno v: Stem Cells International
Stem Cells International, Vol 2016 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428b27d2171b9b7865ea3643fdb6f73b
https://doi.org/10.1155/2016/7231567

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Controlling the Effective Oxygen Tension Experienced by Cells Using a Dynamic Culture Technique for Hematopoietic Ex Vivo Expansion

Autor: Yen Pham, Jingang Li, Lakshmi Prasanna Nekkanti, Graham Jenkin, Amy E. Sutherland, James A. Deane, Cynthia S. Wong, Mark A. Kirkland, Abhilasha Tiwari, Courtney McDonald

Publikováno v: Current Protocols in Stem Cell Biology

Clinical hematopoietic stem/progenitor cell (HSPC) transplantation outcomes are strongly correlated with the number of cells infused. Hence, to generate sufficient HSPCs for transplantation, the best culture parameters for expansion are critical. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16af721efada2712bad8194033586f9
https://doi.org/10.1002/cpsc.42

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Feasibility of trialling cord blood stem cell treatments for cerebral palsy in Australia

Autor: Pamela Clark, Kylie E. Crompton, Dinah Reddihough, Iona Novak, Ngaire Elwood, Mark A. Kirkland

Publikováno v: Journal of Paediatrics and Child Health. 50:540-544

Aim Umbilical cord blood may have therapeutic benefit in children with cerebral palsy (CP), but further studies are required. On first appearance it seems that Australia is well placed for such a trial because we have excellence in CP research backed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::499ab077bc6144060c1675bf239b61f2
https://doi.org/10.1111/jpc.12618

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