Zobrazeno 1 - 10
of 1 793
pro vyhledávání: '"Mark A, Lewis"'
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Autor:
Matthew Gagne, Barbara J. Flynn, Christopher Cole Honeycutt, Dillon R. Flebbe, Shayne F. Andrew, Samantha J. Provost, Lauren McCormick, Alex Van Ry, Elizabeth McCarthy, John-Paul M. Todd, Saran Bao, I-Ting Teng, Shir Marciano, Yinon Rudich, Chunlin Li, Shilpi Jain, Bushra Wali, Laurent Pessaint, Alan Dodson, Anthony Cook, Mark G. Lewis, Hanne Andersen, Jiří Zahradník, Mehul S. Suthar, Martha C. Nason, Kathryn E. Foulds, Peter D. Kwong, Mario Roederer, Gideon Schreiber, Robert A. Seder, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract SARS-CoV-2 has the capacity to evolve mutations that escape vaccine- and infection-acquired immunity and antiviral drugs. A variant-agnostic therapeutic agent that protects against severe disease without putting selective pressure on the vir
Externí odkaz:
https://doaj.org/article/398a2dfd9ac6483f881f1a81f6f17840
Autor:
María Fernández‐Rhodes, Emma Buchan, Stephanie D. Gagnon, Jiani Qian, Lee Gethings, Rebecca Lees, Ben Peacock, Andrew J. Capel, Neil R. W. Martin, Pola Goldberg Oppenheimer, Mark P. Lewis, Owen G. Davies
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 8, Pp n/a-n/a (2024)
Abstract Skeletal muscle (SM) acts as a secretory organ, capable of releasing myokines and extracellular vesicles (SM‐EVs) that impact myogenesis and homeostasis. While age‐related changes have been previously reported in murine SM‐EVs, no stud
Externí odkaz:
https://doaj.org/article/25f03d8b84794b319851e03ae9786910
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionSuccessful vaccine promotion communication strategies require knowing how eligible recipients will respond to the opportunity to get vaccinated. Two main classes of recipients are myopic rationalists, those who receive a dose of vaccine o
Externí odkaz:
https://doaj.org/article/6a104ad50aef4253b29d7b35f6c17862
Autor:
Bradley J. Wilkes, Derek B. Archer, Anna L. Farmer, Carly Bass, Hannah Korah, David E. Vaillancourt, Mark H. Lewis
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Restricted repetitive behavior (RRB) is one of two behavioral domains required for the diagnosis of autism spectrum disorder (ASD). Neuroimaging is widely used to study brain alterations associated with ASD and the domain of socia
Externí odkaz:
https://doaj.org/article/ac5c0a1944614263acc36b28b25a0e7d
Autor:
Peter R. Thompson, Peter D. Harrington, Conor D. Mallory, Subhash R. Lele, Erin M. Bayne, Andrew E. Derocher, Mark A. Edwards, Mitch Campbell, Mark A. Lewis
Publikováno v:
Movement Ecology, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Background Animals of many different species, trophic levels, and life history strategies migrate, and the improvement of animal tracking technology allows ecologists to collect increasing amounts of detailed data on these movements. Underst
Externí odkaz:
https://doaj.org/article/abe92e9399d44ad9b6e9662484080752
Autor:
Bhawna Sharma, Elena Bekerman, Hoa Truong, Johnny Lee, Maria Gamez-Guerrero, Archana Boopathy, Rohit Mital, Katell Bidet Huang, Sarah Ahmadi-Erber, Raphaela Wimmer, Sophie Schulha, Henning Lauterbach, Klaus Orlinger, Silpa Suthram, Mark G. Lewis, Wade Blair, Tariro Makadzange, Romas Geleziunas, Jeffrey P. Murry, Sarah Schmidt
Publikováno v:
Vaccines, Vol 12, Iss 7, p 735 (2024)
Arenavirus-based vectors are being investigated as therapeutic vaccine candidates with the potential to elicit robust CD8 T-cell responses. We compared the immunogenicity of replicating (artPICV and artLCMV) and non-replicating (rPICV and rLCMV) aren
Externí odkaz:
https://doaj.org/article/12cd484f588c476caa2e1468f51b5006
Autor:
Mark David Lewis, Stephanie Cayula, Richard W. Gould, William David Miller, Igor Shulman, Geoffrey B. Smith, Travis A. Smith, David Wang, Hemantha Wijesekera
Publikováno v:
Remote Sensing, Vol 16, Iss 11, p 1965 (2024)
Bio-optical and physical measurements were collected in the Mississippi Sound (Northern Gulf of Mexico) during the spring of 2018 as part of the Integrated Coastal Bio-Optical Dynamics project. The goal was to examine the impact of atmospheric and ti
Externí odkaz:
https://doaj.org/article/cf699647ca5340db9e1222196d975373
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307290 (2024)
Restricted, repetitive behaviors are common symptoms in neurodevelopmental disorders including autism spectrum disorder. Despite being associated with poor developmental outcomes, repetitive behaviors remain poorly understood and have limited treatme
Externí odkaz:
https://doaj.org/article/57fb720c9c934a838831442881280495
Autor:
Felix Wussow, Mindy Kha, Taehyun Kim, Minh Ly, Marcal Yll-Pico, Swagata Kar, Mark G. Lewis, Flavia Chiuppesi, Don J. Diamond
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Emerging SARS-CoV-2 Omicron subvariants continue to disrupt COVID-19 vaccine efficacy through multiple immune mechanisms including neutralizing antibody evasion. We developed COH04S1, a synthetic modified vaccinia Ankara vector that co-expre
Externí odkaz:
https://doaj.org/article/35041c384f06436e9a5694235594dce6
Autor:
Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J. Martinot, Tochi Anioke, Olivia C. Powers, Kevin Hall, David Hope, Jessica Miller, Nichole P. Hachmann, Benjamin Chung, Sarah Gardner, Daniel Sellers, Julia Barrett, Mark G. Lewis, Hanne Andersen, Harry Kleanthous, Ki-Woen Seo, Su Jeen Lee, Yong Wook Park, Hun Kim, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Despite the availability of several effective SARS-CoV-2 vaccines, additional vaccines will be required for optimal global vaccination. In this study, we investigate the immunogenicity and protective efficacy of the GBP510 protein subunit va
Externí odkaz:
https://doaj.org/article/2859911f0f034613a627935fa3b765b4