Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Mark A Hull"'
Autor:
Helen Marshall, Mark A Hull, David A Cairns, Andrew T Chan, Mingyang Song, Robert Jones, Peter S Hall, Catherine Moriarty, David A Drew, Wendy S Garrett, Giles J Toogood, Paul M Loadman, Andrew J Cockbain, Omer Yilmaz, Pei Loo Ow, Sharon Ruddock, Tim Brend, Alexandra F Smith, Fiona Collinson
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction There remains an unmet need for safe and cost-effective adjunctive treatment of advanced colorectal cancer (CRC). The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and has anti-inflammatory as wel
Externí odkaz:
https://doaj.org/article/6b799f009e2d4182b03f92a9a5f2e1e9
Autor:
Ramesh P Arasaradnam, Mark A Hull, John Todd, Sian Taylor-Phillips, Norman Waugh, Lazaros Andronis, Siew Wan Hee, Krishna Persaud, Steve Smith, Christopher Bradley, Rachel Constable
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Introduction Demand for colonoscopies and CT colonography (CTC) is exceeding capacity in National Health Service Trusts. In many patients colonoscopies and CTCs show no significant bowel disease (SBD). Faecal Immunochemical Testing (FIT) is being int
Externí odkaz:
https://doaj.org/article/6eab16309e2a443a9d3a9243668620e2
Autor:
Mark A Hull, Kirsty Sprange, Trish Hepburn, Wei Tan, Aisha Shafayat, Colin J Rees, Gayle Clifford, Richard F Logan, Paul M Loadman, Elizabeth A Williams, Diane Whitham, Alan A Montgomery
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 6, Iss 4 (2019)
Background: The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) and aspirin both have proof of concept for colorectal cancer (CRC) chemoprevention, aligned with an excellent safety profile. Objectives: The objectives were to determine
Externí odkaz:
https://doaj.org/article/af6edf38b81a43cabcafa96d83b3782a
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38972 (2012)
Tumour invasion and metastasis is the most common cause of death from cancer. For epithelial cells to invade surrounding tissues and metastasise, an epithelial-mesenchymal transition (EMT) is required. We have demonstrated that FGFR1 expression is in
Externí odkaz:
https://doaj.org/article/fcd62f245cff432cb357dcb45532ad61
Publikováno v:
Lifestyle Genomics, Pp 1-4 (2022)
Background: Arachidonic acid (ARA) is associated with colorectal cancer (CRC), a major public health concern. However, it is uncertain if ARA contributes to the development of colorectal polyps which are pre-malignant precursors of CRC. Objective: Th
Externí odkaz:
https://doaj.org/article/9ec69c4047a04a6e928b55a6f6f98cdb
Autor:
Rebecca J, Birch, Nicholas, Burr, Venkataraman, Subramanian, Jim P, Tiernan, Mark A, Hull, Paul, Finan, Azmina, Rose, Matthew, Rutter, Roland, Valori, Amy, Downing, Eva J A, Morris
Publikováno v:
American Journal of Gastroenterology. 117:1858-1870
Introduction: Patients with inflammatory bowel diseases (IBDs) of the colon are at an increased risk of colorectal cancer (CRC). This study investigates the epidemiology of IBD-CRC and its outcomes. Methods: Using population data from the English Nat
Autor:
James S. Hampton, Sara Koo, Christina Dobson, Christopher J. Stewart, Laura J. Neilson, Kyle Montague, Suparna Mitra, John Whelpton, Caroline Addison, Phil Kelly, Stephen Rushton, Mark A. Hull, Linda Sharp, Colin J. Rees
Publikováno v:
Colorectal Disease. 24:1216-1226
Introduction\ud The COLO-COHORT study aims to produce a multi-factorial risk prediction model for colorectal neoplasia that will be able to be used to target colonoscopy to those at greatest risk of colorectal neoplasia, ensuring that people are not
Publikováno v:
Gut. 71:822-837
Data from experimental studies have demonstrated that marine omega-3 polyunsaturated fatty acids (O3FAs) have anti-inflammatory and anticancer properties. In the last decade, large-scale randomised controlled trials of pharmacological delivery of O3F
Autor:
Henry Watson, SL Perry, Philip Quirke, Amanda D. Race, Paul M. Loadman, Giles J. Toogood, Gael Nana, Mark A. Hull, Suparna Mitra, Henry M. Wood, Caroline Young
Publikováno v:
The Journal of Nutrition
Background Oral administration of purified omega-3 (ω-3) PUFAs is associated with changes to the fecal microbiome. However, it is not known whether this effect is associated with increased PUFA concentrations in the gut. Objectives We investigated t
Autor:
Caitlin R. Long, Joanne S. Porter, Michael Bell, Mark Q. Hull, Andrew Want, Robert Ewan Harris
Publikováno v:
Biofouling. 37:433-451
A novel system was developed to deploy settlement panels to monitor biofouling growth in situ and evaluate antifouling coatings at depths representative of operational conditions of full-scale marine renewable energy devices. Biofouling loading, spec