Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mark A, Muesing"'
Autor:
Benjamin Trinité, Chi N Chan, Caroline S Lee, Saurabh Mahajan, Yang Luo, Mark A Muesing, Joy M Folkvord, Michael Pham, Elizabeth Connick, David N Levy
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110719 (2014)
HIV-1 hijacks and disrupts many processes in the cells it infects in order to suppress antiviral immunity and to facilitate its replication. Resting CD4 T cells are important early targets of HIV-1 infection in which HIV-1 must overcome intrinsic bar
Externí odkaz:
https://doaj.org/article/512728fc6e724f9e8b132fac1e8e0316
Autor:
David Sargeant, Sandeep Deverasetty, Yang Luo, Angel Villahoz Baleta, Stephanie Zobrist, Viraj Rathnayake, Jacqueline C Russo, Jay Vyas, Mark A Muesing, Martin R Schiller
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20122 (2011)
Many bioinformatic databases and applications focus on a limited domain of knowledge federating links to information in other databases. This segregated data structure likely limits our ability to investigate and understand complex biological systems
Externí odkaz:
https://doaj.org/article/d0995748f76b414f9cce7fed833898f4
Autor:
Aliza G Lloyd, Satoshi Tateishi, Paul D Bieniasz, Mark A Muesing, Masaru Yamaizumi, Lubbertus C F Mulder
Publikováno v:
PLoS Pathogens, Vol 2, Iss 5, p e40 (2006)
Host factors belonging to the DNA repair machineries are assumed to aid retroviruses in the obligatory step of integration. Here we describe the effect of DNA repair molecule Rad18, a component of the post-replication repair pathway, on viral infecti
Externí odkaz:
https://doaj.org/article/5dcfe56be2894fb7878bd35cd7eee011
Publikováno v:
Future Virology. 12:5-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9da6ee6c7705560132c042f7f94a0b4
https://doi.org/10.2217/fvl-2016-0115
https://doi.org/10.2217/fvl-2016-0115
Autor:
Erica Y. Jacobs, James M. Binley, Ileana M. Cristea, Sarah Keegan, Todd M. Greco, Kevin D. Mohammed, Yang Luo, Tommy Tong, Brian T. Chait, David Fenyö, Michael P. Rout, Mark A. Muesing
Publikováno v:
Nature Microbiology. 1
Although genetically compact, HIV-1 commandeers vast arrays of cellular machinery to sustain and protect it during cycles of viral outgrowth. Transposon-mediated saturation linker scanning mutagenesis was used to isolate fully replication-competent v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec4d0e26154f8af7011d12eee8bcfbf
https://doi.org/10.1038/nmicrobiol.2016.68
https://doi.org/10.1038/nmicrobiol.2016.68
Publikováno v:
Virology. 364(1):227-236
HIV-1 integrase (IN) catalyzes biochemical reactions required for viral cDNA insertion into host cell chromosomal DNA, an essential step in the HIV-1 replication cycle. In one of these reactions, the two ends of the linear viral cDNA are believed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd245ca269424d03af89a0cfb8e47ac
Autor:
Simone Cowan, Theodora Hatziioannou, Mark A. Muesing, Heinrich G. Göttlinger, Tshaka Cunningham, Paul D. Bieniasz
Publikováno v:
Proceedings of the National Academy of Sciences. 99:11914-11919
Many nonhuman primate cells are unable to support the replication of HIV-1, whereas others are nonpermissive for infection by simian immunodeficiency virus from macaques (SIVmac). Here, we show that restricted HIV-1 and SIVmac infection of primate ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f316fa06814503f904ab3984a9f3eb
https://doi.org/10.1073/pnas.162299499
https://doi.org/10.1073/pnas.162299499
Publikováno v:
Journal of Biological Chemistry. 277:27489-27493
We have previously shown that human immunodeficiency virus-1 (HIV-1) integrase is an unstable protein and a substrate for the N-end rule degradation pathway. This degradation pathway shares its ubiquitin-conjugating enzyme, Rad6, with the post-replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a0b592c12487eeff76394d28be5fc2
https://doi.org/10.1074/jbc.m203061200
https://doi.org/10.1074/jbc.m203061200
Autor:
Mark A. Muesing, Yang Luo
Publikováno v:
Future virology. 9(11)
ABSTRACT A molecular understanding of viral infection requires a multi-disciplinary approach. Mass spectrometry has emerged as an indispensable tool to investigate the complex and dynamic interactions between HIV-1 and its host. It has been employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c1eb73779ea0b7b4cc99a205a2bf91
https://pubmed.ncbi.nlm.nih.gov/25544858
https://pubmed.ncbi.nlm.nih.gov/25544858
Autor:
Christine A. Power, Alexandra Trkola, John P. Moore, Mark A. Muesing, Amanda E. I. Proudfoot, Cynthia J. Gordon
Publikováno v:
Europe PubMed Central
We have studied the effects of CC-chemokines on human immunodeficiency virus type 1 (HIV-1) infection, focusing on the infectivity enhancement caused by RANTES. High RANTES concentrations increase the infectivity of HIV-1 isolates that use CXC-chemok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337fa582024f6d70fa36acaec316bfb8
https://doi.org/10.1128/jvi.73.1.684-694.1999
https://doi.org/10.1128/jvi.73.1.684-694.1999