Zobrazeno 1 - 10
of 886
pro vyhledávání: '"Mark A Jenkins"'
Autor:
Xinyuan Dong, Yu-Ru Su, Richard Barfield, Stephanie A Bien, Qianchuan He, Tabitha A Harrison, Jeroen R Huyghe, Temitope O Keku, Noralane M Lindor, Clemens Schafmayer, Andrew T Chan, Stephen B Gruber, Mark A Jenkins, Charles Kooperberg, Ulrike Peters, Li Hsu
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008947 (2020)
Genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants associated with various phenotypes, but together they explain only a fraction of heritability, suggesting many variants have yet to be discovere
Externí odkaz:
https://doaj.org/article/1d659fdda0744ff8828b2d28f5eb7ed7
Autor:
Marion Denos, Yi-Qian Sun, Ben Michael Brumpton, Yafang Li, Demetrius Albanes, Andrea Burnett-Hartman, Peter T. Campbell, Sébastien Küry, Christopher I. Li, Emily White, Jewel N. Samadder, Mark A. Jenkins, Xiao-Mei Mai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The roles of sex hormones such as estradiol, testosterone, and sex hormone-binding globulin (SHBG) in the etiology of lung and colorectal cancers in women, among the most common cancers after breast cancer, are unclear. This Mendelian random
Externí odkaz:
https://doaj.org/article/c84f598213d5405c8f1524e9194ae165
Autor:
Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim
Publikováno v:
PLoS Medicine, Vol 15, Iss 8, p e1002630 (2018)
BACKGROUND:The Australian National Bowel Cancer Screening Programme (NBCSP) was introduced in 2006. When fully implemented, the programme will invite people aged 50 to 74 to complete an immunochemical faecal occult blood test (iFOBT) every 2 years. M
Externí odkaz:
https://doaj.org/article/33deb97cf1da408a979423b53c1e24f8
Autor:
Mala Pande, Aron Joon, Abenaa M Brewster, Wei V Chen, John L Hopper, Cathy Eng, Sanjay Shete, Graham Casey, Fredrick Schumacher, Yi Lin, Tabitha A Harrison, Emily White, Habibul Ahsan, Irene L Andrulis, Alice S Whittemore, Esther M John, Aung Ko Win, Enes Makalic, Daniel F Schmidt, Miroslaw K Kapuscinski, Heather M Ochs-Balcom, Steven Gallinger, Mark A Jenkins, Polly A Newcomb, Noralane M Lindor, Ulrike Peters, Christopher I Amos, Patrick M Lynch
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196245 (2018)
BACKGROUND:Clustering of breast and colorectal cancer has been observed within some families and cannot be explained by chance or known high-risk mutations in major susceptibility genes. Potential shared genetic susceptibility between breast and colo
Externí odkaz:
https://doaj.org/article/bd291d8c4d124de39cea5462aa949b76
Autor:
Stephanie A Bien, Paul L Auer, Tabitha A Harrison, Conghui Qu, Charles M Connolly, Peyton G Greenside, Sai Chen, Sonja I Berndt, Stéphane Bézieau, Hyun M Kang, Jeroen Huyghe, Hermann Brenner, Graham Casey, Andrew T Chan, John L Hopper, Barbara L Banbury, Jenny Chang-Claude, Stephen J Chanock, Robert W Haile, Michael Hoffmeister, Christian Fuchsberger, Mark A Jenkins, Suzanne M Leal, Mathieu Lemire, Polly A Newcomb, Steven Gallinger, John D Potter, Robert E Schoen, Martha L Slattery, Joshua D Smith, Loic Le Marchand, Emily White, Brent W Zanke, Goncalo R Abeçasis, Christopher S Carlson, Ulrike Peters, Deborah A Nickerson, Anshul Kundaje, Li Hsu, GECCO and CCFR
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186518 (2017)
BACKGROUND:The evaluation of less frequent genetic variants and their effect on complex disease pose new challenges for genomic research. To investigate whether epigenetic data can be used to inform aggregate rare-variant association methods (RVAM),
Externí odkaz:
https://doaj.org/article/7f6b30b8e6f745f4b0347b6a2ebb6682
Autor:
Yiting Gong MPH, Louisa B. Flander PhD, Finlay Macrae MD, Carlene Wilson PhD, Mark A. Jenkins PhD
Publikováno v:
Cancer Control, Vol 31 (2024)
Background Colorectal cancer screening reduces colorectal cancer morbidity and mortality. Identifying the factors associated with screening participation is needed to overcome barriers to screening. While several of those factors have been identified
Externí odkaz:
https://doaj.org/article/0a6556032e254d50ba2c0308173910ea
Autor:
Mark C. Jenkins, Carolyn Parker, Andrew Jansen, Marianne Dias Papadopoulos, Matthew S. Tucker
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Eimeria maxima (APU1 and APU2) differ in virulence for chickens, due in part to the greater fecundity of the former. In a previous study, RNA-seq was used to identify a transcripts upregulated in E. maxima APU1 compared to E. maxima APU2. In this stu
Externí odkaz:
https://doaj.org/article/f4115273fb7c447caf409bcb175afe9d
Autor:
Jian Gong, Carolyn M Hutter, Polly A Newcomb, Cornelia M Ulrich, Stephanie A Bien, Peter T Campbell, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, David Duggan, Jane C Figueiredo, Steven Gallinger, Edward L Giovannucci, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Thomas J Hudson, Jihyoun Jeon, Mark A Jenkins, Jonathan Kocarnik, Sébastien Küry, Loic Le Marchand, Yi Lin, Noralane M Lindor, Reiko Nishihara, Shuji Ogino, John D Potter, Anja Rudolph, Robert E Schoen, Petra Schrotz-King, Daniela Seminara, Martha L Slattery, Stephen N Thibodeau, Mark Thornquist, Reka Toth, Robert Wallace, Emily White, Shuo Jiao, Mathieu Lemire, Li Hsu, Ulrike Peters, CCFR and GECCO
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006296 (2016)
Genome-wide association studies (GWAS) have identified many genetic susceptibility loci for colorectal cancer (CRC). However, variants in these loci explain only a small proportion of familial aggregation, and there are likely additional variants tha
Externí odkaz:
https://doaj.org/article/bc5575569e324d7fab4e4154d5310819
Autor:
Mengmeng Du, Shuo Jiao, Stephanie A Bien, Manish Gala, Goncalo Abecasis, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Thomas J Hudson, Mark A Jenkins, Sébastien Küry, Loic Le Marchand, Suzanne M Leal, Polly A Newcomb, Deborah A Nickerson, John D Potter, Robert E Schoen, Fredrick R Schumacher, Daniela Seminara, Martha L Slattery, Li Hsu, Andrew T Chan, Emily White, Sonja I Berndt, Ulrike Peters
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157521 (2016)
Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can fac
Externí odkaz:
https://doaj.org/article/f07d22c53e704733b34d5a12a9ca49fb
Autor:
Philip M. Campos, Katarzyna B. Miska, Mark C. Jenkins, Xianghe Yan, Monika Proszkowiec-Weglarz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Coccidiosis, an intestinal disease caused by Eimeria parasites, is responsible for major losses in the poultry industry by impacting chicken health. The gut microbiota is associated with health factors, such as nutrient exchange and immune s
Externí odkaz:
https://doaj.org/article/0ade0a3802cd41c8857991e2a34336d6