Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Mark A F Kendall"'
Autor:
Frances E Pearson, Celia L McNeilly, Michael L Crichton, Clare A Primiero, Sally R Yukiko, Germain J P Fernando, Xianfeng Chen, Sarah C Gilbert, Adrian V S Hill, Mark A F Kendall
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67888 (2013)
The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical
Externí odkaz:
https://doaj.org/article/939bada31aad4beab2f46dab10020487
Autor:
Germain J P Fernando, Xianfeng Chen, Tarl W Prow, Michael L Crichton, Emily J Fairmaid, Michael S Roberts, Ian H Frazer, Lorena E Brown, Mark A F Kendall
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10266 (2010)
BackgroundOver 14 million people die each year from infectious diseases despite extensive vaccine use [1]. The needle and syringe--first invented in 1853--is still the primary delivery device, injecting liquid vaccine into muscle. Vaccines could be f
Externí odkaz:
https://doaj.org/article/513f0894b14147b3946ebd930b55e4f0
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13460 (2010)
BACKGROUND: Better delivery systems are needed for routinely used vaccines, to improve vaccine uptake. Many vaccines contain alum or alum based adjuvants. Here we investigate a novel dry-coated densely-packed micro-projection array skin patch (Nanopa
Externí odkaz:
https://doaj.org/article/7f32d55947544ab2a2594dfda5c74e29
Autor:
Germain J. P. Fernando, Hwee-Ing Ng, Mark A. F. Kendall, Zewen K. Tuong, Stefano C. Meliga, Ian H. Frazer, Alexandra C. I. Depelsenaire
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-12 (2019)
NPJ Vaccines
NPJ Vaccines
Chemical adjuvants are typically used to improve immune responses induced by immunisation with protein antigens. Here we demonstrate an approach to enhance immune responses that does not require chemical adjuvants. We applied microprojection arrays t
Autor:
Mark A. F. Kendall, Nicole M.D. van der Burg, Paula Kuo, Michael L. Crichton, Alexandra C. I. Depelsenaire, Simon Phipps
Publikováno v:
Journal of Controlled Release. 302:190-200
In a low inflammatory skin environment, Langerhans cells (LCs) - but not dermal dendritic cells (dDCs) - contribute to the pivotal process of tolerance induction. Thus LCs are a target for specific-tolerance therapies. LCs reside just below the strat
Autor:
Isha N. Haridass, Jonathan C. J. Wei, Jeffrey E. Grice, Michael S. Roberts, Michael L. Crichton, Mark A. F. Kendall, Heather A. E. Benson, Yousuf H. Mohammed, Washington Y. Sanchez, Stefano C. Meliga
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Microscale medical devices are being developed for targeted skin delivery of vaccines and the extraction of biomarkers, with the potential to revolutionise healthcare in both developing and developed countries. The effective clinical development of t
Autor:
Jacob W. Coffey, Nicole M. D. van der Burg, Thippayawan Rananakomol, Hwee-Ing Ng, Germain J. P. Fernando, Mark A. F. Kendall
Publikováno v:
Advanced NanoBiomed Research. 2:2100151
Publikováno v:
Microneedling in Clinical Practice ISBN: 9781315265612
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4af06f4d1ff3d31ddeae8e28e668b4
https://doi.org/10.1201/9781315265612-2
https://doi.org/10.1201/9781315265612-2
Autor:
Ian H. Frazer, Janin Chandra, Lynn Tolley, Mark E. Cooper, Shuai Cui, Rituparna Chakraborty, Mark A. F. Kendall
Publikováno v:
Experimental Dermatology. 27:71-79
The molecular links between sterile inflammation and induction of adaptive immunity have not been fully identified. Here, we examine how damage-associated molecular patterns (DAMPs), as opposed to pathogen-associated molecules (PAMPs), regulate the i
Autor:
Lisbeth Grøndahl, Paul R. Young, Kye J. Robinson, Jacob W. Coffey, Mark A. F. Kendall, Simon R. Corrie, Khai Tuck Lee, David A. Muller
Publikováno v:
Langmuir. 33:773-782
Immunoassays are ubiquitous across research and clinical laboratories, yet little attention is paid to the effect of the substrate material on the assay performance characteristics. Given the emerging interest in wearable immunoassay formats, investi