Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Mark A, Prendergast"'
Publikováno v:
Poultry Science, Vol 101, Iss 5, Pp 101790- (2022)
ABSTRACT: Ethanol is one of the most widely used and abused drugs. Following ethanol consumption, ethanol enters the bloodstream from the small intestine where it gets distributed to peripheral tissues. In the bloodstream, ethanol is cleared from the
Externí odkaz:
https://doaj.org/article/52708c1b15f04a69879b6c803ff1f5a2
Publikováno v:
Psychopharmacology. 240:295-301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63758b57d5e818ed80715f7a6dcc9567
https://doi.org/10.1007/s00213-022-06299-y
https://doi.org/10.1007/s00213-022-06299-y
Publikováno v:
PsychopharmacologyReferences.
Alcohol use disorder (AUD) has been shown to be associated with a dysregulated stress system. Reducing the stress hormone corticosterone (CORT), that binds to glucocorticoid receptors, may attenuate the rewarding properties of drugs of abuse. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12d5ab09c4b472759d983329c0730ade
https://pubmed.ncbi.nlm.nih.gov/36607385
https://pubmed.ncbi.nlm.nih.gov/36607385
Autor:
Tracy L. Nolen, Emily D. Denehy, Lindsey R. Hammerslag, Benjamin Carper, Michael T. Bardo, Mark A. Prendergast
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Opioid use disorder (OUD) is highly comorbid with stress-related disorders, and stress can serve as a trigger for reinstatement of drug seeking. Glucocorticoid receptor (GR) antagonists such as mifepristone (RU-486) may be effective agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1009fae15062f38fc9ec9f97f95eed0c
https://doi.org/10.1007/s00213-021-05865-0
https://doi.org/10.1007/s00213-021-05865-0
Autor:
Michael T. Bardo, Cassie M. Chandler, Emily D. Denehy, Benjamin A. Carper, Mark A. Prendergast, Tracy L. Nolen
Publikováno v:
Experimental and clinical psychopharmacology.
There is comorbidity between posttraumatic stress disorder (PTSD) and opioid use disorder (OUD), perhaps because PTSD-like stressful experiences early in life alter the hypothalamic-pituitary-adrenal stress axis to increase the risk for OUD. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1300636a37b50fa963bb684eff1067c
https://pubmed.ncbi.nlm.nih.gov/35587421
https://pubmed.ncbi.nlm.nih.gov/35587421
Autor:
Jeffrey A. Rumbaugh, Muznabanu Bachani, Wenxue Li, Tracy R. Butler, Katherine J. Smith, Mario A. Bianchet, Tongguang Wang, Mark A. Prendergast, Ned Sacktor, Avindra Nath
Publikováno v:
Neurobiology of Disease, Vol 49, Iss , Pp 169-176 (2013)
Purpose: Human immunodeficiency virus-1 (HIV)-associated neurocognitive disorder (HAND) is a neurodegenerative disease for which there is no available neuroprotective therapy. Viral proteins, such as Tat, have been implicated as agents of neurotoxici
Externí odkaz:
https://doaj.org/article/a490248892804d1ea9209d44855c0247
Autor:
Michael T. Bardo, Peter A. Crooks, Kimberly Nixon, Linda P. Dwoskin, Richard L. Bell, Sarah E. Maggio, Guangrong Zheng, Meredith A. Saunders, Mark A. Prendergast
Publikováno v:
Drug and Alcohol Dependence. 193:154-161
Background Although pharmacotherapies are available for alcohol (EtOH) or tobacco use disorders individually, it may be possible to develop a single pharmacotherapy to treat heavy drinking tobacco smokers by capitalizing on the commonalities in their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636dcc72d924d3927b56c9fb0e3c6cf8
https://doi.org/10.1016/j.drugalcdep.2018.09.008
https://doi.org/10.1016/j.drugalcdep.2018.09.008
Publikováno v:
Behavioural Brain Research. 338:143-152
Until recently, there were few rodent models available to study the interaction of post-traumatic stress disorder (PTSD) and drug taking. Like PTSD, single prolonged stress (SPS) produces hypothalamic-pituitary-adrenal (HPA) axis dysfunction and alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9703414c872a768df8108158732b1dfe
https://doi.org/10.1016/j.bbr.2017.10.023
https://doi.org/10.1016/j.bbr.2017.10.023
Autor:
Manjula Sunkara, Jon S. Thorson, Yinan Zhang, Samantha A. Scott, Sherif I. Elshahawi, Ryan R. Hughes, Larissa V. Ponomareva, Jianjun Zhang, Khaled A. Shaaban, Andrew J. Morris, Meredith A. Saunders, Mark A. Prendergast, Sydney R. Winchester
Publikováno v:
Journal of Natural Products. 80:12-18
The assessment of glycosyl-scanning to expand the molecular and functional diversity of metabolites from the underground coal mine fire-associated Streptomyces sp. RM-14-6 is reported. Using the engineered glycosyltransferase OleD Loki and a 2-chloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67a833f2ecdddb80e6e00f56ccccdba
https://doi.org/10.1021/acs.jnatprod.6b00949
https://doi.org/10.1021/acs.jnatprod.6b00949